stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Relapsing Fever D012061 3 associated lipids
Infertility D007246 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Wall L et al. A phase I and pharmacological study of the matrix metalloproteinase inhibitor BB-3644 in patients with solid tumours. 2004 Br. J. Cancer pmid:14970856
Lalman JA et al. Kinetics of glucose fermentation by a mixed culture in the presence of linoleic, oleic, and stearic acid. 2003 Environ Technol pmid:14977143
Sungthongjeen S et al. Development of pulsatile release tablets with swelling and rupturable layers. 2004 J Control Release pmid:14980764
Iida K et al. Effect of surface layering time of lactose carrier particles on dry powder inhalation properties of salbutamol sulfate. 2004 Chem. Pharm. Bull. pmid:14993760
Mani N et al. Microencapsulation of a hydrophilic drug into a hydrophobic matrix using a salting-out procedure. II. Effects of adsorbents on microsphere properties. 2004 Drug Dev Ind Pharm pmid:15000433
Abdoh A et al. Amlodipine besylate-excipients interaction in solid dosage form. 2004 Pharm Dev Technol pmid:15000463
Kumar M K et al. Effect of drug solubility and different excipients on floating behaviour and release from glyceryl monooleate matrices. 2004 Int J Pharm pmid:15019078
Roberts M et al. Effect of lubricant type and concentration on the punch tip adherence of model ibuprofen formulations. 2004 J. Pharm. Pharmacol. pmid:15025854
Sauer LA and Dauchy RT Uptake of plasma lipids by tissue-isolated hepatomas 7288CTC and 7777 in vivo. 1992 Br. J. Cancer pmid:1503901
Bai YJ et al. [Structure identification of jujuboside E]. 2003 Yao Xue Xue Bao pmid:15040089
Wilson RA et al. Two Delta9-stearic acid desaturases are required for Aspergillus nidulans growth and development. 2004 Fungal Genet. Biol. pmid:15050539
Judd AM and MacLeod RM Thyrotropin-releasing hormone and lysine-bradykinin stimulate arachidonate liberation from rat anterior pituitary cells through different mechanisms. 1992 Endocrinology pmid:1505463
Iida K et al. Influence of storage humidity on the in vitro inhalation properties of salbutamol sulfate dry powder with surface covered lactose carrier. 2004 Chem. Pharm. Bull. pmid:15056961
Furusawa H and Koyama N Effect of fatty acids on the membrane potential of an alkaliphilic bacillus. 2004 Curr. Microbiol. pmid:15057464
Pohl J et al. Long-chain fatty acid uptake into adipocytes depends on lipid raft function. 2004 Biochemistry pmid:15065861
Miyazaki M et al. Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. 2004 J. Biol. Chem. pmid:15066988
Sixsmith D The properties of tablets containing microcrystalline cellulose. 1977 J. Pharm. Pharmacol. pmid:15069
Romero-Bastida CA et al. Compositional and moisture content effects on the biodegradability of zein/ethylcellulose films. 2004 J. Agric. Food Chem. pmid:15080626
Johnson PE et al. Effects of stearic acid and beef tallow on iron utilization by the rat. 1992 Proc. Soc. Exp. Biol. Med. pmid:1508937
Gomez GA et al. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. 2004 Biochemistry pmid:15096040
Zhao H and Hardy RW Long-chain saturated fatty acids induce annexin II translocation to detergent-resistant membranes. 2004 Biochem. J. pmid:15099193
Breuer S et al. Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions. 2004 BMC Neurosci pmid:15099403
Wheelan P and Clay KL Albumin and fatty acid effects on the stimulated production of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) by human polymorphonuclear leukocytes. 1992 Biochim. Biophys. Acta pmid:1511005
Olbrich C et al. Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene-cytotoxicity testing and mouse serum adsorption. 2004 J Control Release pmid:15120899
Katoh K et al. Saturated fatty acids suppress adrenocorticotropic hormone (ACTH) release from rat anterior pituitary cells in vitro. 2004 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:15123208
