stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

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What functions are associated with stearic acid?


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What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

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What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
FOTI L et al. [In vitro liver biosynthesis of cholesterol from acetate, stearate and linoleate 1-C-14]. 1961 Boll. Soc. Ital. Biol. Sper. pmid:13958917
DAVIDOFF F and KORN ED Synthesis of unsaturated fatty acids in the cellular slime mold. 1962 Biochem. Biophys. Res. Commun. pmid:14025332
DEYKIN D and GOODMAN DS The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes. 1962 J. Biol. Chem. pmid:14027461
TROUT DL and ESTES EH Factors affecting liver uptake of serum free stearic acid-1-C14. 1962 Am. J. Physiol. pmid:13994303
WALLEN LL et al. The microbiological production of 10-hydroxystearic acid from oleic acid. 1962 Arch. Biochem. Biophys. pmid:13998583
CREASEY WA Observations on the activation of stearic acid by rat-liver preparations. 1962 Biochim. Biophys. Acta pmid:14023748
JAMES AT [Studies on the biosynthesis of 18 carbon mono-and tri-unsaturated fatty acids by gas phase chromatography]. 1962 Bull. Soc. Chim. Biol. pmid:13957228
FOSSA T [Inhibition of hepatic glucose-6-phosphatase by fatty acids and zinc ions]. 1962 Boll. Soc. Ital. Biol. Sper. pmid:13958874
BARGONI N and SISINI A [Inhibition and reactivation of the hydrolases of digestion]. 1962 Boll. Soc. Ital. Biol. Sper. pmid:13966663
NIELSEN K and SCHMIDT H [Should the standard treatment of gonorrhea be changed? Effects of the treatment of gonorrhea in 1960 in ambulant and hospitalized patients]. 1962 Manedsskr Prakt Laegegern pmid:13938514
GUTIERREZ J et al. Lipid metabolism of rumen ciliates and bacteria. I. Uptake of fatty acids by Isotricha prostoma and Entodinium simplex. 1962 Appl Microbiol pmid:13951437
KUNUGI K STUDIES ON THE SYNTHESES OF SUCROSE FATTY ACID ESTERS. IV. VELOCITY OF ALCOHOLYSIS REACTION. 1963 Chem. Pharm. Bull. pmid:14075263
PANDE SV et al. MICRODETERMINATION OF LIPIDS AND SERUM TOTAL FATTY ACIDS. 1963 Anal. Biochem. pmid:14077635
BURNS TW et al. EFFECT OF INSULIN ON PLASMA FREE FATTY ACIDS OF NORMAL SUBJECTS. 1963 J. Lab. Clin. Med. pmid:14080865
CHAKRAVORTI KP and SADHU DP STUDIES ON CHEMICAL COMPOSITION OF PROTEIN AND FAT IN THE OVIDUCT OF THE PIGEON, COLUMBA LIVIA GMELIN. 1963 Ann Biochem Exp Med pmid:14082710
WELD JT et al. Production of octadecenoic acid in plasma by Staphylococcus aureus. 1963 Proc. Soc. Exp. Biol. Med. pmid:13999824
ROSENBERG MD Cell guidance by alterations in monomolecular films. 1963 Science pmid:13974905
KUNUGI K Studies on the syntheses of sucrose fatty acid esters. II. Separation of the alcoholyses products by liquid column chromatography and determination of the contents of sucrose monostearate. 1963 Chem. Pharm. Bull. pmid:13927387
KUNUGI K Studies on the syntheses of sucrose fatty acid esters. III. Re-esterification of sucrose monostearate. 1963 Chem. Pharm. Bull. pmid:13927388
COSCIA G et al. [ASPECTS OF THE FECAL AND URINARY ELIMINATION OF LEAD IN 2 CASES OF POISONING WITH STEARATE OF LEAD]. 1963 Folia Med (Napoli) pmid:14159390