stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Cholestasis, Extrahepatic D001651 7 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Infertility D007246 3 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Neutsch L et al. UPEC biomimickry at the urothelial barrier: lectin-functionalized PLGA microparticles for improved intravesical chemotherapy. 2013 Int J Pharm pmid:23628404
Li L et al. Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. 2013 Int J Pharm pmid:23624081
Muzíková J and Sináglová P Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses. 2013 Jan-Feb Acta Pol Pharm pmid:23610968
Li CC et al. [In situ rat intestine absorption of paclitaxel-loaded solid lipid nanoparticles modified with cell-penetrating peptides]. 2013 Yao Xue Xue Bao pmid:23600154
Maia M et al. A novel, direct, reagent-free method for the detection of beeswax adulteration by single-reflection attenuated total reflectance mid-infrared spectroscopy. 2013 Talanta pmid:23598195
Uğurlu T and Halaçoğlu MD Effects of some lubricants and evaluation of compression parameters on directly compressible powders. 2014 Pharm Dev Technol pmid:23590449
Salazar J et al. Application of the combinative particle size reduction technology H 42 to produce fast dissolving glibenclamide tablets. 2013 Eur J Pharm Sci pmid:23587645
Kumar N et al. Salt dependent stability of stearic acid Langmuir-Blodgett films exposed to aqueous electrolytes. 2013 Langmuir pmid:23565719
Han SH et al. Bioinspired self-assembled peptide nanofibers with thermostable multivalent α-helices. 2013 Biomacromolecules pmid:23550841
Kedryna T et al. Pyruvate kinase from cytosolic fractions of the Ehrlich ascites tumour, normal mouse liver and skeletal muscle. 1990 Biochim. Biophys. Acta pmid:2354196
Stank K and Steckel H Physico-chemical characterisation of surface modified particles for inhalation. 2013 Int J Pharm pmid:23518364
John CT et al. Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate. 2013 Pharm. Res. pmid:23512680
You J et al. Specific tumor delivery of paclitaxel using glycolipid-like polymer micelles containing gold nanospheres. 2013 Biomaterials pmid:23510855
Fernandes CP et al. Triterpene esters and biological activities from edible fruits of Manilkara subsericea (Mart.) Dubard, Sapotaceae. 2013 Biomed Res Int pmid:23509702
Saroja C and Lakshmi PK Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. 2013 Acta Pharm pmid:23482314
Risley DS et al. Analysis of magnesium from magnesium stearate in pharmaceutical tablet formulations using hydrophilic interaction liquid chromatography with nano quantity analyte detection. 2013 J Pharm Biomed Anal pmid:23474810
Vervaeck A et al. Prilling of fatty acids as a continuous process for the development of controlled release multiparticulate dosage forms. 2013 Eur J Pharm Biopharm pmid:23474381
Němcová-Fürstová V et al. Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells. 2013 Cell. Physiol. Biochem. pmid:23466956
Mirani ZA and Jamil N Role of extra-cellular fatty acids in vancomycin induced biofilm formation by vancomycin resistant Staphylococcus aureus. 2013 Pak J Pharm Sci pmid:23455211
Sovány T et al. Application of physicochemical properties and process parameters in the development of a neural network model for prediction of tablet characteristics. 2013 AAPS PharmSciTech pmid:23413109
Pethrick RA and Song M Dielectric studies of amylose, amylopectin and amylose-stearic acid complexes. 2013 Carbohydr Polym pmid:23399185
Díaz R et al. Identification of fatty acids in canine seminal plasma. 2014 Andrologia pmid:23398451
Ogata F et al. Study on analysis of waste edible oil with deterioration and removal of acid value, carbonyl value, and free fatty acid by a food additive (calcium silicate). 2013 J Oleo Sci pmid:23391535
Gotoh K et al. Evaluation of removal of model particulate and oily soils from poly(ethylene terephthalate) films by microscopic image analysis. 2013 J Oleo Sci pmid:23391530
