stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Eczema, Dyshidrotic D011146 1 associated lipids
Decalcification, Pathologic D003649 1 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Infertility D007246 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Dubrovin EV et al. Statistical analysis of molecular nanotemplate driven DNA adsorption on graphite. 2014 Langmuir pmid:25470069
Wu JX et al. Chemical imaging and solid state analysis at compact surfaces using UV imaging. 2014 Int J Pharm pmid:25445531
Treffer D et al. In-line implementation of an image-based particle size measurement tool to monitor hot-melt extruded pellets. 2014 Int J Pharm pmid:24614578
Haware RV et al. Application of multivariate methods to evaluate the functionality of bovine- and vegetable-derived magnesium stearate. 2014 J Pharm Sci pmid:24596131
Guo H et al. In vitro and in vivo study of Gal-OS self-assembled nanoparticles for liver-targeting delivery of doxorubicin. 2014 J Pharm Sci pmid:24549734
Nehdi IA et al. Chamaerops humilis L. var. argentea André date palm seed oil: a potential dietetic plant product. 2014 J. Food Sci. pmid:24666023
Lorenzo JM Changes on physico-chemical, textural, lipolysis and volatile compounds during the manufacture of dry-cured foal "cecina". 2014 Meat Sci. pmid:23916960
Park H et al. Stacking of a stearoyl-ACP thioesterase with a dual-silenced palmitoyl-ACP thioesterase and ∆12 fatty acid desaturase in transgenic soybean. 2014 Plant Biotechnol. J. pmid:24909647
Gillman JD et al. Deletions of the SACPD-C locus elevate seed stearic acid levels but also result in fatty acid and morphological alterations in nitrogen fixing nodules. 2014 BMC Plant Biol. pmid:24886084
Carrero-Colón M et al. Mutations in SACPD-C result in a range of elevated stearic acid concentration in soybean seed. 2014 PLoS ONE pmid:24846334
Gebauer SK et al. Impact of stearic acid and oleic acid on hemostatic factors in the context of controlled diets consumed by healthy men. 2014 Eur J Clin Nutr pmid:24736679
Wang JL et al. Preparation and characterization of novel lipid carriers containing microalgae oil for food applications. 2014 J. Food Sci. pmid:24446860
Gao L et al. Cloning and functional expression of a cDNA encoding stearoyl-ACP Δ9-desaturase from the endosperm of coconut (Cocos nucifera L.). 2014 Gene pmid:25038276
Arijaje EO et al. Effects of chemical and enzymatic modifications on starch-stearic acid complex formation. 2014 J. Agric. Food Chem. pmid:24641427
Zhao X et al. Diet modulation is an effective complementary agent in preventing and treating breast cancer lung metastasis. 2014 Clin. Exp. Metastasis pmid:24832758
Aznar-Moreno JA et al. Sunflower (Helianthus annuus) long-chain acyl-coenzyme A synthetases expressed at high levels in developing seeds. 2014 Physiol Plant pmid:24102504
Huang FC et al. Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. 2014 Appl. Environ. Microbiol. pmid:24242247
Sassa T et al. Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid. 2014 J. Lipid Res. pmid:24489110
Liu J et al. Saturated fatty acids up-regulate COX-2 expression in prostate epithelial cells via toll-like receptor 4/NF-κB signaling. 2014 Inflammation pmid:24221358
Kushner J et al. A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes. 2014 J Pharm Sci pmid:24375069