| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Legionnaires' Disease | D007877 | 4 associated lipids |
| Whooping Cough | D014917 | 6 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Van Rafelghem MJ and Andersen ME | The effects of perfluorodecanoic acid on hepatic stearoyl-coenzyme A desaturase and mixed function oxidase activities in rats. | 1988 | Fundam Appl Toxicol | pmid:2906022 |
| Baichwal AR and Augsburger LL | Variations in the friction coefficients of tablet lubricants and relationship to their physicochemical properties. | 1988 | J. Pharm. Pharmacol. | pmid:2907013 |
| Huang G et al. | Identification of the thiol ester linked lipids in apolipoprotein B. | 1988 | Biochemistry | pmid:3365394 |
| Periquet B et al. | Fatty acid composition and kinetic behaviour of liver retinyl esters in vitamin A sufficient and deficient rats. | 1988 | Clin. Chim. Acta | pmid:3370842 |
| Brodersen R et al. | Palmitate binding to serum albumin, measured by rate of dialysis. | 1988 | Eur. J. Biochem. | pmid:3371363 |
| Slinger AJ and Isaac RE | Synthesis of apolar ecdysone esters by ovaries of the cockroach Periplaneta americana. | 1988 | Gen. Comp. Endocrinol. | pmid:3371652 |
| Roberts L | Beef and chocolate: a partial reprieve. | 1988 | Science | pmid:3375809 |
| Salo OP et al. | Efficacy and tolerability of erythromycin acistrate and erythromycin stearate in acute skin infections of patients with atopic eczema. | 1988 | J. Antimicrob. Chemother. | pmid:3391871 |
| Rostila T et al. | Erythromycin acistrate and erythromycin stearate in the treatment of non-gonococcal urethritis. | 1988 | J. Antimicrob. Chemother. | pmid:3391873 |
| Männistö PT et al. | Fate of single oral doses of erythromycin acistrate, erythromycin stearate and pelleted erythromycin base analysed by mass-spectrometry in plasma of healthy human volunteers. | 1988 | J. Antimicrob. Chemother. | pmid:3391874 |
| Savolainen S et al. | Tonsillar penetration of erythromycin and its 2'-acetyl ester in patients with chronic tonsillitis. | 1988 | J. Antimicrob. Chemother. | pmid:3391878 |
| Loscalzo J et al. | Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. | 1987 Sep-Oct | Arteriosclerosis | pmid:3675304 |
| Shani J et al. | Efficacy of sustained-release radioprotective drugs in vivo. | 1987 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:2966504 |
| Kringsholm B and Christoffersen P | The nature and the occurrence of birefringent material in different organs in fatal drug addiction. | 1987 May-Jun | Forensic Sci. Int. | pmid:3036675 |
| Udod VM et al. | [Microbial breakdown of stearox-6 and a study of the genetic determination of the nature of the degradative activity]. | 1987 May-Jun | Mikrobiol. Zh. | pmid:3150493 |
| Fatemi SH et al. | The glycophospholipid anchor of Thy-1. Biosynthetic labeling experiments with wild-type and class E Thy-1 negative lymphomas. | 1987 | J. Biol. Chem. | pmid:2881925 |
| Nakanishi H et al. | Comparative studies on additive effects of sodium dodecylbenzensulfonate and sodium stearate on uptake of chemicals by willow shiner (Gnathopogon caerulescens). | 1987 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:2882933 |
| Bergquist SO et al. | Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. | 1987 | Pediatr. Infect. Dis. J. | pmid:2885802 |
| Zara GP et al. | Erythromycin and gastrointestinal motility. | 1987 | Lancet | pmid:2889954 |
| DeGeorge JJ et al. | Acetylcholine stimulates selective liberation and re-esterification of arachidonate and accumulation of inositol phosphates and glycerophosphoinositol in C62B glioma cells. | 1987 | J. Biol. Chem. | pmid:3110145 |
| Morse DR et al. | Infectious flare-ups and serious sequelae following endodontic treatment: a prospective randomized trial on efficacy of antibiotic prophylaxis in cases of asymptomatic pulpal-periapical lesions. | 1987 | Oral Surg. Oral Med. Oral Pathol. | pmid:3112672 |
| Crost S et al. | Hormonal effects on mitochondrial respiration: potential role of endogenous lipolytic activities. | 1987 | Arch. Biochem. Biophys. | pmid:3113334 |
