stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

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What functions are associated with stearic acid?


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What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

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What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Wang N et al. The mechanism of hydrogen sulfide adsorption on fine rubber particle media (FRPM). 2013 J. Hazard. Mater. pmid:23876257
Mohamed IO Lipase-catalyzed acidolysis of palm mid fraction oil with palmitic and stearic Fatty Acid mixture for production of cocoa butter equivalent. 2013 Appl. Biochem. Biotechnol. pmid:23877586
Vitturi DA et al. Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. 2013 J. Biol. Chem. pmid:23878198
Saeedi Vahdat A et al. Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets. 2013 Int J Pharm pmid:23820132
Li L et al. Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. 2013 Int J Pharm pmid:23624081
Negi JS et al. Development of solid lipid nanoparticles (SLNs) of lopinavir using hot self nano-emulsification (SNE) technique. 2013 Eur J Pharm Sci pmid:23153618
Nakagawa H et al. Real-time monitoring of lubrication properties of magnesium stearate using NIR spectrometer and thermal effusivity sensor. 2013 Int J Pharm pmid:23174413
Otsuka Y et al. Effects of polymorphic transformation on pharmaceutical properties of direct compressed tablets containing theophylline anhydrate bulk powder under high humidity. 2013 Colloids Surf B Biointerfaces pmid:23178204
Azordegan N et al. Carcinogenesis alters fatty acid profile in breast tissue. 2013 Mol. Cell. Biochem. pmid:23180247
Schrank S et al. Microstructure of calcium stearate matrix pellets: a function of the drying process. 2013 J Pharm Sci pmid:23983150
Yang C et al. Production of aviation fuel via catalytic hydrothermal decarboxylation of fatty acids in microalgae oil. 2013 Bioresour. Technol. pmid:23973977
Barber E et al. Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24012207
Cunha TA et al. Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. 2013 AAPS PharmSciTech pmid:23897034
Høstmark AT et al. Increased serum triglycerides and reduced HDL cholesterol in male rats after intake of ammonium chloride for 3 weeks. 2013 Lipids Health Dis pmid:23800210
Saroja C and Lakshmi PK Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. 2013 Acta Pharm pmid:23482314
Pethrick RA and Song M Dielectric studies of amylose, amylopectin and amylose-stearic acid complexes. 2013 Carbohydr Polym pmid:23399185
Kwan HY et al. The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells. 2013 J. Gastroenterol. pmid:22722903
Subbaramaiah K et al. Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice. 2013 Cancer Prev Res (Phila) pmid:23880231
Tammaro A et al. Magnesium stearate: an underestimated allergen. 2012 Oct-Dec J. Biol. Regul. Homeost. Agents pmid:23241129
Hentzschel CM et al. Comparison of traditional and novel tableting excipients: physical and compaction properties. 2012 Nov-Dec Pharm Dev Technol pmid:21740091
Khan FN and Dehghan MH Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. 2012 Jan-Mar Sci Pharm pmid:22396916
Pujeri SS et al. Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. 2012 Jan-Mar Sci Pharm pmid:22396908
Samanta AK et al. Cone milling of compacted flakes: process parameter selection by adopting the minimal fines approach. 2012 Int J Pharm pmid:22001841
Tay T et al. Dissolution of a poorly water-soluble drug dry coated with magnesium and sodium stearate. 2012 Eur J Pharm Biopharm pmid:22036990
Abe H and Otsuka M Effects of lubricant-mixing time on prolongation of dissolution time and its prediction by measuring near infrared spectra from tablets. 2012 Drug Dev Ind Pharm pmid:21954869
Zanon NC et al. Immbolization of uricase enzyme in Langmuir and Langmuir-Blodgett films of fatty acids: possible use as a uric acid sensor. 2012 J Colloid Interface Sci pmid:21875709
Sabir A et al. The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.). 2012 J. Sci. Food Agric. pmid:22271548
Arya A et al. Chloroform Fraction of Centratherum anthelminticum (L.) Seed Inhibits Tumor Necrosis Factor Alpha and Exhibits Pleotropic Bioactivities: Inhibitory Role in Human Tumor Cells. 2012 Evid Based Complement Alternat Med pmid:22474512
Vega Mercado F et al. Modulation of the domain topography of biphasic monolayers of stearic acid and dimyristoyl phosphatidylcholine. 2012 Chem. Phys. Lipids pmid:22274694
Milicic A et al. Small cationic DDA:TDB liposomes as protein vaccine adjuvants obviate the need for TLR agonists in inducing cellular and humoral responses. 2012 PLoS ONE pmid:22470545
Mason P et al. SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids. 2012 PLoS ONE pmid:22457791
Morales A et al. Quantitative analysis of hydroperoxy-, keto- and hydroxy-dienes in refined vegetable oils. 2012 J Chromatogr A pmid:22321954
