stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Boutonneuse Fever D001907 5 associated lipids
Foreign Bodies D005547 5 associated lipids
Chancroid D002602 4 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Ragnarsson G and Sjögren J Force-displacement measurements in tableting. 1985 J. Pharm. Pharmacol. pmid:2858558
Esezobo S The effect of some excipients on the physical properties of a paracetamol tablet formulation. 1985 J. Pharm. Pharmacol. pmid:2858567
Zoeller RA and Wood R The importance of the stearoyl-CoA desaturase system in octadecenoate metabolism in the Morris hepatoma 7288C. 1985 Biochim. Biophys. Acta pmid:2860925
Bangudu AB and Pilpel N Effects of composition, moisture and stearic acid on the plasto-elasticity and tableting of paracetamol-microcrystalline cellulose mixtures. 1985 J. Pharm. Pharmacol. pmid:2862234
Yasuda H et al. Biphasic liberation of arachidonic and stearic acids during cerebral ischemia. 1985 J. Neurochem. pmid:2987409
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Politi LE et al. Dexamethasone effect on free fatty acid and diacylglycerol accumulation during experimentally induced vasogenic brain edema. 1985 Neurochem Pathol pmid:3831846
Johansson ME Investigations of the mixing time dependence of the lubricating properties of granular and powdered magnesium stearate. 1985 Acta Pharm. Suec. pmid:3832785
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Habenicht AJ et al. Cell cycle-dependent changes in arachidonic acid and glycerol metabolism in Swiss 3T3 cells stimulated by platelet-derived growth factor. 1985 J. Biol. Chem. pmid:3918038
Noble RC and Shand JH Unsaturated fatty acid compositional changes and desaturation during the embryonic development of the chicken (Gallus domesticus). 1985 Lipids pmid:3925271
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Hegde RP et al. Studies of powder flow using a recording powder flowmeter and measurement of the dynamic angle of repose. 1985 J Pharm Sci pmid:3981409
Uribe WR Yaws in Colombia. 1985 May-Jun Rev. Infect. Dis. pmid:4012172
Willcox RR Mass treatment campaigns against the endemic treponematoses. 1985 May-Jun Rev. Infect. Dis. pmid:4012173
Brown ST Therapy for nonvenereal treponematoses: review of the efficacy of penicillin and consideration of alternatives. 1985 May-Jun Rev. Infect. Dis. pmid:4012176
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Dudley DT and Spector AA Inositol phospholipid arachidonic acid metabolism in GH3 pituitary cells. 1986 Biochem. J. pmid:3098231
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Oh-Hashi Y et al. Temperature- and growth-phase-dependent changes in membrane fatty acid compositions of Brevibacterium ammoniagenes. 1986 Arch. Biochem. Biophys. pmid:3729431
Carter-Dawson L et al. Rhodopsin, 11-cis vitamin A, and interstitial retinol-binding protein (IRBP) during retinal development in normal and rd mutant mice. 1986 Dev. Biol. pmid:3732615
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Fujii T et al. Effect of exogenous lipids incorporated into the membrane of human erythrocytes on its glucose transport activity. 1986 Biochem. Int. pmid:3741447
Chester DW et al. The influence of saturated fatty acid modulation of bilayer physical state on cellular and membrane structure and function. 1986 Biochim. Biophys. Acta pmid:3741857
Tsao FH Selective use of palmitic acid over stearic acid for synthesis of phosphatidylcholine and phosphatidylglycerol in lung. 1986 Lipids pmid:3796238
Muñoz-Espin T et al. Erythromycin versus tetracycline for treatment of Mediterranean spotted fever. 1986 Arch. Dis. Child. pmid:3535687
Sakaguchi M et al. Effects of dietary saturated and unsaturated fatty acids on fecal bile acids and colon carcinogenesis induced by azoxymethane in rats. 1986 Cancer Res. pmid:3940210
Bankson DD et al. Determination of retinyl esters and retinol in serum or plasma by normal-phase liquid chromatography: method and applications. 1986 Clin. Chem. pmid:3940733
Yamamoto O Radiation-induced crosslinks between carboxylic acids and compounds of biological interest. 1986 Radiat. Res. pmid:3952268
Siegel I et al. Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. 1986 Fertil. Steril. pmid:2868925
Johansson ME and Nicklasson M Investigation of the film formation of magnesium stearate by applying a flow-through dissolution technique. 1986 J. Pharm. Pharmacol. pmid:2869127
Tabachnick M and Korcek L Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. 1986 Biochim. Biophys. Acta pmid:2869786