stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Cholestasis, Extrahepatic D001651 7 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Infertility D007246 3 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
GERSHFELD NL and SHANES AM Antagonism of veratrine by calcium ion in monolayers of stearic acid. 1959 Science pmid:13658972
BLOMSTRAND R et al. Asymmetric incorporation of linoleic acid-1-C14 and stearic acid-1-C14 into human lymph lecithins during fat absorption. 1959 Proc. Soc. Exp. Biol. Med. pmid:13645714
FITZHUGH OG et al. Chronic oral toxicities of four stearic acid emulsifiers. 1959 Toxicol. Appl. Pharmacol. pmid:13659539
HURLEY HJ and SHELLEY WB The colloidal state as a stimulus for non-allergic epithelioid granulomas: experimental studies in man with pure sodium stearate and palmitate. 1959 J. Invest. Dermatol. pmid:14405513
KELLERSHOHN C and BENICHOUX R [Comparative study of the drainage through the lymphatic vessels of a radioactive fat, ethyl diiodosterate labeled with I 131, and a radioactive colloidal substance, colloidal gold 198]. 1958 May-Jun Minerva Nucl pmid:13565747
COX AJ and DEEDS F Dietary production of lipogranuloma in rats. 1958 Mar-Apr Am. J. Pathol. pmid:13520907
LONG CL et al. Studies on absorption and metabolism of propylene glycol distearate. 1958 Arch. Biochem. Biophys. pmid:13584006
LONG CL et al. An investigation of the in vivo hydrolysis and absorption of propylene glycol distearate. 1958 Arch. Biochem. Biophys. pmid:13584007
CONIGLIO JG and CATE DL The distribution and biosynthesis of palmitic and stearic acids in liver, intestine, and carcass of intact normal and fasted rats. 1958 J. Biol. Chem. pmid:13549425
DAWSON RM The labelling of ram semen in vivo with radioactive phosphate and [carboxy-14C] stearic acid. 1958 Biochem. J. pmid:13522653