| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Legionnaires' Disease | D007877 | 4 associated lipids |
| Whooping Cough | D014917 | 6 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Anderson EK et al. | Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. | 2012 | Arterioscler. Thromb. Vasc. Biol. | pmid:22556332 |
| Visioli F et al. | Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response. | 2012 | Front Physiol | pmid:22393325 |
| Qu J et al. | Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. | 2012 | Biotechnol Biofuels | pmid:22377043 |
| Som I et al. | Status of surfactants as penetration enhancers in transdermal drug delivery. | 2012 | J Pharm Bioallied Sci | pmid:22368393 |
| Al-Ghamdi AF et al. | Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. | 2012 | Chem Cent J | pmid:22353684 |
| Walash MI et al. | Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. | 2012 | Chem Cent J | pmid:22333299 |
| Ghadiri M et al. | Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size. | 2012 | Int J Pharm | pmid:22227603 |
| Borbon IA et al. | Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1. | 2012 | Pharmacol. Biochem. Behav. | pmid:22202649 |
| Scalia S et al. | Preparation and in vitro evaluation of salbutamol-loaded lipid microparticles for sustained release pulmonary therapy. | 2012 | J Microencapsul | pmid:22208706 |
| Duong CT and Roper MG | A microfluidic device for the automated derivatization of free fatty acids to fatty acid methyl esters. | 2012 | Analyst | pmid:22166918 |
| Imae R et al. | LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice. | 2012 | J. Lipid Res. | pmid:22172515 |
| Becker S et al. | Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity. | 2012 | Cancer Biother. Radiopharm. | pmid:22149684 |
| Stryjecki C et al. | Enzymatic activity and genetic variation in SCD1 modulate the relationship between fatty acids and inflammation. | 2012 | Mol. Genet. Metab. | pmid:22209225 |
| Wei CC and Ge ZQ | Influence of electrolyte and poloxamer 188 on the aggregation kinetics of solid lipid nanoparticles (SLNs). | 2012 | Drug Dev Ind Pharm | pmid:22181005 |
| Ghanam RH et al. | Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. | 2012 | Front Microbiol | pmid:22363329 |
| Rozema E et al. | Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. | 2012 | Evid Based Complement Alternat Med | pmid:22675394 |
| Sharma A and Chauhan RS | In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. | 2012 | Comp. Funct. Genomics | pmid:22312320 |
| Patel K et al. | Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design. | 2012 | AAPS PharmSciTech | pmid:22167415 |
| Zhang J et al. | Synthesis of NaYF(4):Yb/Er/Gd up-conversion luminescent nanoparticles and luminescence resonance energy transfer-based protein detection. | 2012 | Anal. Biochem. | pmid:22155069 |
| Griffith EC et al. | Hydrophobic collapse of a stearic acid film by adsorbed l-phenylalanine at the air-water interface. | 2012 | J Phys Chem B | pmid:22691061 |
| Harvey KA et al. | Trans fatty acids: induction of a pro-inflammatory phenotype in endothelial cells. | 2012 | Lipids | pmid:22684911 |
| Mekhail GM et al. | Anticancer effect of atorvastatin nanostructured polymeric micelles based on stearyl-grafted chitosan. | 2012 | Int. J. Biol. Macromol. | pmid:22652220 |
| Feugmo CG et al. | Towards modelling the vibrational signatures of functionalized surfaces: carboxylic acids on H-Si(111) surfaces. | 2012 | J Phys Condens Matter | pmid:22394578 |
| Tumen I et al. | A therapeutic approach for wound healing by using essential oils of cupressus and juniperus species growing in Turkey. | 2012 | Evid Based Complement Alternat Med | pmid:21941588 |
| Watanabe Y et al. | The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation. | 2012 | Diabetes | pmid:22396206 |
| Choi du H et al. | A new experimental design method to optimize formulations focusing on a lubricant for hydrophilic matrix tablets. | 2012 | Drug Dev Ind Pharm | pmid:22348254 |
| Kim DH et al. | Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function. | 2012 | Colloids Surf B Biointerfaces | pmid:22361356 |
| Yavuz B et al. | An overview on dry eye treatment: approaches for cyclosporin a delivery. | 2012 | ScientificWorldJournal | pmid:22619624 |
| Bonaduce I et al. | New insights into the ageing of linseed oil paint binder: a qualitative and quantitative analytical study. | 2012 | PLoS ONE | pmid:23166642 |
| Kurotani K et al. | High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. | 2012 | Nutr Res | pmid:23084639 |
| Zhang WY et al. | Chronic unpredictable mild stress affects myocardial metabolic profiling of SD rats. | 2012 | J Pharm Biomed Anal | pmid:22658902 |
| Tuli RA et al. | Studies on the effect of the size of polycaprolactone microspheres for the dispersion of salbutamol sulfate from dry powder inhaler formulations. | 2012 | Pharm. Res. | pmid:22584947 |
| Itoh Y and Hasegawa T | Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. | 2012 | J Phys Chem A | pmid:22551093 |
| Gellrich V et al. | Behavior of perfluorinated compounds in soils during leaching experiments. | 2012 | Chemosphere | pmid:22391048 |
| Muro M et al. | Molecular rearrangement in a zinc stearate Langmuir film dependent on a film preparation method studied using polarization-modulation infrared reflection absorption spectroscopy and X-ray absorption fine structure. | 2012 | J Phys Chem B | pmid:22339471 |
| Okoye P et al. | To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis. | 2012 | Drug Dev Ind Pharm | pmid:22304483 |
| Dobrzyn P et al. | Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation. | 2012 | Mitochondrion | pmid:21664496 |
| Wang Z et al. | Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling. | 2012 | Br. J. Nutr. | pmid:21733316 |
| Nesarikar VV et al. | Instrumented roll technology for the design space development of roller compaction process. | 2012 | Int J Pharm | pmid:22286023 |
| Guo C et al. | In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. | 2012 | J Nanosci Nanotechnol | pmid:22523972 |
| Bederman I et al. | Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice. | 2012 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:22679004 |
| Bevilacqua A et al. | Selection of Yeasts as Starter Cultures for Table Olives: A Step-by-Step Procedure. | 2012 | Front Microbiol | pmid:22666220 |
| Chakradhar RP and Dinesh Kumar V | Water-repellent coatings prepared by modification of ZnO nanoparticles. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22575349 |
| Shah KU and Khan GM | Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. | 2012 | ScientificWorldJournal | pmid:22649325 |
| Agostini F et al. | Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. | 2012 | ScientificWorldJournal | pmid:22593706 |
| Polizzotti BD et al. | Intrapericardial delivery of gelfoam enables the targeted delivery of Periostin peptide after myocardial infarction by inducing fibrin clot formation. | 2012 | PLoS ONE | pmid:22590609 |
| Guillon A et al. | Pulmonary delivery of dry powders to rats: tolerability limits of an intra-tracheal administration model. | 2012 | Int J Pharm | pmid:22609125 |
| Song IS et al. | Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. | 2012 | PLoS ONE | pmid:22590580 |
| Schrank S et al. | Ibuprofen-loaded calcium stearate pellets: drying-induced variations in dosage form properties. | 2012 | AAPS PharmSciTech | pmid:22552931 |
| Loutelier-Bourhis C et al. | Mechanistic study of maleic anhydride grafting onto fatty double bonds using mass spectrometry. | 2012 | Rapid Commun. Mass Spectrom. | pmid:22555920 |