| MeSH term | MeSH ID | Detail |
|---|---|---|
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Legionnaires' Disease | D007877 | 4 associated lipids |
| Whooping Cough | D014917 | 6 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| van den Reek MM et al. | Use of published analyses of food items to determine dietary trans octadecenoic acid. | 1986 | J Am Diet Assoc | pmid:3760430 |
| Ball MD et al. | Acyl coenzyme A:retinol acyltransferase activity and the vitamin A content of polar bear (Ursus maritimus) liver. | 1986 | Comp. Biochem. Physiol., B | pmid:3757481 |
| Muralidharan FN and Muralidharan VB | Phytanoyl-CoA ligase activity in rat liver. | 1986 | Biochem. Int. | pmid:3753503 |
| Dunlop EM et al. | Penicillin levels in blood and CSF achieved by treatment of syphilis. | 1979 | JAMA | pmid:374763 |
| Ito Y et al. | Fatty acid synthetase as a thermoreceptor in Candida utilis. | 1986 | J. Biochem. | pmid:3745143 |
| Alcalay J et al. | Asymptomatic liver injury due to erythromycin stearate. | 1986 Jul-Aug | Drug Intell Clin Pharm | pmid:3743417 |
| Chester DW et al. | The influence of saturated fatty acid modulation of bilayer physical state on cellular and membrane structure and function. | 1986 | Biochim. Biophys. Acta | pmid:3741857 |
| Fujii T et al. | Effect of exogenous lipids incorporated into the membrane of human erythrocytes on its glucose transport activity. | 1986 | Biochem. Int. | pmid:3741447 |
| Chowhan ZT and Chi LH | Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution. | 1986 | J Pharm Sci | pmid:3735097 |
| Chowhan ZT and Chi LH | Drug-excipient interactions resulting from powder mixing. III: Solid state properties and their effect on drug dissolution. | 1986 | J Pharm Sci | pmid:3735096 |
| Carter-Dawson L et al. | Rhodopsin, 11-cis vitamin A, and interstitial retinol-binding protein (IRBP) during retinal development in normal and rd mutant mice. | 1986 | Dev. Biol. | pmid:3732615 |
| Oh-Hashi Y et al. | Temperature- and growth-phase-dependent changes in membrane fatty acid compositions of Brevibacterium ammoniagenes. | 1986 | Arch. Biochem. Biophys. | pmid:3729431 |
| Wan LS and Choong YL | The effect of excipients on the penetration of liquid into tablets. | 1986 | Pharm Acta Helv | pmid:3725815 |
| Chalupa W et al. | Ruminal fermentation in vivo as influenced by long-chain fatty acids. | 1986 | J. Dairy Sci. | pmid:3722545 |
| Beaumelle BD and Vial HJ | Modification of the fatty acid composition of individual phospholipids and neutral lipids after infection of the simian erythrocyte by Plasmodium knowlesi. | 1986 | Biochim. Biophys. Acta | pmid:3719005 |
| Caponnetto A et al. | [Correlations between unsaturated fatty acids and medium C-chain triglycerides]. | 1986 | Boll. Soc. Ital. Biol. Sper. | pmid:3718739 |
| Heape AM et al. | Technique for injection into the sciatic nerve of the mouse for quantitative in vivo metabolic studies. | 1986 | Anal. Biochem. | pmid:3717558 |
| Thompson W and Belina H | Rapid accumulation of diacyl lipid in rat liver microsomes by selective acylation of 2-acyl-sn-glycero-3-phosphorylserine. | 1986 | Biochim. Biophys. Acta | pmid:3707975 |
| Okabe H et al. | Effects of anti-convulsants on fatty acid metabolism in human serum. | 1986 | Tohoku J. Exp. Med. | pmid:3705068 |
| Shah KB et al. | An investigation of some factors influencing plug formation and fill weight in a dosing disk-type automatic capsule-filling machine. | 1986 | J Pharm Sci | pmid:3701614 |
| Goto S et al. | [Role of metal stearates in preparation of Eudragit RS-microcapsules containing sulfamethizole by evaporation process in water phase]. | 1986 | Yakugaku Zasshi | pmid:3701600 |
| Kaya K and Nohara K | Effect of di-n-octyl phthalate on fatty acid composition of phosphatidylcholine in Tetrahymena. | 1987 | Chem. Biol. Interact. | pmid:3690725 |
| Habib NA et al. | Stearic acid and carcinogenesis. | 1987 | Br. J. Cancer | pmid:3689663 |
