| MeSH term | MeSH ID | Detail |
|---|---|---|
| Eczema, Dyshidrotic | D011146 | 1 associated lipids |
| Decalcification, Pathologic | D003649 | 1 associated lipids |
| Salivary Duct Calculi | D012465 | 2 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Calculi | D002137 | 3 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Anderson EK et al. | Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. | 2012 | Arterioscler. Thromb. Vasc. Biol. | pmid:22556332 |
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| Kwon Y et al. | Arabidopsis serine decarboxylase mutants implicate the roles of ethanolamine in plant growth and development. | 2012 | Int J Mol Sci | pmid:22489147 |
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| Milicic A et al. | Small cationic DDA:TDB liposomes as protein vaccine adjuvants obviate the need for TLR agonists in inducing cellular and humoral responses. | 2012 | PLoS ONE | pmid:22470545 |
| Mason P et al. | SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids. | 2012 | PLoS ONE | pmid:22457791 |
| Olivieri C et al. | Phylogenetic position of a copper age sheep (Ovis aries) mitochondrial DNA. | 2012 | PLoS ONE | pmid:22457789 |
| Scalia S et al. | Preparation and in vitro evaluation of salbutamol-loaded lipid microparticles for sustained release pulmonary therapy. | 2012 | J Microencapsul | pmid:22208706 |
| Duong CT and Roper MG | A microfluidic device for the automated derivatization of free fatty acids to fatty acid methyl esters. | 2012 | Analyst | pmid:22166918 |
| Zhen Z and Xie J | Development of manganese-based nanoparticles as contrast probes for magnetic resonance imaging. | 2012 | Theranostics | pmid:22272218 |
| Imae R et al. | LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice. | 2012 | J. Lipid Res. | pmid:22172515 |
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| Casiraghi A et al. | The influence of the polar head and the hydrophobic chain on the skin penetration enhancement effect of poly(ethylene glycol) derivatives. | 2012 | AAPS PharmSciTech | pmid:22232021 |
| Wei CC and Ge ZQ | Influence of electrolyte and poloxamer 188 on the aggregation kinetics of solid lipid nanoparticles (SLNs). | 2012 | Drug Dev Ind Pharm | pmid:22181005 |
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| Chapple IL et al. | Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double-blind RCT. | 2012 | J. Clin. Periodontol. | pmid:22093005 |
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| Ruiz M et al. | A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. | 2012 | PLoS ONE | pmid:23056435 |
| Mekhail GM et al. | Anticancer effect of atorvastatin nanostructured polymeric micelles based on stearyl-grafted chitosan. | 2012 | Int. J. Biol. Macromol. | pmid:22652220 |
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| Choi du H et al. | A new experimental design method to optimize formulations focusing on a lubricant for hydrophilic matrix tablets. | 2012 | Drug Dev Ind Pharm | pmid:22348254 |
| Kim DH et al. | Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function. | 2012 | Colloids Surf B Biointerfaces | pmid:22361356 |
| Honkanen AM et al. | Characterization of the disappearance and formation of biohydrogenation intermediates during incubations of linoleic acid with rumen fluid in vitro. | 2012 | J. Dairy Sci. | pmid:22365221 |
| Kushner J | Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume. | 2012 | Int J Pharm | pmid:22405966 |
| Matsui H et al. | Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes. | 2012 | PLoS ONE | pmid:22413010 |
| Trupp M et al. | Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. | 2012 | PLoS ONE | pmid:22808006 |
| Schreiber R et al. | Retinyl ester hydrolases and their roles in vitamin A homeostasis. | 2012 | Biochim. Biophys. Acta | pmid:21586336 |
| Bonaduce I et al. | New insights into the ageing of linseed oil paint binder: a qualitative and quantitative analytical study. | 2012 | PLoS ONE | pmid:23166642 |
| Kurotani K et al. | High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. | 2012 | Nutr Res | pmid:23084639 |
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| Nesarikar VV et al. | Instrumented roll technology for the design space development of roller compaction process. | 2012 | Int J Pharm | pmid:22286023 |
| Toubiana D et al. | Metabolic profiling of a mapping population exposes new insights in the regulation of seed metabolism and seed, fruit, and plant relations. | 2012 | PLoS Genet. | pmid:22479206 |
| Eili M et al. | Degradability enhancement of poly(lactic acid) by stearate-Zn(3)Al LDH nanolayers. | 2012 | Int J Mol Sci | pmid:22942682 |
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| Schrank S et al. | Ibuprofen-loaded calcium stearate pellets: drying-induced variations in dosage form properties. | 2012 | AAPS PharmSciTech | pmid:22552931 |
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