| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Legionnaires' Disease | D007877 | 4 associated lipids |
| Whooping Cough | D014917 | 6 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Simões AP et al. | Incorporation of free fatty acids can explain alterations in the molecular species composition of phosphatidylcholine and phosphatidylethanolamine in human erythrocytes as induced by Plasmodium falciparum. | 1992 | Cell Biol. Int. Rep. | pmid:1327542 |
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| MEAD JF et al. | Metabolism of the essential fatty acids. II. The metabolism of stearate, oleate, and linoleate by fat-deficient and normal mice. | 1956 | J. Biol. Chem. | pmid:13278347 |
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| Fanjul LF et al. | Diacylglycerol rather than Ca2+ mediates GnRH inhibition of FSH induced steroidogenesis in ovarian granulosa cells. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1329745 |
| GLASCOCK RF and REINIUS LR | Studies on the origin of milk fat. 1. The location of tritium in stearic acid produced by the catalytic addition of tritium to elaidic acid. | 1956 | Biochem. J. | pmid:13315207 |
| JAMES AT and MARTIN AJ | Gas-liquid chromatography: the separation and identification of the methyl esters of saturated and unsaturated acids from formic acid to n-octadecanoic acid. | 1956 | Biochem. J. | pmid:13315260 |
| BLOMSTRAND R et al. | On the intestinal absorption of 2, 2-dimethylstearic acid fed as free acid or as glyceride. | 1956 | Acta Physiol. Scand. | pmid:13339456 |
| KERN W et al. | [Suggestions for the composition of the general section on ointments and salve bases and emulsifiers in the German Pharmacopeia (DAB 6, Annex). II]. | 1956 | Hautarzt | pmid:13345190 |
| COOKE NJ et al. | The branched-chain fatty acids of mutton fat. 3. The isolation of 16-methylheptadecanoic acid (isostearic acid). | 1956 | Biochem. J. | pmid:13363830 |
| HUME JC and FACIO G | An analysis of the results of the treatment of yaws with a single injection of procaine penicillin with 2% aluminium monostearate. | 1956 | Bull. World Health Organ. | pmid:13404472 |
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| FABER JS | A note on the assay of zinc stearate. | 1957 | J Am Pharm Assoc Am Pharm Assoc | pmid:13491438 |
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| KUNUGI K | Studies on the syntheses of sucrose fatty acid esters. II. Separation of the alcoholyses products by liquid column chromatography and determination of the contents of sucrose monostearate. | 1963 | Chem. Pharm. Bull. | pmid:13927387 |
| KUNUGI K | Studies on the syntheses of sucrose fatty acid esters. III. Re-esterification of sucrose monostearate. | 1963 | Chem. Pharm. Bull. | pmid:13927388 |
| NAKAGAKI M and NISHINO M | [Studies on the physicochemical properties of aluminum soap. II. Structural viscosity of aluminum stearate in benzene]. | 1963 | Yakugaku Zasshi | pmid:13937343 |
| NIELSEN K and SCHMIDT H | [Should the standard treatment of gonorrhea be changed? Effects of the treatment of gonorrhea in 1960 in ambulant and hospitalized patients]. | 1962 | Manedsskr Prakt Laegegern | pmid:13938514 |
| OSTWALD R | Fat content and fatty acids in some commercial mixes for baked products. | 1963 | J Am Diet Assoc | pmid:13940620 |
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| HALL PF et al. | Synthesis of fatty acids by testicular tissue in vitro. | 1963 | Can J Biochem Physiol | pmid:13952129 |
| HUEPER WC and PAYNE WW | Polyoxyethylene(8)stearate. Carcinogenic studies. | 1963 | Arch. Environ. Health | pmid:13955486 |