| Venho VM et al. | The value of comparative bioavailability studies of marketed drugs in drug control. An example with erythromycin stearate. | 1987 | Methods Find Exp Clin Pharmacol | pmid:3683018 |
| Loscalzo J et al. | Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. | 1987 Sep-Oct | Arteriosclerosis | pmid:3675304 |
| Caglayan S et al. | Is medical therapy effective for regional lymphadenitis following BCG vaccination? | 1987 | Am. J. Dis. Child. | pmid:3673975 |
| Mäntylä R et al. | Bioavailability and effect of food on the gastrointestinal absorption of two erythromycin derivatives. | 1978 | Ann. Clin. Res. | pmid:367255 |
| Worman CP et al. | Saturation index of blood cell membrane fatty acids before and after IFN treatment in hairy cell leukemia. | 1987 | Leukemia | pmid:3669764 |
| Pyörälä S | Effect of some vehicles used in intramammary mastitis preparations on inflammation indicators in milk. | 1987 | J. Vet. Pharmacol. Ther. | pmid:3656512 |
| Seimiya T et al. | Effects of composition and molecular packing on ionic properties of lipid monolayer having both cationic and anionic head groups. | 1987 | Chem. Phys. Lipids | pmid:3621383 |
| Cavalleri A and Minoia C | Lead level of whole blood and plasma in workers exposed to lead stearate. | 1987 | Scand J Work Environ Health | pmid:3616550 |
| Husebye ES and Flatmark T | Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. | 1987 | Biochim. Biophys. Acta | pmid:3607074 |
| Habib NA et al. | Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas. | 1987 | Int J Colorectal Dis | pmid:3598325 |
| Kolesnick RN and Paley AE | 1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action. | 1987 | J. Biol. Chem. | pmid:3597411 |
| Masuzawa Y et al. | Distribution of dietary trans-octadecenoate among acyl-CoA and other lipid fractions of rat liver and heart. | 1987 | Biochim. Biophys. Acta | pmid:3593750 |
| Salminen S and Salminen E | Urinary excretion of orally administered oxalic acid in MYRJ 45-treated NMRI mice. | 1987 | Toxicol. Lett. | pmid:3590233 |
| PospÃsilová B and Kubes J | [Stability of erythromycin stearate in coated tablets during the action of gastric juice in vitro]. | 1987 | Cesk Farm | pmid:3581192 |
| Wang ST et al. | A comparison of fatty acid composition of cholesteryl esters in subjects at various concentrations of serum lipid. | 1987 | Clin. Biochem. | pmid:3568345 |
| Habib NA et al. | Desaturation-producing factor present in the tissue, blood, and urine of cancer patients. | 1987 | Cancer Detect. Prev. | pmid:3568009 |
| Hope MJ and Cullis PR | Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. | 1987 | J. Biol. Chem. | pmid:3558410 |
| Bridges CD et al. | Rhodopsin, vitamin A, and interstitial retinol-binding protein in the rd chicken. | 1987 | Invest. Ophthalmol. Vis. Sci. | pmid:3557867 |
| McCormack WM et al. | Effect on birth weight of erythromycin treatment of pregnant women. | 1987 | Obstet Gynecol | pmid:3543767 |
| Muñoz-Espin T et al. | Erythromycin versus tetracycline for treatment of Mediterranean spotted fever. | 1986 | Arch. Dis. Child. | pmid:3535687 |
| Slomiany BL et al. | Mucus glycoprotein of human saliva: differences in the associated and covalently bound lipids with caries. | 1986 | Biochim. Biophys. Acta | pmid:3518803 |
| Goto S et al. | Eudragit E, L and S (acrylic resins) microcapsules as pH sensitive release preparations of ketoprofen. | 1986 Oct-Dec | J Microencapsul | pmid:3508191 |
| Goto S et al. | Eudragit RS and RL (acrylic resins) microcapsules as pH insensitive and sustained release preparations of ketoprofen. | 1986 Oct-Dec | J Microencapsul | pmid:3508190 |
| Carter BL et al. | Gastrointestinal side effects with erythromycin preparations. | 1987 | Drug Intell Clin Pharm | pmid:3498618 |
| Albertini G et al. | Studies of structural modifications induced by gamma-irradiation in distearoylphosphatidylcholine liposomes. | 1987 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:3496306 |
| Ras GJ and Anderson R | An in-vitro study of oral therapeutic doses of co-trimoxazole and erythromycin stearate on abnormal polymorphonuclear leucocyte migration. | 1986 | J. Antimicrob. Chemother. | pmid:3486178 |