| Halát G et al. | Effects of incomplete ischemia and subsequent recirculation on free palmitate, stearate, oleate and arachidonate levels in lumbar and cervical spinal cord of rabbit. | 1987 | Gen. Physiol. Biophys. | pmid:3117617 |
| Hohl C and Rösen P | Arachidonic acid metabolism in isolated rat heart myocytes. | 1987 | Prog. Clin. Biol. Res. | pmid:3118380 |
| Taylor AJ et al. | An alternative explanation for the changes in erythrocyte fatty acids observed in diabetes mellitus. | 1987 | Clin. Chem. | pmid:3119255 |
| Shanson DC | Antibiotic prophylaxis of infective endocarditis in the United Kingdom and Europe. | 1987 | J. Antimicrob. Chemother. | pmid:3119557 |
| Dudley DT et al. | Depletion of arachidonic acid from GH3 cells. Effects on inositol phospholipid turnover and cellular activation. | 1987 | Biochem. J. | pmid:3120699 |
| Faden AI et al. | Alterations in lipid metabolism, Na+,K+-ATPase activity, and tissue water content of spinal cord following experimental traumatic injury. | 1987 | J. Neurochem. | pmid:3033150 |
| Imai A and Gershengorn MC | Measurement of lipid turnover in response to thyrotropin-releasing hormone. | 1987 | Meth. Enzymol. | pmid:3037241 |
| Feix JB et al. | Interactions of 14N:15N stearic acid spin-label pairs: effects of host lipid alkyl chain length and unsaturation. | 1987 | Biochemistry | pmid:2820479 |
| Roughan PG et al. | Metabolism of exogenous long-chain fatty acids by spinach leaves. | 1987 | Arch. Biochem. Biophys. | pmid:3426240 |
| Tonnet ML and Green AG | Characterization of the seed and leaf lipids of high and low linolenic acid flax genotypes. | 1987 | Arch. Biochem. Biophys. | pmid:3813554 |
| Ong DE et al. | Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine. | 1987 | J. Biol. Chem. | pmid:3818619 |
| Albertini G et al. | Studies of structural modifications induced by gamma-irradiation in distearoylphosphatidylcholine liposomes. | 1987 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:3496306 |
| Carter BL et al. | Gastrointestinal side effects with erythromycin preparations. | 1987 | Drug Intell Clin Pharm | pmid:3498618 |
| Seifert R et al. | Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3426598 |
| Bos CE et al. | Native starch in tablet formulations: properties on compaction. | 1987 | Pharm Weekbl Sci | pmid:3432037 |
| Bridges CD et al. | Rhodopsin, vitamin A, and interstitial retinol-binding protein in the rd chicken. | 1987 | Invest. Ophthalmol. Vis. Sci. | pmid:3557867 |
| Hope MJ and Cullis PR | Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. | 1987 | J. Biol. Chem. | pmid:3558410 |
| Husebye ES and Flatmark T | Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. | 1987 | Biochim. Biophys. Acta | pmid:3607074 |
| Cavalleri A and Minoia C | Lead level of whole blood and plasma in workers exposed to lead stearate. | 1987 | Scand J Work Environ Health | pmid:3616550 |
| Seimiya T et al. | Effects of composition and molecular packing on ionic properties of lipid monolayer having both cationic and anionic head groups. | 1987 | Chem. Phys. Lipids | pmid:3621383 |
| Salminen S and Salminen E | Urinary excretion of orally administered oxalic acid in MYRJ 45-treated NMRI mice. | 1987 | Toxicol. Lett. | pmid:3590233 |
| Masuzawa Y et al. | Distribution of dietary trans-octadecenoate among acyl-CoA and other lipid fractions of rat liver and heart. | 1987 | Biochim. Biophys. Acta | pmid:3593750 |
| Kolesnick RN and Paley AE | 1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action. | 1987 | J. Biol. Chem. | pmid:3597411 |
| Habib NA et al. | Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas. | 1987 | Int J Colorectal Dis | pmid:3598325 |
| Pyörälä S | Effect of some vehicles used in intramammary mastitis preparations on inflammation indicators in milk. | 1987 | J. Vet. Pharmacol. Ther. | pmid:3656512 |
| Emken EA et al. | Metabolism in humans of cis-12,trans-15-octadecadienoic acid relative to palmitic, stearic, oleic and linoleic acids. | 1987 | Lipids | pmid:3306237 |
| Dinman BD | Aluminum in the lung: the pyropowder conundrum. | 1987 | J Occup Med | pmid:3316541 |
| McCormack WM et al. | Effect on birth weight of erythromycin treatment of pregnant women. | 1987 | Obstet Gynecol | pmid:3543767 |