stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Mammary Neoplasms, Experimental D008325 67 associated lipids
Melanoma D008545 69 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Alzheimer Disease D000544 76 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Atherosclerosis D050197 85 associated lipids
Arteriosclerosis D001161 86 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Stinton LM and Shaffer EA Epidemiology of gallbladder disease: cholelithiasis and cancer. 2012 Gut Liver pmid:22570746
Abe H and Otsuka M Effects of lubricant-mixing time on prolongation of dissolution time and its prediction by measuring near infrared spectra from tablets. 2012 Drug Dev Ind Pharm pmid:21954869
Zanon NC et al. Immbolization of uricase enzyme in Langmuir and Langmuir-Blodgett films of fatty acids: possible use as a uric acid sensor. 2012 J Colloid Interface Sci pmid:21875709
Sabir A et al. The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.). 2012 J. Sci. Food Agric. pmid:22271548
Vega Mercado F et al. Modulation of the domain topography of biphasic monolayers of stearic acid and dimyristoyl phosphatidylcholine. 2012 Chem. Phys. Lipids pmid:22274694
Morales A et al. Quantitative analysis of hydroperoxy-, keto- and hydroxy-dienes in refined vegetable oils. 2012 J Chromatogr A pmid:22321954
Nussbaum M and Paz Y Ultra-thin SiO2 layers on TiO2: improved photocatalysis by enhancing products' desorption. 2012 Phys Chem Chem Phys pmid:22298253
Ahn BJ et al. Solvent-free acid-catalyzed ring-opening of epoxidized oleochemicals using stearates/stearic acid, and its applications. 2012 J. Agric. Food Chem. pmid:22304525
Liu X et al. Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. 2012 PLoS Pathog. pmid:22412372
Li D et al. Ruminal microbe of biohydrogenation of trans-vaccenic acid to stearic acid in vitro. 2012 BMC Res Notes pmid:22336099
Lee AL and Kim CB The effect of erythromycin on gastrointestinal motility in subtotal gastrectomized patients. 2012 J Korean Surg Soc pmid:22403748
Aling J and Podczeck F The filling of powdered herbs into two-piece hard capsules using hydrogenated cotton seed oil as lubricant. 2012 Eur J Pharm Sci pmid:22960627
Visioli F et al. Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response. 2012 Front Physiol pmid:22393325
Qu J et al. Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. 2012 Biotechnol Biofuels pmid:22377043
Kottala N et al. Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets. 2012 AAPS PharmSciTech pmid:22965660
Som I et al. Status of surfactants as penetration enhancers in transdermal drug delivery. 2012 J Pharm Bioallied Sci pmid:22368393
Sampey BP et al. Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. 2012 PLoS ONE pmid:22701716
Al-Ghamdi AF et al. Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. 2012 Chem Cent J pmid:22353684
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Walash MI et al. Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. 2012 Chem Cent J pmid:22333299
Craig OE et al. Distinguishing wild ruminant lipids by gas chromatography/combustion/isotope ratio mass spectrometry. 2012 Rapid Commun. Mass Spectrom. pmid:22956328
Ahn J et al. Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet. 2012 Mol Nutr Food Res pmid:22968990
Darwish IA et al. Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate. 2012 Chem Cent J pmid:22305461
Ghanam RH et al. Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. 2012 Front Microbiol pmid:22363329
Basseri S and Austin RC Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. 2012 Biochem Res Int pmid:22195283
Seeliger JC et al. Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. 2012 J. Biol. Chem. pmid:22194604
Hao J et al. Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. 2012 Eur J Pharm Sci pmid:22820033
Rozema E et al. Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. 2012 Evid Based Complement Alternat Med pmid:22675394
Severino P et al. Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. 2012 J Drug Deliv pmid:22175030
Han K et al. Novel gene transfer vectors based on artificial recombinant multi-functional oligopeptides. 2012 Int J Pharm pmid:22796172
Kottala N et al. Influence of compaction properties and interfacial topography on the performance of bilayer tablets. 2012 Int J Pharm pmid:22728259
Chansela P et al. Composition and localization of lipids in Penaeus merguiensis ovaries during the ovarian maturation cycle as revealed by imaging mass spectrometry. 2012 PLoS ONE pmid:22432001
Xie YT et al. Brain-targeting study of stearic acid-grafted chitosan micelle drug-delivery system. 2012 Int J Nanomedicine pmid:22802685
Sharma A and Chauhan RS In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. 2012 Comp. Funct. Genomics pmid:22312320
El Semary NA The antimicrobial profile of extracts of a Phormidium-like cyanobacterium changes with phosphate levels. 2012 World J. Microbiol. Biotechnol. pmid:22806854