Olivieri C et al. Phylogenetic position of a copper age sheep (Ovis aries) mitochondrial DNA. 2012 PLoS ONE pmid:22457789
Nussbaum M and Paz Y Ultra-thin SiO2 layers on TiO2: improved photocatalysis by enhancing products' desorption. 2012 Phys Chem Chem Phys pmid:22298253
Ahn BJ et al. Solvent-free acid-catalyzed ring-opening of epoxidized oleochemicals using stearates/stearic acid, and its applications. 2012 J. Agric. Food Chem. pmid:22304525
Liu X et al. Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. 2012 PLoS Pathog. pmid:22412372
Lee AL and Kim CB The effect of erythromycin on gastrointestinal motility in subtotal gastrectomized patients. 2012 J Korean Surg Soc pmid:22403748
Visioli F et al. Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response. 2012 Front Physiol pmid:22393325
Sampey BP et al. Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. 2012 PLoS ONE pmid:22701716
Stryjecki C et al. Enzymatic activity and genetic variation in SCD1 modulate the relationship between fatty acids and inflammation. 2012 Mol. Genet. Metab. pmid:22209225
Casiraghi A et al. The influence of the polar head and the hydrophobic chain on the skin penetration enhancement effect of poly(ethylene glycol) derivatives. 2012 AAPS PharmSciTech pmid:22232021
Wei CC and Ge ZQ Influence of electrolyte and poloxamer 188 on the aggregation kinetics of solid lipid nanoparticles (SLNs). 2012 Drug Dev Ind Pharm pmid:22181005
Singh AV and Nath LK Evaluation of acetylated moth bean starch as a carrier for controlled drug delivery. 2012 Int. J. Biol. Macromol. pmid:22210486
Basseri S and Austin RC Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. 2012 Biochem Res Int pmid:22195283
Seeliger JC et al. Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. 2012 J. Biol. Chem. pmid:22194604
Hao J et al. Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. 2012 Eur J Pharm Sci pmid:22820033
Severino P et al. Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. 2012 J Drug Deliv pmid:22175030
Han K et al. Novel gene transfer vectors based on artificial recombinant multi-functional oligopeptides. 2012 Int J Pharm pmid:22796172
Kottala N et al. Influence of compaction properties and interfacial topography on the performance of bilayer tablets. 2012 Int J Pharm pmid:22728259
Chansela P et al. Composition and localization of lipids in Penaeus merguiensis ovaries during the ovarian maturation cycle as revealed by imaging mass spectrometry. 2012 PLoS ONE pmid:22432001
Xie YT et al. Brain-targeting study of stearic acid-grafted chitosan micelle drug-delivery system. 2012 Int J Nanomedicine pmid:22802685
El Semary NA The antimicrobial profile of extracts of a Phormidium-like cyanobacterium changes with phosphate levels. 2012 World J. Microbiol. Biotechnol. pmid:22806854
Reddy KR et al. Rationale, challenges, and participants in a Phase II trial of a botanical product for chronic hepatitis C. 2012 Clin Trials pmid:22058086
Ruiz M et al. A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. 2012 PLoS ONE pmid:23056435
Kakisaka K et al. Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21995961
Galvao TF et al. High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects. 2012 Cardiovasc. Res. pmid:21960686
Choi du H et al. A new experimental design method to optimize formulations focusing on a lubricant for hydrophilic matrix tablets. 2012 Drug Dev Ind Pharm pmid:22348254
Kim DH et al. Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function. 2012 Colloids Surf B Biointerfaces pmid:22361356
Honkanen AM et al. Characterization of the disappearance and formation of biohydrogenation intermediates during incubations of linoleic acid with rumen fluid in vitro. 2012 J. Dairy Sci. pmid:22365221
Kushner J Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume. 2012 Int J Pharm pmid:22405966
Matsui H et al. Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes. 2012 PLoS ONE pmid:22413010
Zhang ZH et al. Solid lipid nanoparticles modified with stearic acid-octaarginine for oral administration of insulin. 2012 Int J Nanomedicine pmid:22848162
Trupp M et al. Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. 2012 PLoS ONE pmid:22808006
Liu J et al. Stearoyl-acyl carrier protein desaturase gene from the oleaginous microalga Chlorella zofingiensis: cloning, characterization and transcriptional analysis. 2012 Planta pmid:22855030
Carol D et al. Synergistic effect of calcium stearate and photo treatment on the rate of biodegradation of low density polyethylene spent saline vials. 2012 Indian J. Exp. Biol. pmid:22822530
Zeng XJ et al. [Chemical constituents of Berchemia lineate]. 2012 Zhong Yao Cai pmid:22822666
Serra Bonvehi J and Orantes Bermejo FJ Detection of adulterated commercial Spanish beeswax. 2012 Food Chem pmid:26434344
Lou CW et al. PLA/ β-TCP complex tubes: the mechanical properties and applications of artificial bone. 2012 J Biomater Sci Polym Ed pmid:21968651
