| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prostatic Diseases | D011469 | 4 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Obesity, Abdominal | D056128 | 3 associated lipids |
| Rosacea | D012393 | 13 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Gonorrhea | D006069 | 7 associated lipids |
| Calculi | D002137 | 3 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| de Sousa FF et al. | Low-temperature phase transformation studies in the stearic acid: C form. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25909902 |
| Patil H et al. | Formulation and development of pH-independent/dependent sustained release matrix tablets of ondansetron HCl by a continuous twin-screw melt granulation process. | 2015 | Int J Pharm | pmid:25863118 |
| Bera H et al. | Alginate gel-coated oil-entrapped alginate-tamarind gum-magnesium stearate buoyant beads of risperidone. | 2015 | Int. J. Biol. Macromol. | pmid:25861741 |
| Badal Tejedor M et al. | Tablet mechanics depend on nano and micro scale adhesion, lubrication and structure. | 2015 | Int J Pharm | pmid:25841569 |
| Thakral NK et al. | Compression-induced crystallization of amorphous indomethacin in tablets: characterization of spatial heterogeneity by two-dimensional X-ray diffractometry. | 2015 | Mol. Pharm. | pmid:25438193 |
| Liu Z et al. | Process optimization and kinetic evaluation for biosynthesis of D-isoascorbyl stearate. | 2015 | Bioprocess Biosyst Eng | pmid:25407728 |
| Askari M et al. | Tissue fatty acid composition and secretory phospholipase-A2 activity in oral squamous cell carcinoma. | 2015 | Clin Transl Oncol | pmid:25351172 |
| Mohanty B et al. | Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery. | 2015 | Pharm Dev Technol | pmid:24490828 |
| Guadalupe Sánchez-González E et al. | The influence of polymorphism on the manufacturability and in vitro dissolution of sulindac-containing hard gelatin capsules. | 2015 | Pharm Dev Technol | pmid:24417644 |
| Van Hoeck V et al. | Interaction between differential gene expression profile and phenotype in bovine blastocysts originating from oocytes exposed to elevated non-esterified fatty acid concentrations. | 2015 | Reprod. Fertil. Dev. | pmid:24360349 |
| Liu Z et al. | A novel stearic acid-modified hirudin peptidomimetic with improved pharmacokinetic properties and anticoagulant activity. | 2015 | Sci Rep | pmid:26400022 |
| Miao H et al. | Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1α pathway in chondrocytes. | 2015 | Sci Rep | pmid:26271607 |
| Soliman HM et al. | Utilization of Stearic acid Extracted from Olive Pomace for Production of Triazoles, Thiadiazoles and Thiadiazines Derivatives of Potential Biological Activities. | 2015 | J Oleo Sci | pmid:26250422 |
| Sasakura D et al. | Application of the quantitative detection of a change in concentration of magnesium stearate in a feeder tube of tableting manufacture by real-time near-infrared spectroscopy. | 2015 | Pharmazie | pmid:26601418 |
| Kumar Gaur P et al. | Nanovesicles of nitrendipine with lipid complex for transdermal delivery: pharmacokinetic and pharmacodynamic studies. | 2016 | Artif Cells Nanomed Biotechnol | pmid:26375758 |
| Li X et al. | Preparation of co-spray dried cushioning agent containing stearic acid for protecting pellet coatings when compressed. | 2016 | Drug Dev Ind Pharm | pmid:26289006 |
| Uğurlu T and Halaçoğlu MD | Effects of hexagonal boron nitride on dry compression mixture of Avicel DG and Starch 1500. | 2016 | Pharm Dev Technol | pmid:25716058 |
| Jójárt I et al. | Study of the compressibility of chewing gum and its applicability as an oral drug delivery system. | 2016 | Pharm Dev Technol | pmid:25673279 |
| Patadia R et al. | Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets. | 2016 | Pharm Dev Technol | pmid:25566928 |
| Yan G et al. | Preparation and evaluation of liver-targeting micelles loaded with oxaliplatin. | 2016 | Artif Cells Nanomed Biotechnol | pmid:25287740 |
| Pradhan M et al. | Influence of selected variables on fabrication of Triamcinolone acetonide loaded solid lipid nanoparticles for topical treatment of dermal disorders. | 2016 | Artif Cells Nanomed Biotechnol | pmid:25229831 |
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| Yin L et al. | Benzyl butyl phthalate promotes adipogenesis in 3T3-L1 preadipocytes: A High Content Cellomics and metabolomic analysis. | 2016 | Toxicol In Vitro | pmid:26820058 |