Lakio S et al. Challenges in detecting magnesium stearate distribution in tablets. 2013 AAPS PharmSciTech pmid:23378252
Persad RA et al. Erythrocyte stearic to oleic acid ratio in prostatic carcinoma. 1990 Br J Urol pmid:2337746
Wu JH et al. Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. 2013 Circ Cardiovasc Genet pmid:23362303
Arukuusk P et al. New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids. 2013 Biochim. Biophys. Acta pmid:23357356
Ong CN et al. Biological monitoring of workers exposed to lead stearate. 1990 J Appl Toxicol pmid:2335713
Sharma P et al. Structural insights into the dual strategy of recognition by peptidoglycan recognition protein, PGRP-S: structure of the ternary complex of PGRP-S with lipopolysaccharide and stearic acid. 2013 PLoS ONE pmid:23326499
Ishida Y et al. Fatty acid solubilizer from the oral disk of the blowfly. 2013 PLoS ONE pmid:23326317
Järvinen K et al. In-line monitoring of the drug content of powder mixtures and tablets by near-infrared spectroscopy during the continuous direct compression tableting process. 2013 Eur J Pharm Sci pmid:23313622
Hu SY et al. [Studies on sustained release solid dispersion of tripterine carried by HPMC-stearic acid]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23311152
Lee W et al. Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress. 2013 J. Biol. Chem. pmid:23306194
Tükel S et al. Optimization of lipase-catalyzed synthesis of fructose stearate using response surface methodology. 2013 Artif Cells Nanomed Biotechnol pmid:23305558
He M et al. Controllable stearic acid crystal induced high hydrophobicity on cellulose film surface. 2013 ACS Appl Mater Interfaces pmid:23289586
Salehi M et al. Debinding mechanisms in thermoplastic processing of a Ba(0.5)Sr(0.5)Co(0.8)Fe(0.2)O(3-δ)- stearic acid-polystyrene mixture. 2013 ChemSusChem pmid:23281298
Hu P et al. Genotoxicity evaluation of stearic acid grafted chitosan oligosaccharide nanomicelles. 2013 Mutat. Res. pmid:23274307
Wu X et al. Alkanethiol-functionalized terahertz metamaterial as label-free, highly-sensitive and specific biosensor. 2013 Biosens Bioelectron pmid:23261700
Tammaro A et al. Magnesium stearate: an underestimated allergen. 2012 Oct-Dec J. Biol. Regul. Homeost. Agents pmid:23241129
Wang YN et al. [Study on chemical constituents from Anoectochilus chapaensis]. 2012 Zhong Yao Cai pmid:23236826
Wan Q et al. Self-assembled magnetic theranostic nanoparticles for highly sensitive MRI of minicircle DNA delivery. 2013 Nanoscale pmid:23224057
Baek JS and Cho CW 2-Hydroxypropyl-β-cyclodextrin-modified SLN of paclitaxel for overcoming p-glycoprotein function in multidrug-resistant breast cancer cells. 2013 J. Pharm. Pharmacol. pmid:23215690
Dhasaiyan P et al. Influence of the sophorolipid molecular geometry on their self-assembled structures. 2013 Chem Asian J pmid:23208802
Zhou QT et al. Effect of surface coating with magnesium stearate via mechanical dry powder coating approach on the aerosol performance of micronized drug powders from dry powder inhalers. 2013 AAPS PharmSciTech pmid:23196863
Azordegan N et al. Carcinogenesis alters fatty acid profile in breast tissue. 2013 Mol. Cell. Biochem. pmid:23180247
Vijayaraghavan M et al. Suitability of polymer materials for production of pulmonary microparticles using a PGSS supercritical fluid technique: preparation of microparticles using PEG, fatty acids and physical or chemicals blends of PEG and fatty acids. 2013 Int J Pharm pmid:23178217
Otsuka Y et al. Effects of polymorphic transformation on pharmaceutical properties of direct compressed tablets containing theophylline anhydrate bulk powder under high humidity. 2013 Colloids Surf B Biointerfaces pmid:23178204
Nakagawa H et al. Real-time monitoring of lubrication properties of magnesium stearate using NIR spectrometer and thermal effusivity sensor. 2013 Int J Pharm pmid:23174413
