stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Eczema, Dyshidrotic D011146 1 associated lipids
Decalcification, Pathologic D003649 1 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Infertility D007246 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Fatemi SH et al. The glycophospholipid anchor of Thy-1. Biosynthetic labeling experiments with wild-type and class E Thy-1 negative lymphomas. 1987 J. Biol. Chem. pmid:2881925
Nakanishi H et al. Comparative studies on additive effects of sodium dodecylbenzensulfonate and sodium stearate on uptake of chemicals by willow shiner (Gnathopogon caerulescens). 1987 Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. pmid:2882933
Bergquist SO et al. Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. 1987 Pediatr. Infect. Dis. J. pmid:2885802
Zara GP et al. Erythromycin and gastrointestinal motility. 1987 Lancet pmid:2889954
West AA et al. The relationship between glycosyltransferase production and membrane fatty acid composition of Streptococcus sanguis NCTC 7865 grown in the presence of protonmotive force inhibitors. 1987 J. Gen. Microbiol. pmid:2966234
Halát G et al. Effects of incomplete ischemia and subsequent recirculation on free palmitate, stearate, oleate and arachidonate levels in lumbar and cervical spinal cord of rabbit. 1987 Gen. Physiol. Biophys. pmid:3117617
Hohl C and Rösen P Arachidonic acid metabolism in isolated rat heart myocytes. 1987 Prog. Clin. Biol. Res. pmid:3118380
Taylor AJ et al. An alternative explanation for the changes in erythrocyte fatty acids observed in diabetes mellitus. 1987 Clin. Chem. pmid:3119255
Shanson DC Antibiotic prophylaxis of infective endocarditis in the United Kingdom and Europe. 1987 J. Antimicrob. Chemother. pmid:3119557
Dudley DT et al. Depletion of arachidonic acid from GH3 cells. Effects on inositol phospholipid turnover and cellular activation. 1987 Biochem. J. pmid:3120699
Faden AI et al. Alterations in lipid metabolism, Na+,K+-ATPase activity, and tissue water content of spinal cord following experimental traumatic injury. 1987 J. Neurochem. pmid:3033150
Imai A and Gershengorn MC Measurement of lipid turnover in response to thyrotropin-releasing hormone. 1987 Meth. Enzymol. pmid:3037241
Feix JB et al. Interactions of 14N:15N stearic acid spin-label pairs: effects of host lipid alkyl chain length and unsaturation. 1987 Biochemistry pmid:2820479
Roughan PG et al. Metabolism of exogenous long-chain fatty acids by spinach leaves. 1987 Arch. Biochem. Biophys. pmid:3426240
Rhoads DE et al. Metabolism of saturated fatty acids by Paramecium tetraurelia. 1987 J. Lipid Res. pmid:3430068
Tonnet ML and Green AG Characterization of the seed and leaf lipids of high and low linolenic acid flax genotypes. 1987 Arch. Biochem. Biophys. pmid:3813554
Ong DE et al. Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine. 1987 J. Biol. Chem. pmid:3818619
Berlin E et al. Influence of saturated and unsaturated fats on platelet fatty acids in cholesterol-fed rabbits. 1987 Atherosclerosis pmid:3827974
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Hasin Y et al. Dietary lipid intake and myocardial electrophysiology. 1987 Isr. J. Med. Sci. pmid:3440741
Cutler RR et al. The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. 1987 Tubercle pmid:3448797
Matsui MS and Jeffrey AM Fatty acid modification of C3H 10T 1/2 fibroblast cells: changes in benzo(a)pyrene metabolism and phorbol ester binding. 1987 Cancer Res. pmid:3471326
Bridges CD et al. Rhodopsin, vitamin A, and interstitial retinol-binding protein in the rd chicken. 1987 Invest. Ophthalmol. Vis. Sci. pmid:3557867
Hope MJ and Cullis PR Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. 1987 J. Biol. Chem. pmid:3558410
Husebye ES and Flatmark T Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. 1987 Biochim. Biophys. Acta pmid:3607074
Cavalleri A and Minoia C Lead level of whole blood and plasma in workers exposed to lead stearate. 1987 Scand J Work Environ Health pmid:3616550
Seimiya T et al. Effects of composition and molecular packing on ionic properties of lipid monolayer having both cationic and anionic head groups. 1987 Chem. Phys. Lipids pmid:3621383
Salminen S and Salminen E Urinary excretion of orally administered oxalic acid in MYRJ 45-treated NMRI mice. 1987 Toxicol. Lett. pmid:3590233
Masuzawa Y et al. Distribution of dietary trans-octadecenoate among acyl-CoA and other lipid fractions of rat liver and heart. 1987 Biochim. Biophys. Acta pmid:3593750
Kolesnick RN and Paley AE 1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action. 1987 J. Biol. Chem. pmid:3597411
Habib NA et al. Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas. 1987 Int J Colorectal Dis pmid:3598325
Pyörälä S Effect of some vehicles used in intramammary mastitis preparations on inflammation indicators in milk. 1987 J. Vet. Pharmacol. Ther. pmid:3656512
Emken EA et al. Metabolism in humans of cis-12,trans-15-octadecadienoic acid relative to palmitic, stearic, oleic and linoleic acids. 1987 Lipids pmid:3306237
Dinman BD Aluminum in the lung: the pyropowder conundrum. 1987 J Occup Med pmid:3316541
Hattori T et al. Membrane phospholipid composition and membrane fluidity of human brain tumour: a spin label study. 1987 Neurol. Res. pmid:2883605
Søreide O et al. Inadequacy of oleic acid in erythrocytes as a marker of malignancies. 1987 Br Med J (Clin Res Ed) pmid:3103770
McCormack WM et al. Effect on birth weight of erythromycin treatment of pregnant women. 1987 Obstet Gynecol pmid:3543767
Kringsholm B and Christoffersen P The nature and the occurrence of birefringent material in different organs in fatal drug addiction. 1987 May-Jun Forensic Sci. Int. pmid:3036675
Udod VM et al. [Microbial breakdown of stearox-6 and a study of the genetic determination of the nature of the degradative activity]. 1987 May-Jun Mikrobiol. Zh. pmid:3150493
Shani J et al. Efficacy of sustained-release radioprotective drugs in vivo. 1987 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:2966504
Loscalzo J et al. Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. 1987 Sep-Oct Arteriosclerosis pmid:3675304
Huang G et al. Identification of the thiol ester linked lipids in apolipoprotein B. 1988 Biochemistry pmid:3365394
Periquet B et al. Fatty acid composition and kinetic behaviour of liver retinyl esters in vitamin A sufficient and deficient rats. 1988 Clin. Chim. Acta pmid:3370842
Brodersen R et al. Palmitate binding to serum albumin, measured by rate of dialysis. 1988 Eur. J. Biochem. pmid:3371363
Slinger AJ and Isaac RE Synthesis of apolar ecdysone esters by ovaries of the cockroach Periplaneta americana. 1988 Gen. Comp. Endocrinol. pmid:3371652
Sparace SA et al. A preliminary analysis of Fatty Acid synthesis in pea roots. 1988 Plant Physiol. pmid:16666088