| Guan Q et al. | Docetaxel-Loaded Self-Assembly Stearic Acid-Modified Bletilla striata Polysaccharide Micelles and Their Anticancer Effect: Preparation, Characterization, Cellular Uptake and In Vitro Evaluation. | 2016 | Molecules | pmid:27918445 |
| Shur J et al. | From single excipients to dual excipient platforms in dry powder inhaler products. | 2016 | Int J Pharm | pmid:27262269 |
| Li T et al. | Defense priming by non-jasmonate producing fatty acids in maize (Zea mays). | 2016 | Plant Signal Behav | pmid:27763804 |
| Kanasaki Y et al. | Application of Quartz Crystal Microbalance as a Tool for Detergency Evaluation of Fatty Acid Contamination in Aqueous Systems. | 2016 | J Oleo Sci | pmid:27725481 |
| Souza AF et al. | Waste Soybean Oil and Corn Steep Liquor as Economic Substrates for Bioemulsifier and Biodiesel Production by Candida lipolytica UCP 0998. | 2016 | Int J Mol Sci | pmid:27669227 |
| Teh SS et al. | Incorporation of Palmitic Acid or Stearic Acid into Soybean Oils Using Enzymatic Interesterification. | 2016 | J Oleo Sci | pmid:27477075 |
| Simon C et al. | Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays. | 2016 | Toxicol In Vitro | pmid:27633901 |
| Sun Y et al. | Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study. | 2016 | J. Lipid Res. | pmid:27371261 |
| Shah RM et al. | Microwave-assisted formulation of solid lipid nanoparticles loaded with non-steroidal anti-inflammatory drugs. | 2016 | Int J Pharm | pmid:27789371 |
| Abreu P et al. | Contractile function recovery in severely injured gastrocnemius muscle of rats treated with either oleic or linoleic acid. | 2016 | Exp. Physiol. | pmid:27579497 |
| Garba L et al. | Heterologous Expression of PA8FAD9 and Functional Characterization of a Δ9-Fatty Acid Desaturase from a Cold-Tolerant Pseudomonas sp. A8. | 2016 | Mol. Biotechnol. | pmid:27629791 |
| Mazel V et al. | Reevaluation of the diametral compression test for tablets using the flattened disc geometry. | 2016 | Int J Pharm | pmid:27702696 |
| Schrank S et al. | Pore blocking: An innovative formulation strategy for the design of alcohol resistant multi-particulate dosage forms. | 2016 | Int J Pharm | pmid:27282540 |
| Eltayeb M et al. | Electrosprayed nanoparticle delivery system for controlled release. | 2016 | Mater Sci Eng C Mater Biol Appl | pmid:27207047 |
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| Zhao H et al. | Self-assembly of hydrogen-bonded supramolecular complexes of nucleic-acid-base and fatty-acid at the liquid-solid interface. | 2016 | Phys Chem Chem Phys | pmid:27170421 |
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| Haware RV et al. | Vegetable-derived magnesium stearate functionality evaluation by DM(3) approach. | 2016 | Eur J Pharm Sci | pmid:27108117 |
| Wang HJ et al. | Prolongation of the degradation period and improvement of the angiogenesis of zein porous scaffolds in vivo. | 2016 | J Mater Sci Mater Med | pmid:26979976 |
| Cheng CL et al. | Spectral and morphological classification of different chronic and acute Taiwanese gallstones via FTIR, SEM and ESEM-EDX microanalyses. | 2016 | Dig Liver Dis | pmid:26976784 |
| Moazeni M et al. | Time to overcome fluconazole resistant Candida isolates: Solid lipid nanoparticles as a novel antifungal drug delivery system. | 2016 | Colloids Surf B Biointerfaces | pmid:26974361 |
| Lu H et al. | Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway. | 2016 | Diabetologia | pmid:26969487 |
| Thilakarathna SH et al. | Investigations of in vitro bioaccessibility from interesterified stearic and oleic acid-rich blends. | 2016 | Food Funct | pmid:26961726 |
| Michaut A et al. | A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen. | 2016 | Toxicol. Appl. Pharmacol. | pmid:26739624 |
| Ma F et al. | Improvement of β-TCP/PLLA biodegradable material by surface modification with stearic acid. | 2016 | Mater Sci Eng C Mater Biol Appl | pmid:26952440 |
| Zhang C et al. | Design and evaluation of an innovative floating and bioadhesive multiparticulate drug delivery system based on hollow structure. | 2016 | Int J Pharm | pmid:26943975 |
| Zhang Y et al. | CO2/pH-Controllable Viscoelastic Nanostructured Fluid Based on Stearic Acid Soap and Bola-Type Quaternary Ammonium Salt. | 2016 | Langmuir | pmid:26907546 |