| JAMES AT | [Studies on the biosynthesis of 18 carbon mono-and tri-unsaturated fatty acids by gas phase chromatography]. | 1962 | Bull. Soc. Chim. Biol. | pmid:13957228 |
| FOSSA T | [Inhibition of hepatic glucose-6-phosphatase by fatty acids and zinc ions]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13958874 |
| FOTI L et al. | [In vitro liver biosynthesis of cholesterol from acetate, stearate and linoleate 1-C-14]. | 1961 | Boll. Soc. Ital. Biol. Sper. | pmid:13958917 |
| BARGONI N and SISINI A | [Inhibition and reactivation of the hydrolases of digestion]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13966663 |
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| BONE GJ and PARENT G | Stearic acid, an essential growth factor for Trypanosoma cruzi. | 1963 | J. Gen. Microbiol. | pmid:13968755 |
| BONSER GM et al. | A further study of bladder implantation in the mouse as a means of detecting carcinogenic activity: use of crushed paraffin wax or stearic acid as the vehicle. | 1963 | Br. J. Cancer | pmid:13968883 |
| BAKER RW et al. | Fatty-acid composition of brain lecithins in multiple sclerosis. | 1963 | Lancet | pmid:13969172 |
| ROSENBERG MD | Cell guidance by alterations in monomolecular films. | 1963 | Science | pmid:13974905 |
| TROUT DL and ESTES EH | Factors affecting liver uptake of serum free stearic acid-1-C14. | 1962 | Am. J. Physiol. | pmid:13994303 |
| WALLEN LL et al. | The microbiological production of 10-hydroxystearic acid from oleic acid. | 1962 | Arch. Biochem. Biophys. | pmid:13998583 |
| WELD JT et al. | Production of octadecenoic acid in plasma by Staphylococcus aureus. | 1963 | Proc. Soc. Exp. Biol. Med. | pmid:13999824 |
| CREASEY WA | Observations on the activation of stearic acid by rat-liver preparations. | 1962 | Biochim. Biophys. Acta | pmid:14023748 |
| DAVIDOFF F and KORN ED | Synthesis of unsaturated fatty acids in the cellular slime mold. | 1962 | Biochem. Biophys. Res. Commun. | pmid:14025332 |
| DEMPSKI RE et al. | Permeability of excised human keratin to lipid-soluble substances. II. | 1963 | J Pharm Sci | pmid:14026933 |
| DEYKIN D and GOODMAN DS | The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes. | 1962 | J. Biol. Chem. | pmid:14027461 |
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| CORRIN B | ALUMINIUM PNEUMOCONIOSIS. I. IN VITRO COMPARISON OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND A GRANULAR ALUMINIUM POWDER. | 1963 | Br J Ind Med | pmid:14072616 |
| CORRIN B | ALUMINIUM PNEUMOCONIOSIS. II. EFFECT ON THE RAT LUNG OF INTRATRACHEAL INJECTIONS OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND OF A GRANULAR ALUMINIUM POWDER. | 1963 | Br J Ind Med | pmid:14072617 |
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| KUNUGI K | STUDIES ON THE SYNTHESES OF SUCROSE FATTY ACID ESTERS. IV. VELOCITY OF ALCOHOLYSIS REACTION. | 1963 | Chem. Pharm. Bull. | pmid:14075263 |
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| LEAT WM | FATTY ACID COMPOSITION OF THE SERUM LIPIDS OF PIGS GIVEN DIFFERENT AMOUNTS OF LINOLEIC ACID. | 1963 | Biochem. J. | pmid:14097364 |
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| SHORE PA and ALPERS HS | PLATELET DAMAGE INDUCED IN PLASMA BY CERTAIN FATTY ACIDS. | 1963 | Nature | pmid:14098491 |
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| KRITCHEVSKY D | EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS FED CHOLESTEROL-FREE DIETS. | 1964 Jan-Feb | J Atheroscler Res | pmid:14112225 |
| VROMAN L | EFFECTS OF HYDROPHOBIC SURFACES UPON BLOOD COAGULATION. | 1964 | Thromb Diath Haemorrh | pmid:14113384 |
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