stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Cholestasis, Extrahepatic D001651 7 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Infertility D007246 3 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Whooping Cough D014917 6 associated lipids
Urethritis D014526 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Zackler J et al. A mass screening program for the detection of gonorrhea. 1972 Am. J. Obstet. Gynecol. pmid:4623083
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Patil GS et al. Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. 1972 J. Lipid Res. pmid:5075503
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Butcher AE and Jones TM Some physical characteristics of magnesium stearate. 1972 J. Pharm. Pharmacol. pmid:4144914
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Arya OP and Bosa CB In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. 1973 Br J Vener Dis pmid:4748409
McLeay A and Cooke P Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. 1973 Med. J. Aust. pmid:4694278
Norwitz G and Gordon H Determination of lithium stearate in sebacate-based lubricants by atomic absorption. 1973 Talanta pmid:18961363
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. 1973 Yakugaku Zasshi pmid:4797567
Antimicrobial efficacy of erythromycin stearate. A report from the general Practitioner Research Group. 1974 Practitioner pmid:4591200
Caldwell HC Dissolution of lithium and magnesium from lithium carbonate capsules containing magnesium stearate. 1974 J Pharm Sci pmid:4830001
Beleslin DB et al. Hyperthermic effect of palmitate sodium, stearate sodium and oleate sodium injected into the cerebral ventricles of conscious cats. 1974 Neuropharmacology pmid:4840846
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Aveldano MI and Bazán NG Rapid production of diacylglycerols enriched in arachidonate and stearate during early brain ischemia. 1975 J. Neurochem. pmid:1206411
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Morrisett JD et al. Multiple thermotropic phase transitions in Escherichia coli membranes and membrane lipids. A comparison of results obtained by nitroxyl stearate paramagnetic resonance, pyrene excimer fluorescence, and enzyme activity measurements. 1975 J. Biol. Chem. pmid:169264
Asker AF et al. Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions. 1975 Pharmazie pmid:169527
Phadke RS Sedimentation test for procaine benzylpenicillin in oil with aluminium monostearate. III. Substitution of the sedimentation rate for the blood-level duration test of WHO in rabbits. 1975 Aug-Nov Hindustan Antibiot Bull pmid:1236093
Koroly MJ and Conner RL Unsaturated fatty acid biosynthesis in Tetrahymena. Evidence for two pathways. 1976 J. Biol. Chem. pmid:826532
Waring AJ et al. In vivo modification of plant membrane phospholipid composition. 1976 Biochim. Biophys. Acta pmid:953014
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Porra RJ and Stumpf PK Lipid biosynthesis in developing and germinating soybean cotyledons. The formation of palmitate and stearate by chopped tissue and supernatant preparations. 1976 Arch. Biochem. Biophys. pmid:987755
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Yamashita T et al. [Studies on erythromycin stearate capsules (OE-7) (author's transl)]. 1976 Jpn J Antibiot pmid:933342
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Müller WE The use of 8-anilino-1-naphthalenesulfonic acid as a reporter group molecule for circular dichroism and fluorescence measurements. The effect of stearic acid and sodium dodecylsulfate on the conformation of bovine and human serum albumin. 1976 Hoppe-Seyler's Z. Physiol. Chem. pmid:1033907
Norwitz G and Galan M Determination of barium and strontium peroxides (active oxygen) in igniters in small-arms tracer ammunition. 1976 Talanta pmid:18961958
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Ahmed M and Enever RP Influence of magnesium stearate on the dissolution and biological availability of sulphadiazine tablet formulations [proceedings]. 1976 J. Pharm. Pharmacol. pmid:12326
Sabbah A [Letter: Immunodepressive action of erythromycin ethyl-succinate and erythromycin stearate. Study by the lymphoblastic transformation test and natural and rheumatoid rosette test]. 1976 Nouv Presse Med pmid:1264643
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Uyesaka N et al. Lanthanum and some other cation-induced changes in fluidity of synaptosomal membrane studied with nitroxide stearate spin labels. 1976 J. Membr. Biol. pmid:181579
Miller RW and De La Roche IA Properties of spin labelled membranes of Fusarium oxysporum f. sp. lycopersici. 1976 Biochim. Biophys. Acta pmid:182261
Ruf HH and Gratzl M Binding of nitroxide stearate spin labels to bovine serum albumin. 1976 Biochim. Biophys. Acta pmid:184832
Todorow S and Elies W [Oily contrast medium in liquor space following myelography. A clinical-radiological study on extent, velocity and ways of elimination of monoiodine stearate]. 1976 Neurochirurgia (Stuttg) pmid:185538
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Nadkarni MS et al. Treatment of acute bacterial infections of the upper respiratory tract. 1977 Curr Med Res Opin pmid:326492
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Cooksley WG and Powell LW Erythromycin jaundice: diagnosis by an in vitro challenge test. 1977 Aust N Z J Med pmid:269690
Patil GS and Cornwell DG Surface phase separation and collapse of the stearate anion--alkaline earth cation complex. 1977 J. Lipid Res. pmid:833501
Oriel JD et al. Comparison of erythromycin stearate and oxytetracycline in the treatment of non-gonococcal urethritis: their efficacy against Chlamydia trachomatis. 1977 Scott Med J pmid:601555
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