| Pajor L et al. | Microsomal desaturation of stearic acid in relation to lymphocyte activation. | 1986 | Arch. Biochem. Biophys. | pmid:3485399 |
| Matsui MS and Jeffrey AM | Fatty acid modification of C3H 10T 1/2 fibroblast cells: changes in benzo(a)pyrene metabolism and phorbol ester binding. | 1987 | Cancer Res. | pmid:3471326 |
| Peura P et al. | The effect of ethanol on the release of free fatty acids from the brain in vivo; a study with push-pull cannula. | 1986 | Arch. Toxicol. Suppl. | pmid:3468932 |
| Cutler RR et al. | The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. | 1987 | Tubercle | pmid:3448797 |
| Hasin Y et al. | Dietary lipid intake and myocardial electrophysiology. | 1987 | Isr. J. Med. Sci. | pmid:3440741 |
| Nadai M et al. | [Correlation between in vitro dissolution characteristics of macrolide antibiotic tablets and bioavailability in man]. | 1987 | Yakugaku Zasshi | pmid:3437396 |
| Bos CE et al. | Native starch in tablet formulations: properties on compaction. | 1987 | Pharm Weekbl Sci | pmid:3432037 |
| Rhoads DE et al. | Metabolism of saturated fatty acids by Paramecium tetraurelia. | 1987 | J. Lipid Res. | pmid:3430068 |
| Seifert R et al. | Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3426598 |
| Roughan PG et al. | Metabolism of exogenous long-chain fatty acids by spinach leaves. | 1987 | Arch. Biochem. Biophys. | pmid:3426240 |
| Trinchera M et al. | Different metabolic recycling of the lipid components of exogenous sulphatide in human fibroblasts. | 1988 | Biochem. J. | pmid:3415659 |
| Rahman MD et al. | Effects of sulfur-containing analogues of stearic acid on growth and fatty acid biosynthesis in the protozoan Crithidia fasciculata. | 1988 | J. Med. Chem. | pmid:3398003 |
| Pitt WG and Cooper SL | Albumin adsorption on alkyl chain derivatized polyurethanes: I. The effect of C-18 alkylation. | 1988 | J. Biomed. Mater. Res. | pmid:3397377 |
| Ogata S et al. | Chemical characterization of the membrane-anchoring domain of human placental alkaline phosphatase. | 1988 | J. Biol. Chem. | pmid:3392021 |
| Viluksela M et al. | Comparative liver toxicity of various erythromycin derivatives in animals. | 1988 | J. Antimicrob. Chemother. | pmid:3391880 |
| Savolainen S et al. | Tonsillar penetration of erythromycin and its 2'-acetyl ester in patients with chronic tonsillitis. | 1988 | J. Antimicrob. Chemother. | pmid:3391878 |
| Männistö PT et al. | Fate of single oral doses of erythromycin acistrate, erythromycin stearate and pelleted erythromycin base analysed by mass-spectrometry in plasma of healthy human volunteers. | 1988 | J. Antimicrob. Chemother. | pmid:3391874 |
| Rostila T et al. | Erythromycin acistrate and erythromycin stearate in the treatment of non-gonococcal urethritis. | 1988 | J. Antimicrob. Chemother. | pmid:3391873 |
| Salo OP et al. | Efficacy and tolerability of erythromycin acistrate and erythromycin stearate in acute skin infections of patients with atopic eczema. | 1988 | J. Antimicrob. Chemother. | pmid:3391871 |
| Roberts L | Beef and chocolate: a partial reprieve. | 1988 | Science | pmid:3375809 |
| Slinger AJ and Isaac RE | Synthesis of apolar ecdysone esters by ovaries of the cockroach Periplaneta americana. | 1988 | Gen. Comp. Endocrinol. | pmid:3371652 |
| Brodersen R et al. | Palmitate binding to serum albumin, measured by rate of dialysis. | 1988 | Eur. J. Biochem. | pmid:3371363 |
| Periquet B et al. | Fatty acid composition and kinetic behaviour of liver retinyl esters in vitamin A sufficient and deficient rats. | 1988 | Clin. Chim. Acta | pmid:3370842 |
| Huang G et al. | Identification of the thiol ester linked lipids in apolipoprotein B. | 1988 | Biochemistry | pmid:3365394 |
| Rosenberg IH and Schaefer EJ | Dietary saturated fatty acids and blood cholesterol. | 1988 | N. Engl. J. Med. | pmid:3362180 |
| Bonanome A and Grundy SM | Effect of dietary stearic acid on plasma cholesterol and lipoprotein levels. | 1988 | N. Engl. J. Med. | pmid:3362176 |
