stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Skin Diseases, Infectious D012874 7 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Tenosynovitis D013717 3 associated lipids
Thrombosis D013927 49 associated lipids
Tremor D014202 15 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Urethritis D014526 9 associated lipids
Urticaria D014581 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
el-Sharkawy SH et al. Microbiological transformations of lipids: acyl-specific hydrolysis of lard by yeasts. 1993 Appl. Environ. Microbiol. pmid:8480999
Woldseth B et al. Incorporation of stearic acid (18:0) and palmitic acid (16:0) in phospholipid molecular species studied in isolated rat liver cells. 1993 Biochim. Biophys. Acta pmid:8481391
Doering TL et al. Trypanosome metabolism of myristate, the fatty acid required for the variant surface glycoprotein membrane anchor. 1993 J. Biol. Chem. pmid:8486622
Mustad VA et al. Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. 1993 Metab. Clin. Exp. pmid:8487669
Sastri MS et al. In vitro and in vivo studies on slow release propranolol hydrochloride suppositories. Pharmacokinetic and pharmacodynamic evaluation. 1993 Arzneimittelforschung pmid:8489559
Sylvester PW et al. Effects of specific fatty acids on prolactin-induced NB2 lymphoma cell proliferation. 1993 Life Sci. pmid:8505862
Melik-Nubarov NS et al. Interaction of hydrophobized antiviral antibodies with influenza virus infected MDCK cells. 1993 Biochem. Mol. Biol. Int. pmid:8508145
Cárdenas L et al. Isolation, chemical structures and biological activity of the lipo-chitin oligosaccharide nodulation signals from Rhizobium etli. 1995 Plant Mol. Biol. pmid:8534845
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Lin HH et al. Increased norfloxacin skin permeability for fatty alcohol propylene glycol (FAPG) ointment by optimized process of preparation: behavior of stearic acid in stratum corneum lipids. 1995 Biol. Pharm. Bull. pmid:8593480
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Blaha CD et al. Improved electrochemical properties of stearate-graphite paste electrodes after albumin and phospholipid treatments. 1996 Biosens Bioelectron pmid:8600916
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Bruce JS and Salter AM Metabolic fate of oleic acid, palmitic acid and stearic acid in cultured hamster hepatocytes. 1996 Biochem. J. pmid:8670161
van Greevenbroek MM et al. Effects of saturated, mono-, and polyunsaturated fatty acids on the secretion of apo B containing lipoproteins by Caco-2 cells. 1996 Atherosclerosis pmid:8678919
Tholstrup T et al. Acute effect of high-fat meals rich in either stearic or myristic acid on hemostatic factors in healthy young men. 1996 Am. J. Clin. Nutr. pmid:8694016
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Lassus A et al. Erythromycin and lymecycline treatment in chlamydia-positive and Chlamydia-negative non-gonococcal urethritis--a partner-controlled study. 1979 Acta Derm. Venereol. pmid:87096
Sherrington EJ et al. Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. 1996 Biochem. Soc. Trans. pmid:8736816
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Shu R et al. [Chemical constituents of Cyclocarya paliurus (Batal.) Iljinsk]. 1995 Zhongguo Zhong Yao Za Zhi pmid:8737472
Mansbach CM The origin of chylomicron phosphatidylcholine in the rat. 1977 J. Clin. Invest. pmid:874099
Veit M et al. Cytoplasmic tail length influences fatty acid selection for acylation of viral glycoproteins. 1996 Biochem. J. pmid:8761467
Schmidt-Weber CB et al. Apoptotic cell death in activated monocytes following incorporation of clodronate-liposomes. 1996 J. Leukoc. Biol. pmid:8773585
Zakhariv OIa and Ianovich VG [The utilization of [9,10-(3)H] stearic and [1-(14)C] linolenic acids in the in-vitro synthesis of lipids in ruminant tissues]. 1995 Jul-Aug Zh. Evol. Biokhim. Fiziol. pmid:8779280
Hughes TA et al. Comparative lipoprotein metabolism of myristate, palmitate, and stearate in normolipidemic men. 1996 Metab. Clin. Exp. pmid:8781298
Negash S et al. Phosphorylation of phospholamban by cAMP-dependent protein kinase enhances interactions between Ca-ATPase polypeptide chains in cardiac sarcoplasmic reticulum membranes. 1996 Biochemistry pmid:8784178
Mastronicolis SK et al. Diversity of the polar lipids of the food-borne pathogen Listeria monocytogenes. 1996 Lipids pmid:8784744
Reverey H et al. Differential fatty acid selection during biosynthetic S-acylation of a transmembrane protein (HEF) and other proteins in insect cells (Sf9) and in mammalian cells (CV1). 1996 J. Biol. Chem. pmid:8798573
Kirsch AJ et al. Effects of diode laser welding with dye-enhanced glue on tensile strength of sutures commonly used in urology. 1996 Lasers Surg Med pmid:8833285
Pai T and Yeh YY Stearic acid unlike shorter-chain saturated fatty acids is poorly utilized for triacylglycerol synthesis and beta-oxidation in cultured rat hepatocytes. 1996 Lipids pmid:8835403
Gotoh N et al. Inhibition of oxidation of low density lipoprotein by vitamin E and related compounds. 1996 Free Radic. Res. pmid:8845913
Shetty HU et al. Identification of two molecular species of rat brain phosphatidylcholine that rapidly incorporate and turn over arachidonic acid in vivo. 1996 J. Neurochem. pmid:8858956
Uchida T et al. Microencapsulation of ovalbumin in poly(lactide-co-glycolide) by an oil-in-oil (o/o) solvent evaporation method. 1996 Sep-Oct J Microencapsul pmid:8864988
Murkovic M et al. Variability of fatty acid content in pumpkin seeds (Cucurbita pepo L.). 1996 Z Lebensm Unters Forsch pmid:8873459
Wargo DJ and Drennen JK Near-infrared spectroscopic characterization of pharmaceutical powder blends. 1996 J Pharm Biomed Anal pmid:8877847
Peck MD et al. Fatty acid unsaturation increases expression and capping of murine lymphocyte CD44 and CD45. 1996 Nutrition pmid:8878171