stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Mammary Neoplasms, Experimental D008325 67 associated lipids
Melanoma D008545 69 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Alzheimer Disease D000544 76 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Atherosclerosis D050197 85 associated lipids
Arteriosclerosis D001161 86 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Han GR and Jang CH Detection of heavy-metal ions using liquid crystal droplet patterns modulated by interaction between negatively charged carboxylate and heavy-metal cations. 2014 Talanta pmid:25059128
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Wang J et al. A soybean acyl carrier protein, GmACP, is important for root nodule symbiosis. 2014 Mol. Plant Microbe Interact. pmid:24400939
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Di Vaio C et al. Influence of some environmental factors on drupe maturation and olive oil composition. 2013 J. Sci. Food Agric. pmid:22936522
Ruddle P et al. Effect of a novel mutation in a Δ9-stearoyl-ACP-desaturase on soybean seed oil composition. 2013 Theor. Appl. Genet. pmid:22961205
Horio T et al. Measurement of flowability of lubricated powders by the vibrating tube method. 2013 Drug Dev Ind Pharm pmid:22781029
Intorre F et al. Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. 2013 Int J Food Sci Nutr pmid:22849318
Němcová-Fürstová V et al. Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells. 2013 Cell. Physiol. Biochem. pmid:23466956
He M et al. Controllable stearic acid crystal induced high hydrophobicity on cellulose film surface. 2013 ACS Appl Mater Interfaces pmid:23289586
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Gotoh K et al. Evaluation of removal of model particulate and oily soils from poly(ethylene terephthalate) films by microscopic image analysis. 2013 J Oleo Sci pmid:23391530
Ogata F et al. Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). 2013 J Oleo Sci pmid:23391535
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Fernandes CP et al. Triterpene esters and biological activities from edible fruits of Manilkara subsericea (Mart.) Dubard, Sapotaceae. 2013 Biomed Res Int pmid:23509702
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John CT et al. Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate. 2013 Pharm. Res. pmid:23512680
Stank K and Steckel H Physico-chemical characterisation of surface modified particles for inhalation. 2013 Int J Pharm pmid:23518364
Kumar N et al. Salt dependent stability of stearic acid Langmuir-Blodgett films exposed to aqueous electrolytes. 2013 Langmuir pmid:23565719
Han SH et al. Bioinspired self-assembled peptide nanofibers with thermostable multivalent α-helices. 2013 Biomacromolecules pmid:23550841
Osorio JG and Muzzio FJ Effects of powder flow properties on capsule filling weight uniformity. 2013 Drug Dev Ind Pharm pmid:23902366
Vadakkan MV et al. Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage. 2013 Int J Nanomedicine pmid:23990716
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Hagen RM et al. Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent. 2013 Anticancer Res. pmid:24123008
Guo H et al. Self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates for delivery of doxorubicin. 2013 Int J Pharm pmid:24140544
Cvetković Z et al. Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. 2013 Med. Oncol. pmid:24085546
Jin Q et al. A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound. 2013 PLoS ONE pmid:24086748
Eltayeb M et al. Electrosprayed core-shell polymer-lipid nanoparticles for active component delivery. 2013 Nanotechnology pmid:24164775
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Li P et al. Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. 2013 Cell. Physiol. Biochem. pmid:24335176
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Hosseini A et al. Direct compression of cushion-layered ethyl cellulose-coated extended release pellets into rapidly disintegrating tablets without changes in the release profile. 2013 Int J Pharm pmid:23892153
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