Varshosaz J et al. Optimization of self-assembling properties of fatty acids grafted to methoxy poly(ethylene glycol) as nanocarriers for etoposide. 2012 Acta Pharm pmid:22472447
Kurotani K et al. High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. 2012 Nutr Res pmid:23084639
Lee SH et al. End point determination of blending process for trimebutine tablets using principle component analysis (PCA) and partial least squares (PLS) regression. 2012 Arch. Pharm. Res. pmid:23054717
Osmond G et al. Metal stearate distributions in modern artists' oil paints: surface and cross-sectional investigation of reference paint films using conventional and synchrotron infrared microspectroscopy. 2012 Appl Spectrosc pmid:23031696
McNamee CE et al. Effect of the degree of dissociation of molecules in a monolayer at an air/water interface on the force between the monolayer and a like-charged particle in the subphase. 2012 J Phys Chem B pmid:23092192
Chu BB et al. [XANES study of lead speciation in duckweed]. 2012 Guang Pu Xue Yu Guang Pu Fen Xi pmid:23016367
Sharma P et al. Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies. 2012 J Biomed Nanotechnol pmid:23030001
Pijls BG et al. Differences in long-term fixation between mobile-bearing and fixed-bearing knee prostheses at ten to 12 years' follow-up: a single-blinded randomised controlled radiostereometric trial. 2012 J Bone Joint Surg Br pmid:23015562
Guzzi R et al. Dynamics and binding affinity of spin-labeled stearic acids in β-lactoglobulin: evidences from EPR spectroscopy and molecular dynamics simulation. 2012 J Phys Chem B pmid:22950964
Charpentier PA et al. Nano-TiO2/polyurethane composites for antibacterial and self-cleaning coatings. 2012 Nanotechnology pmid:23037881
Akinsete JA et al. Consumption of high ω-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice. 2012 Carcinogenesis pmid:22045025
Baldwin AC et al. A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22436701
Weiss VM et al. Poly(glycerol adipate)-fatty acid esters as versatile nanocarriers: From nanocubes over ellipsoids to nanospheres. 2012 J Control Release pmid:21971295
Tuli RA et al. Polycaprolactone microspheres as carriers for dry powder inhalers: effect of surface coating on aerosolization of salbutamol sulfate. 2012 J Pharm Sci pmid:21956254
Shuhendler AJ et al. Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry. 2012 J Control Release pmid:21939700
Wang X et al. Volatile components of ethanolic extract from broccolini leaves. 2012 Nat. Prod. Res. pmid:21859369
Suo T et al. Fixed-point and stratified analysis of the fine structure and composition of five gallstones with Fourier transform infrared (FT-IR) specular reflection spectroscopy. 2012 Microsc. Res. Tech. pmid:21809418
Mai K et al. Rosiglitazone increases fatty acid Δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo. 2012 Metab. Clin. Exp. pmid:21741058
Tokudome Y and Otsuka M Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. 2012 Biol. Pharm. Bull. pmid:22975500
Gören AC et al. Fatty acid composition and chemotaxonomic evaluation of species of Stachys. 2012 Nat. Prod. Res. pmid:21859257
Lu J et al. A molecular mechanism for modulating plasma Zn speciation by fatty acids. 2012 J. Am. Chem. Soc. pmid:22239162
Smathers RL et al. Characterization of 4-HNE modified L-FABP reveals alterations in structural and functional dynamics. 2012 PLoS ONE pmid:22701647
Foster SP and Anderson KG Synthetic rates of key stored fatty acids in the biosynthesis of sex pheromone in the moth Heliothis virescens. 2012 Insect Biochem. Mol. Biol. pmid:22982110
Nesarikar VV et al. Instrumented roll technology for the design space development of roller compaction process. 2012 Int J Pharm pmid:22286023
Toubiana D et al. Metabolic profiling of a mapping population exposes new insights in the regulation of seed metabolism and seed, fruit, and plant relations. 2012 PLoS Genet. pmid:22479206
Eili M et al. Degradability enhancement of poly(lactic acid) by stearate-Zn(3)Al LDH nanolayers. 2012 Int J Mol Sci pmid:22942682
Hayashi Y et al. Latent structure analysis of the process variables and pharmaceutical responses of an orally disintegrating tablet. 2012 Chem. Pharm. Bull. pmid:22878814
Xie J et al. Composition of fatty oils from semen ziziphi spinosae and its cardiotonic effect on isolated toad hearts. 2012 Nat. Prod. Res. pmid:21707231
Tamokou Jde D et al. Antioxidant and antimicrobial activities of ethyl acetate extract, fractions and compounds from stem bark of Albizia adianthifolia (Mimosoideae). 2012 BMC Complement Altern Med pmid:22809287
Wang L et al. Effect of rare Earth ions on the properties of composites composed of ethylene vinyl acetate copolymer and layered double hydroxides. 2012 PLoS ONE pmid:22693627
Wong RH et al. Chronic effects of a wild green oat extract supplementation on cognitive performance in older adults: a randomised, double-blind, placebo-controlled, crossover trial. 2012 Nutrients pmid:22690320
Bederman I et al. Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:22679004