Bonaduce I et al. New insights into the ageing of linseed oil paint binder: a qualitative and quantitative analytical study. 2012 PLoS ONE pmid:23166642
Järvinen MA et al. Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release. 2013 Drug Dev Ind Pharm pmid:23163644
Negi JS et al. Development of solid lipid nanoparticles (SLNs) of lopinavir using hot self nano-emulsification (SNE) technique. 2013 Eur J Pharm Sci pmid:23153618
Sharma P et al. Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. 2013 Arch. Biochem. Biophys. pmid:23149273
Van Hoeck V et al. Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights. 2013 Reproduction pmid:23108110
Alakhov VYu AV et al. Increasing cytostatic effects of ricin A chain and Staphylococcus aureus enterotoxin A through in vitro hydrophobization with fatty acid residues. 1990 Biotechnol. Appl. Biochem. pmid:2310510
Neoptolemos JP and Thomas BS Erythrocyte membrane stearic acid: oleic acid ratios in colorectal cancer using tube capillary column gas liquid chromatography. 1990 Ann. Clin. Biochem. pmid:2310156
McNamee CE et al. Effect of the degree of dissociation of molecules in a monolayer at an air/water interface on the force between the monolayer and a like-charged particle in the subphase. 2012 J Phys Chem B pmid:23092192
Delbecq F et al. N-stearoyl amino acid derivatives: potent biomimetic hydro/organogelators as templates for preparation of gold nanoparticles. 2013 J Colloid Interface Sci pmid:23089597
Kurotani K et al. High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. 2012 Nutr Res pmid:23084639
Avalle P et al. Interrogating erosion-based drug liberation phenomena from hydrophilic matrices using near infrared (NIR) spectroscopy. 2013 Eur J Pharm Sci pmid:23059372
Ruiz M et al. A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. 2012 PLoS ONE pmid:23056435
Yuan H et al. Preparation and evaluation of SiO2-deposited stearic acid-g-chitosan nanoparticles for doxorubicin delivery. 2012 Int J Nanomedicine pmid:23055724
Simonsen ME et al. Comparison of methods for evaluation of activity of photocatalytic films. 2012 Environ Sci Pollut Res Int pmid:23054739
Lee SH et al. End point determination of blending process for trimebutine tablets using principle component analysis (PCA) and partial least squares (PLS) regression. 2012 Arch. Pharm. Res. pmid:23054717
Desai SS et al. Methods for reduction of cohesive forces between carrier and drug in DPI formulation. 2013 Drug Dev Ind Pharm pmid:23050727
Charpentier PA et al. Nano-TiO2/polyurethane composites for antibacterial and self-cleaning coatings. 2012 Nanotechnology pmid:23037881
Osmond G et al. Metal stearate distributions in modern artists' oil paints: surface and cross-sectional investigation of reference paint films using conventional and synchrotron infrared microspectroscopy. 2012 Appl Spectrosc pmid:23031696
Sharma P et al. Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies. 2012 J Biomed Nanotechnol pmid:23030001
Chu BB et al. [XANES study of lead speciation in duckweed]. 2012 Guang Pu Xue Yu Guang Pu Fen Xi pmid:23016367
Pijls BG et al. Differences in long-term fixation between mobile-bearing and fixed-bearing knee prostheses at ten to 12 years' follow-up: a single-blinded randomised controlled radiostereometric trial. 2012 J Bone Joint Surg Br pmid:23015562
Aljaberi A et al. Understanding and optimizing the dual excipient functionality of sodium lauryl sulfate in tablet formulation of poorly water soluble drug: wetting and lubrication. 2013 Mar-Apr Pharm Dev Technol pmid:23009028
Leskinen JT et al. Real-time tablet formation monitoring with ultrasound measurements in eccentric single station tablet press. 2013 Int J Pharm pmid:22985771
Foster SP and Anderson KG Synthetic rates of key stored fatty acids in the biosynthesis of sex pheromone in the moth Heliothis virescens. 2012 Insect Biochem. Mol. Biol. pmid:22982110