Patel K et al. Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design. 2012 AAPS PharmSciTech pmid:22167415
Busignies V et al. Prediction of the compressibility of complex mixtures of pharmaceutical powders. 2012 Int J Pharm pmid:22759643
Jubie S et al. Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. 2012 Eur J Med Chem pmid:22770606
Zhang J et al. Synthesis of NaYF(4):Yb/Er/Gd up-conversion luminescent nanoparticles and luminescence resonance energy transfer-based protein detection. 2012 Anal. Biochem. pmid:22155069
Krogager TP et al. Identification of a potential biomarker panel for the intake of the common dietary trans fat elaidic acid (trans∆9-C18:1). 2012 J Proteomics pmid:22483997
Pawar AA et al. Influence of precursor solvent properties on matrix crystallinity and drug release rates from nanoparticle aerosol lipid matrices. 2012 Int J Pharm pmid:22469694
Zhu S et al. Lysosomal delivery of a lipophilic gemcitabine prodrug using novel acid-sensitive micelles improved its antitumor activity. 2012 Bioconjug. Chem. pmid:22471294
Wajid NA and Halpern BP Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. 2012 Chem. Senses pmid:22459162
Gröblacher B et al. Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis. 2012 Bioorg. Med. Chem. pmid:22459211
Nakagawa H et al. Evaluation of infrared-reflection absorption spectroscopy measurement and locally weighted partial least-squares for rapid analysis of residual drug substances in cleaning processes. 2012 Anal. Chem. pmid:22449097
Ménard N et al. Novel surfactants with diglutamic acid polar head group: drug solubilization and toxicity studies. 2012 Pharm. Res. pmid:22451248
Kakisaka K et al. Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21995961
Galvao TF et al. High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects. 2012 Cardiovasc. Res. pmid:21960686
Tumen I et al. A therapeutic approach for wound healing by using essential oils of cupressus and juniperus species growing in Turkey. 2012 Evid Based Complement Alternat Med pmid:21941588
Zhang ZH et al. Solid lipid nanoparticles modified with stearic acid-octaarginine for oral administration of insulin. 2012 Int J Nanomedicine pmid:22848162
Liu J et al. Stearoyl-acyl carrier protein desaturase gene from the oleaginous microalga Chlorella zofingiensis: cloning, characterization and transcriptional analysis. 2012 Planta pmid:22855030
Carol D et al. Synergistic effect of calcium stearate and photo treatment on the rate of biodegradation of low density polyethylene spent saline vials. 2012 Indian J. Exp. Biol. pmid:22822530
Zeng XJ et al. [Chemical constituents of Berchemia lineate]. 2012 Zhong Yao Cai pmid:22822666
Hu FQ et al. pH triggered doxorubicin delivery of PEGylated glycolipid conjugate micelles for tumor targeting therapy. 2012 Mol. Pharm. pmid:22827551
Sellami M et al. Enzymatic transesterification of palm stearin and olein blends to produce zero-trans margarine fat. 2012 BMC Biotechnol. pmid:22889174
Li Y et al. New bactericidal surgical suture coating. 2012 Langmuir pmid:22877364
Das SC and Stewart PJ Characterising surface energy of pharmaceutical powders by inverse gas chromatography at finite dilution. 2012 J. Pharm. Pharmacol. pmid:22881445
Serra Bonvehi J and Orantes Bermejo FJ Detection of adulterated commercial Spanish beeswax. 2012 Food Chem pmid:26434344
Lou CW et al. PLA/ β-TCP complex tubes: the mechanical properties and applications of artificial bone. 2012 J Biomater Sci Polym Ed pmid:21968651
Varshosaz J et al. Optimization of self-assembling properties of fatty acids grafted to methoxy poly(ethylene glycol) as nanocarriers for etoposide. 2012 Acta Pharm pmid:22472447
Wang YN et al. [Study on chemical constituents from Anoectochilus chapaensis]. 2012 Zhong Yao Cai pmid:23236826
Hu SY et al. [Studies on sustained release solid dispersion of tripterine carried by HPMC-stearic acid]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23311152
Yavuz B et al. An overview on dry eye treatment: approaches for cyclosporin a delivery. 2012 ScientificWorldJournal pmid:22619624
Lee SH et al. End point determination of blending process for trimebutine tablets using principle component analysis (PCA) and partial least squares (PLS) regression. 2012 Arch. Pharm. Res. pmid:23054717
Osmond G et al. Metal stearate distributions in modern artists' oil paints: surface and cross-sectional investigation of reference paint films using conventional and synchrotron infrared microspectroscopy. 2012 Appl Spectrosc pmid:23031696
McNamee CE et al. Effect of the degree of dissociation of molecules in a monolayer at an air/water interface on the force between the monolayer and a like-charged particle in the subphase. 2012 J Phys Chem B pmid:23092192
Chu BB et al. [XANES study of lead speciation in duckweed]. 2012 Guang Pu Xue Yu Guang Pu Fen Xi pmid:23016367
