| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Qi B et al. | A Golgi and tonoplast localized S-acyl transferase is involved in cell expansion, cell division, vascular patterning and fertility in Arabidopsis. | 2013 | New Phytol. | pmid:23795888 |
| Podczeck F et al. | Investigations into the tensile failure of doubly-convex cylindrical tablets under diametral loading using finite element methodology. | 2013 | Int J Pharm | pmid:23834836 |
| Wang N et al. | The mechanism of hydrogen sulfide adsorption on fine rubber particle media (FRPM). | 2013 | J. Hazard. Mater. | pmid:23876257 |
| Mohamed IO | Lipase-catalyzed acidolysis of palm mid fraction oil with palmitic and stearic Fatty Acid mixture for production of cocoa butter equivalent. | 2013 | Appl. Biochem. Biotechnol. | pmid:23877586 |
| Vitturi DA et al. | Modulation of nitro-fatty acid signaling: prostaglandin reductase-1 is a nitroalkene reductase. | 2013 | J. Biol. Chem. | pmid:23878198 |
| Saeedi Vahdat A et al. | Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets. | 2013 | Int J Pharm | pmid:23820132 |
| Zhou QT et al. | Effect of surface coating with magnesium stearate via mechanical dry powder coating approach on the aerosol performance of micronized drug powders from dry powder inhalers. | 2013 | AAPS PharmSciTech | pmid:23196863 |
| Van Hoeck V et al. | Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights. | 2013 | Reproduction | pmid:23108110 |
| Negi JS et al. | Development of solid lipid nanoparticles (SLNs) of lopinavir using hot self nano-emulsification (SNE) technique. | 2013 | Eur J Pharm Sci | pmid:23153618 |
| Nakagawa H et al. | Real-time monitoring of lubrication properties of magnesium stearate using NIR spectrometer and thermal effusivity sensor. | 2013 | Int J Pharm | pmid:23174413 |
| Otsuka Y et al. | Effects of polymorphic transformation on pharmaceutical properties of direct compressed tablets containing theophylline anhydrate bulk powder under high humidity. | 2013 | Colloids Surf B Biointerfaces | pmid:23178204 |
| Schrank S et al. | Microstructure of calcium stearate matrix pellets: a function of the drying process. | 2013 | J Pharm Sci | pmid:23983150 |
| Yang C et al. | Production of aviation fuel via catalytic hydrothermal decarboxylation of fatty acids in microalgae oil. | 2013 | Bioresour. Technol. | pmid:23973977 |
| Barber E et al. | Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24012207 |
| Cunha TA et al. | Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. | 2013 | AAPS PharmSciTech | pmid:23897034 |
| Zhang W et al. | Stearylated antimicrobial peptide melittin and its retro isomer for efficient gene transfection. | 2013 | Bioconjug. Chem. | pmid:24107137 |
| Saroja C and Lakshmi PK | Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. | 2013 | Acta Pharm | pmid:23482314 |
| Kwan HY et al. | The anticancer effect of oridonin is mediated by fatty acid synthase suppression in human colorectal cancer cells. | 2013 | J. Gastroenterol. | pmid:22722903 |
| Tammaro A et al. | Magnesium stearate: an underestimated allergen. | 2012 Oct-Dec | J. Biol. Regul. Homeost. Agents | pmid:23241129 |
| Hentzschel CM et al. | Comparison of traditional and novel tableting excipients: physical and compaction properties. | 2012 Nov-Dec | Pharm Dev Technol | pmid:21740091 |
| Khan FN and Dehghan MH | Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. | 2012 Jan-Mar | Sci Pharm | pmid:22396916 |
| Pujeri SS et al. | Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. | 2012 Jan-Mar | Sci Pharm | pmid:22396908 |
| Anderson EK et al. | Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. | 2012 | Arterioscler. Thromb. Vasc. Biol. | pmid:22556332 |
| Baratta F et al. | Diffusion of counterfeit drugs in developing countries and stability of galenics stored for months under different conditions of temperature and relative humidity. | 2012 | Croat. Med. J. | pmid:22522996 |
| Kwon Y et al. | Arabidopsis serine decarboxylase mutants implicate the roles of ethanolamine in plant growth and development. | 2012 | Int J Mol Sci | pmid:22489147 |
