stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

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What functions are associated with stearic acid?


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What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

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What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Fodorová M et al. Structural features of lipid A of Rickettsia typhi. 2011 Acta Virol. pmid:21434703
Kerti A et al. Content of retinol and retinyl esters in blood plasma, liver, kidney and reproductive organs of Japanese quails. 2002 Acta Vet. Hung. pmid:12498148
Stanisz B The influence of pharmaceutical excipients on quinapril hydrochloride stability. 2005 May-Jun Acta Pol Pharm pmid:16193811
Muzíková J and Sináglová P Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses. 2013 Jan-Feb Acta Pol Pharm pmid:23610968
Hussain T et al. Effect of two hydrophobic polymers on the release of gliclazide from their matrix tablets. 2013 Jul-Aug Acta Pol Pharm pmid:23923399
Stanisz B et al. Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. 2010 Jan-Feb Acta Pol Pharm pmid:20210086
Muzíková J et al. A study of micronized poloxamers as lubricants in direct compression of tablets. 2013 Nov-Dec Acta Pol Pharm pmid:24383332
Nath B et al. Preparation and in vitro dissolution profile of zidovudine loaded microspheres made of Eudragit RS 100, RL 100 and their combinations. 2011 May-Jun Acta Pol Pharm pmid:21648196
BozdaÄŸ-Pehlivan S et al. Evaluation of drug-excipient interaction in the formulation of celecoxib tablets. 2011 May-Jun Acta Pol Pharm pmid:21648198
GOERANSSON G THE METABOLISM OF FATTY ACIDS IN THE RAT. IV. STEARIC ACID. 1965 Acta Physiol. Scand. pmid:14321752