Flynn TT et al. Modification of plasma and hepatic lipids of guinea pigs by feeding high oleic acid pork compared with regular pork. 1992 J. Nutr. pmid:1512635
Willie BM et al. Quantifying the effect of resin type and sterilization method on the degradation of ultrahigh molecular weight polyethylene after 4 years of real-time shelf aging. 2004 J Biomed Mater Res A pmid:15127395
Bojar RA et al. The effect of lipids on the adherence of axillary aerobic coryneform bacteria. 2004 Lett. Appl. Microbiol. pmid:15130141
Wieland SJ et al. Differential modulation of a sodium conductance in skeletal muscle by intracellular and extracellular fatty acids. 1992 Am. J. Physiol. pmid:1514578
Santos WL et al. Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid. 2004 Bioorg. Med. Chem. Lett. pmid:15177455
Dohme F et al. Digestive and metabolic utilization of lauric, myristic and stearic acid in cows, and associated effects on milk fat quality. 2004 Arch Anim Nutr pmid:15195905
Abdelbary G et al. The preparation of orally disintegrating tablets using a hydrophilic waxy binder. 2004 Int J Pharm pmid:15196646
Horoz BB et al. Effect of different dispersing agents on the characteristics of Eudragit microspheres prepared by a solvent evaporation method. 2004 J Microencapsul pmid:15198430
Räsänen E et al. A new method to predict flowability using a microscale fluid bed. 2003 AAPS PharmSciTech pmid:15198548
Vueba ML et al. Influence of cellulose ether polymers on ketoprofen release from hydrophilic matrix tablets. 2004 Eur J Pharm Biopharm pmid:15207537
Romão RI and Gonçalves da Silva AM Phase behaviour and morphology of binary mixtures of DPPC with stearonitrile, stearic acid, and octadecanol at the air-water interface. 2004 Chem. Phys. Lipids pmid:15210362
Giuffrida F et al. Structural analysis of hydroperoxy- and epoxy-triacylglycerols by liquid chromatography mass spectrometry. 2004 Chem. Phys. Lipids pmid:15210363
Lalman JA and Komjarova I Impact of long chain fatty acids on glucose fermentation under mesophilic conditions. 2004 Environ Technol pmid:15214444
Gozes I and Fridkin M A fatty neuropeptide. Potential drug for noninvasive impotence treatment in a rat model. 1992 J. Clin. Invest. pmid:1522236
Morandi S et al. Association of sugar-based carboranes with cationic liposomes: an electron spin resonance and light scattering study. 2004 Biochim. Biophys. Acta pmid:15238258
Borden MA et al. Surface phase behavior and microstructure of lipid/PEG-emulsifier monolayer-coated microbubbles. 2004 Colloids Surf B Biointerfaces pmid:15261034
Ariga K et al. Spider-web amphiphiles as artificial lipid clusters: design, synthesis, and accommodation of lipid components at the air-water interface. 2004 Langmuir pmid:15274583
Wong DA et al. Coordination of peroxisomal beta-oxidation and fatty acid elongation in HepG2 cells. 2004 J. Biol. Chem. pmid:15277519
Fernández Cervera M et al. Determination of tackiness of chitosan film-coated pellets exploiting minimum fluidization velocity. 2004 Int J Pharm pmid:15288349
Cheng HC et al. Lipid binding in rice nonspecific lipid transfer protein-1 complexes from Oryza sativa. 2004 Protein Sci. pmid:15295114
Liao X and Wiedmann TS Characterization of pharmaceutical solids by scanning probe microscopy. 2004 J Pharm Sci pmid:15295786
Lee J Intrinsic adhesion force of lubricants to steel surface. 2004 J Pharm Sci pmid:15295791
Velegraki A et al. Use of fatty acid RPMI 1640 media for testing susceptibilities of eight Malassezia species to the new triazole posaconazole and to six established antifungal agents by a modified NCCLS M27-A2 microdilution method and Etest. 2004 J. Clin. Microbiol. pmid:15297502
Pari L and Venkateswaran S Protective role of Phaseolus vulgaris on changes in the fatty acid composition in experimental diabetes. 2004 J Med Food pmid:15298769
Il'in MM et al. Thermodynamic and functional properties of legumin (11S globulin from Vicia faba) in the presence of small-molecule surfactants: effect of temperature and pH. 2004 J Colloid Interface Sci pmid:15313639