| Graham A et al. | Fatty acid specificity for the synthesis of triacylglycerol and phosphatidylcholine and for the secretion of very-low-density lipoproteins and lysophosphatidylcholine by cultures of rat hepatocytes. | 1988 | Biochem. J. | pmid:3355493 |
| Sanjurjo P et al. | Plasma fatty acid composition during the first week of life following feeding with human milk or formula. | 1988 | Acta Paediatr Scand | pmid:3354331 |
| Bull AW et al. | Structural requirements for stimulation of colonic cell proliferation by oxidized fatty acids. | 1988 | Cancer Res. | pmid:3349456 |
| Dinman BD | Aluminum in the lung: the pyropowder conundrum. | 1987 | J Occup Med | pmid:3316541 |
| Emken EA et al. | Metabolism in humans of cis-12,trans-15-octadecadienoic acid relative to palmitic, stearic, oleic and linoleic acids. | 1987 | Lipids | pmid:3306237 |
| Longmuir KJ and Rossi ME | Fatty acid chain-shortening activity in the pulmonary type II cell. | 1988 | Biochim. Biophys. Acta | pmid:3289622 |
| Nakayoshi T et al. | Comparative study on effects of 14- and 16-membered macrolides on gastrointestinal motility in unanaesthetized dogs. | 1988 | Drugs Exp Clin Res | pmid:3265375 |
| Nadkarni MS et al. | Treatment of acute bacterial infections of the upper respiratory tract. | 1977 | Curr Med Res Opin | pmid:326492 |
| Simpson JT et al. | Identification of major lipids from the scent gland secretions of Dumeril's ground boa (Acrantophis dumerili Jan) by gas chromatography-mass spectrometry. | 1988 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:3245880 |
| Stewart AG et al. | The release of a model low-dose drug (riboflavine) from hard gelatin capsule formulations. | 1979 | J. Pharm. Pharmacol. | pmid:32357 |
| Ubels JL et al. | Vitamin A is stored as fatty acyl esters of retinol in the lacrimal gland. | 1988 | Curr. Eye Res. | pmid:3229120 |
| Meakin BJ et al. | The implication of stearate mould release agents in the loss of benzalkonium chloride from ophthalmic solutions in polyethylene bottles [proceedings]. | 1978 | J. Pharm. Pharmacol. | pmid:32268 |
| Broderick PA | Distinguishing in vitro electrochemical signatures for norepinephrine and dopamine. | 1988 | Neurosci. Lett. | pmid:3226613 |
| Yeh YY | Long chain fatty acid deficits in brain myelin sphingolipids of undernourished rat pups. | 1988 | Lipids | pmid:3226227 |
| Tan S et al. | Gas chromatographic determination of calcium stearate in polyethylene food packaging sheets. | 1988 | J. Chromatogr. | pmid:3209663 |
| McNulty CA et al. | Inhibitory antimicrobial concentrations against Campylobacter pylori in gastric mucosa. | 1988 | J. Antimicrob. Chemother. | pmid:3209531 |
| Zanetti R and Catalá A | Lipid binding properties of fatty acid binding protein isolated from mouse liver. | 1988 | Acta Physiol Pharmacol Latinoam | pmid:3201993 |
| Heyman SN et al. | Erythromycin-induced dynamic ileus? | 1988 | J. Clin. Gastroenterol. | pmid:3183328 |
| Korkeala H and Männistö PT | Time course of the antibacterial activity of erythromycin stearate and erythromycin acistrate against two Staphylococcus aureus strains in vitro. | 1988 | J. Antimicrob. Chemother. | pmid:3182415 |
| Morasso MI et al. | Effect of mixing on the biopharmaceutical properties of sulfadiazine tablets. | 1988 | Farmaco Prat | pmid:3181415 |
| Ricevuti G et al. | Serum, sputum and bronchial concentrations of erythromycin in chronic bronchitis after single and multiple treatments with either propionate-N-acetylcysteinate or stearate erythromycin. | 1988 | Chemotherapy | pmid:3180905 |
| de Groot AC et al. | Cosmetic allergy from stearic acid and glyceryl stearate. | 1988 | Contact Derm. | pmid:3180776 |
| Effect of dietary stearic acid on plasma cholesterol level. | 1988 | N. Engl. J. Med. | pmid:3173438 | |
| Ertel KD and Carstensen JT | Chemical, physical, and lubricant properties of magnesium stearate. | 1988 | J Pharm Sci | pmid:3171951 |
| Bach R et al. | Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine. | 1988 | Biochemistry | pmid:3166978 |