| Arya A et al. | Chloroform Fraction of Centratherum anthelminticum (L.) Seed Inhibits Tumor Necrosis Factor Alpha and Exhibits Pleotropic Bioactivities: Inhibitory Role in Human Tumor Cells. | 2012 | Evid Based Complement Alternat Med | pmid:22474512 |
| Milicic A et al. | Small cationic DDA:TDB liposomes as protein vaccine adjuvants obviate the need for TLR agonists in inducing cellular and humoral responses. | 2012 | PLoS ONE | pmid:22470545 |
| Imae R et al. | LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice. | 2012 | J. Lipid Res. | pmid:22172515 |
| Becker S et al. | Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity. | 2012 | Cancer Biother. Radiopharm. | pmid:22149684 |
| Stryjecki C et al. | Enzymatic activity and genetic variation in SCD1 modulate the relationship between fatty acids and inflammation. | 2012 | Mol. Genet. Metab. | pmid:22209225 |
| Casiraghi A et al. | The influence of the polar head and the hydrophobic chain on the skin penetration enhancement effect of poly(ethylene glycol) derivatives. | 2012 | AAPS PharmSciTech | pmid:22232021 |
| Wei CC and Ge ZQ | Influence of electrolyte and poloxamer 188 on the aggregation kinetics of solid lipid nanoparticles (SLNs). | 2012 | Drug Dev Ind Pharm | pmid:22181005 |
| Reddy KR et al. | Rationale, challenges, and participants in a Phase II trial of a botanical product for chronic hepatitis C. | 2012 | Clin Trials | pmid:22058086 |
| Ruiz M et al. | A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. | 2012 | PLoS ONE | pmid:23056435 |
| Feugmo CG et al. | Towards modelling the vibrational signatures of functionalized surfaces: carboxylic acids on H-Si(111) surfaces. | 2012 | J Phys Condens Matter | pmid:22394578 |
| Watanabe Y et al. | The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation. | 2012 | Diabetes | pmid:22396206 |
| Choi du H et al. | A new experimental design method to optimize formulations focusing on a lubricant for hydrophilic matrix tablets. | 2012 | Drug Dev Ind Pharm | pmid:22348254 |
| Kim DH et al. | Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function. | 2012 | Colloids Surf B Biointerfaces | pmid:22361356 |
| Trupp M et al. | Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. | 2012 | PLoS ONE | pmid:22808006 |
| Schreiber R et al. | Retinyl ester hydrolases and their roles in vitamin A homeostasis. | 2012 | Biochim. Biophys. Acta | pmid:21586336 |
| Bonaduce I et al. | New insights into the ageing of linseed oil paint binder: a qualitative and quantitative analytical study. | 2012 | PLoS ONE | pmid:23166642 |
| Kurotani K et al. | High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. | 2012 | Nutr Res | pmid:23084639 |
| Jung HA and Augsburger LL | Application of a novel automatic disintegration apparatus for the development and evaluation of a direct compression rapidly disintegrating tablet. | 2012 | Drug Dev Ind Pharm | pmid:22091970 |
| Weiss VM et al. | Poly(glycerol adipate)-fatty acid esters as versatile nanocarriers: From nanocubes over ellipsoids to nanospheres. | 2012 | J Control Release | pmid:21971295 |
| Tokudome Y and Otsuka M | Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. | 2012 | Biol. Pharm. Bull. | pmid:22975500 |
| Lu J et al. | A molecular mechanism for modulating plasma Zn speciation by fatty acids. | 2012 | J. Am. Chem. Soc. | pmid:22239162 |
| Nesarikar VV et al. | Instrumented roll technology for the design space development of roller compaction process. | 2012 | Int J Pharm | pmid:22286023 |
| Toubiana D et al. | Metabolic profiling of a mapping population exposes new insights in the regulation of seed metabolism and seed, fruit, and plant relations. | 2012 | PLoS Genet. | pmid:22479206 |
| Eili M et al. | Degradability enhancement of poly(lactic acid) by stearate-Zn(3)Al LDH nanolayers. | 2012 | Int J Mol Sci | pmid:22942682 |
| Loutelier-Bourhis C et al. | Mechanistic study of maleic anhydride grafting onto fatty double bonds using mass spectrometry. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22555920 |