Tokudome Y and Otsuka M Possibility of alveolar bone promoting enhancement by using lipophilic and/or hydrophilic zinc related compounds in zinc-deficient osteoporosis rats. 2012 Biol. Pharm. Bull. pmid:22975500
Ahn J et al. Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet. 2012 Mol Nutr Food Res pmid:22968990
Chu X et al. Sterol regulatory element-binding protein-1c mediates increase of postprandial stearic acid, a potential target for improving insulin resistance, in hyperlipidemia. 2013 Diabetes pmid:22966071
Kottala N et al. Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets. 2012 AAPS PharmSciTech pmid:22965660
Ruddle P et al. Effect of a novel mutation in a Δ9-stearoyl-ACP-desaturase on soybean seed oil composition. 2013 Theor. Appl. Genet. pmid:22961205
Aling J and Podczeck F The filling of powdered herbs into two-piece hard capsules using hydrogenated cotton seed oil as lubricant. 2012 Eur J Pharm Sci pmid:22960627
Craig OE et al. Distinguishing wild ruminant lipids by gas chromatography/combustion/isotope ratio mass spectrometry. 2012 Rapid Commun. Mass Spectrom. pmid:22956328
Hu FQ et al. Effective antitumor gene therapy delivered by polyethylenimine-conjugated stearic acid-g-chitosan oligosaccharide micelles. 2013 Gene Ther. pmid:22951455
Guzzi R et al. Dynamics and binding affinity of spin-labeled stearic acids in β-lactoglobulin: evidences from EPR spectroscopy and molecular dynamics simulation. 2012 J Phys Chem B pmid:22950964
Eili M et al. Degradability enhancement of poly(lactic acid) by stearate-Zn(3)Al LDH nanolayers. 2012 Int J Mol Sci pmid:22942682
Di Vaio C et al. Influence of some environmental factors on drupe maturation and olive oil composition. 2013 J. Sci. Food Agric. pmid:22936522
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Mazel V et al. The surface layer of pharmaceutical compacts: the role of the punch surface and its impact on the mechanical properties of the compacts. 2013 Int J Pharm pmid:22902389
Ranhotra HS and Sharma R Polyunsaturated fatty acids inhibit mouse hepatic glucocorticoid receptor activation in vitro. 2004 Indian J. Biochem. Biophys. pmid:22900281
de Jong S et al. A semipermanent coating for preventing protein adsorption at physiological pH in kinetic capillary electrophoresis. 2012 Electrophoresis pmid:22899267
Sellami M et al. Enzymatic transesterification of palm stearin and olein blends to produce zero-trans margarine fat. 2012 BMC Biotechnol. pmid:22889174
Das SC and Stewart PJ Characterising surface energy of pharmaceutical powders by inverse gas chromatography at finite dilution. 2012 J. Pharm. Pharmacol. pmid:22881445
Dziewulska A et al. Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle. 2012 Mol. Membr. Biol. pmid:22881371
Hayashi Y et al. Latent structure analysis of the process variables and pharmaceutical responses of an orally disintegrating tablet. 2012 Chem. Pharm. Bull. pmid:22878814
Li Y et al. New bactericidal surgical suture coating. 2012 Langmuir pmid:22877364
Liu J et al. Stearoyl-acyl carrier protein desaturase gene from the oleaginous microalga Chlorella zofingiensis: cloning, characterization and transcriptional analysis. 2012 Planta pmid:22855030
Intorre F et al. Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. 2013 Int J Food Sci Nutr pmid:22849318
Zhang ZH et al. Solid lipid nanoparticles modified with stearic acid-octaarginine for oral administration of insulin. 2012 Int J Nanomedicine pmid:22848162
Hu FQ et al. pH triggered doxorubicin delivery of PEGylated glycolipid conjugate micelles for tumor targeting therapy. 2012 Mol. Pharm. pmid:22827551
Zeng XJ et al. [Chemical constituents of Berchemia lineate]. 2012 Zhong Yao Cai pmid:22822666
Carol D et al. Synergistic effect of calcium stearate and photo treatment on the rate of biodegradation of low density polyethylene spent saline vials. 2012 Indian J. Exp. Biol. pmid:22822530
Hao J et al. Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. 2012 Eur J Pharm Sci pmid:22820033