Sharma P et al. Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies. 2012 J Biomed Nanotechnol pmid:23030001
Pijls BG et al. Differences in long-term fixation between mobile-bearing and fixed-bearing knee prostheses at ten to 12 years' follow-up: a single-blinded randomised controlled radiostereometric trial. 2012 J Bone Joint Surg Br pmid:23015562
Guzzi R et al. Dynamics and binding affinity of spin-labeled stearic acids in β-lactoglobulin: evidences from EPR spectroscopy and molecular dynamics simulation. 2012 J Phys Chem B pmid:22950964
Charpentier PA et al. Nano-TiO2/polyurethane composites for antibacterial and self-cleaning coatings. 2012 Nanotechnology pmid:23037881
de Jong S et al. A semipermanent coating for preventing protein adsorption at physiological pH in kinetic capillary electrophoresis. 2012 Electrophoresis pmid:22899267
Dziewulska A et al. Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle. 2012 Mol. Membr. Biol. pmid:22881371
Zhang WY et al. Chronic unpredictable mild stress affects myocardial metabolic profiling of SD rats. 2012 J Pharm Biomed Anal pmid:22658902
Tuli RA et al. Studies on the effect of the size of polycaprolactone microspheres for the dispersion of salbutamol sulfate from dry powder inhaler formulations. 2012 Pharm. Res. pmid:22584947
Itoh Y and Hasegawa T Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. 2012 J Phys Chem A pmid:22551093
Gellrich V et al. Behavior of perfluorinated compounds in soils during leaching experiments. 2012 Chemosphere pmid:22391048
Muro M et al. Molecular rearrangement in a zinc stearate Langmuir film dependent on a film preparation method studied using polarization-modulation infrared reflection absorption spectroscopy and X-ray absorption fine structure. 2012 J Phys Chem B pmid:22339471
Okoye P et al. To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis. 2012 Drug Dev Ind Pharm pmid:22304483
Baldwin AC et al. A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22436701
Simonsen ME et al. Comparison of methods for evaluation of activity of photocatalytic films. 2012 Environ Sci Pollut Res Int pmid:23054739
Wang X et al. Volatile components of ethanolic extract from broccolini leaves. 2012 Nat. Prod. Res. pmid:21859369
Suo T et al. Fixed-point and stratified analysis of the fine structure and composition of five gallstones with Fourier transform infrared (FT-IR) specular reflection spectroscopy. 2012 Microsc. Res. Tech. pmid:21809418
Mai K et al. Rosiglitazone increases fatty acid Δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo. 2012 Metab. Clin. Exp. pmid:21741058
Dobrzyn P et al. Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation. 2012 Mitochondrion pmid:21664496
Gören AC et al. Fatty acid composition and chemotaxonomic evaluation of species of Stachys. 2012 Nat. Prod. Res. pmid:21859257
Dawes J et al. An investigation into the impact of magnesium stearate on powder feeding during roller compaction. 2012 Drug Dev Ind Pharm pmid:21810064
Smathers RL et al. Characterization of 4-HNE modified L-FABP reveals alterations in structural and functional dynamics. 2012 PLoS ONE pmid:22701647
Foster SP and Anderson KG Synthetic rates of key stored fatty acids in the biosynthesis of sex pheromone in the moth Heliothis virescens. 2012 Insect Biochem. Mol. Biol. pmid:22982110
Xie J et al. Composition of fatty oils from semen ziziphi spinosae and its cardiotonic effect on isolated toad hearts. 2012 Nat. Prod. Res. pmid:21707231
Guo C et al. In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. 2012 J Nanosci Nanotechnol pmid:22523972
Wang L et al. Effect of rare Earth ions on the properties of composites composed of ethylene vinyl acetate copolymer and layered double hydroxides. 2012 PLoS ONE pmid:22693627
Wong RH et al. Chronic effects of a wild green oat extract supplementation on cognitive performance in older adults: a randomised, double-blind, placebo-controlled, crossover trial. 2012 Nutrients pmid:22690320
Bederman I et al. Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:22679004
Bevilacqua A et al. Selection of Yeasts as Starter Cultures for Table Olives: A Step-by-Step Procedure. 2012 Front Microbiol pmid:22666220
Shah KU and Khan GM Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. 2012 ScientificWorldJournal pmid:22649325
Polizzotti BD et al. Intrapericardial delivery of gelfoam enables the targeted delivery of Periostin peptide after myocardial infarction by inducing fibrin clot formation. 2012 PLoS ONE pmid:22590609
Song IS et al. Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. 2012 PLoS ONE pmid:22590580
Ahmed TA et al. Miconazole nitrate oral disintegrating tablets: in vivo performance and stability study. 2012 AAPS PharmSciTech pmid:22585373
Varshosaz J et al. Development and evaluation of a novel pellet-based tablet system for potential colon delivery of budesonide. 2012 J Drug Deliv pmid:22577558