| MeSH term | MeSH ID | Detail |
|---|---|---|
| Eczema, Dyshidrotic | D011146 | 1 associated lipids |
| Decalcification, Pathologic | D003649 | 1 associated lipids |
| Salivary Duct Calculi | D012465 | 2 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Calculi | D002137 | 3 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Obesity, Abdominal | D056128 | 3 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Christensen E et al. | Beta-oxidation of medium chain (C8-C14) fatty acids studied in isolated liver cells. | 1989 | Biochim. Biophys. Acta | pmid:2752017 |
| Collins JM and Grogan WM | Comparison between flow cytometry and fluorometry for the kinetic measurement of membrane fluidity parameters. | 1989 | Cytometry | pmid:2917474 |
| Garcia Zevallos M and Farkas T | Manipulation of plasma membrane physical state affects desaturase activity in rat lymphocytes. | 1989 | Arch. Biochem. Biophys. | pmid:2786374 |
| Singh H et al. | Mitochondrial and peroxisomal beta-oxidation of stearic and lignoceric acids by rat brain. | 1989 | J. Neurochem. | pmid:2809586 |
| Burrows GE et al. | A comparison of the various routes of administration of erythromycin in cattle. | 1989 | J. Vet. Pharmacol. Ther. | pmid:2810478 |
| Wada M et al. | Mechanism of biosynthesis of unsaturated fatty acids in Pseudomonas sp. strain E-3, a psychrotrophic bacterium. | 1989 | J. Bacteriol. | pmid:2753856 |
| Friedman E et al. | Fecal diglycerides as selective endogenous mitogens for premalignant and malignant human colonic epithelial cells. | 1989 | Cancer Res. | pmid:2910475 |
| Demediuk P et al. | Changes in free fatty acids, phospholipids, and cholesterol following impact injury to the rat spinal cord. | 1989 | J. Neurosci. Res. | pmid:2520534 |
| Yoshida S et al. | Effect of phospholipase A2 and free fatty acids on lipid-protein interactions in long- and very-long-chain fatty acyl-CoA elongation enzyme systems of brain microsomes. | 1989 | Biochim. Biophys. Acta | pmid:2502180 |
| Wolf BA et al. | Secretagogue-induced diacylglycerol accumulation in isolated pancreatic islets. Mass spectrometric characterization of the fatty acyl content indicates multiple mechanisms of generation. | 1989 | Biochemistry | pmid:2504278 |
| Furr HC et al. | The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat. | 1989 | J. Nutr. | pmid:2703916 |
| Thiel C and Kadenbach B | Influence of non-esterified fatty acids on respiratory control of reconstituted cytochrome-c oxidase. | 1989 | FEBS Lett. | pmid:2546826 |
| Yodono H et al. | [A case of hepatocellular carcinoma effectively treated by intraarterial infusion of CDDP and other agents]. | 1989 | Gan To Kagaku Ryoho | pmid:2551253 |
| Buttke TM et al. | Absence of unsaturated fatty acid synthesis in murine T lymphocytes. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2569740 |
| Beardshall K et al. | Saturation of fat and cholecystokinin release: implications for pancreatic carcinogenesis. | 1989 | Lancet | pmid:2572741 |
| Hillered L and Chan PH | Brain mitochondrial swelling induced by arachidonic acid and other long chain free fatty acids. | 1989 | J. Neurosci. Res. | pmid:2531232 |
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| Rendu F et al. | Ajoene, the antiplatelet compound derived from garlic, specifically inhibits platelet release reaction by affecting the plasma membrane internal microviscosity. | 1989 | Biochem. Pharmacol. | pmid:2539823 |
| Fenner GP and Parks LW | Gas chromatographic analysis of intact steryl esters in wild type Saccharomyces cerevisiae and in an ester accumulating mutant. | 1989 | Lipids | pmid:2674578 |
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| Williams RO and McGinity JW | Compaction properties of microcrystalline cellulose and sodium sulfathiazole in combination with talc or magnesium stearate. | 1989 | J Pharm Sci | pmid:2614693 |
| Kaukoranta-Tolvanen SS et al. | Effect of erythromycin acistrate and erythromycin stearate on human colonic microflora. | 1989 | Scand. J. Infect. Dis. | pmid:2617212 |
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| Linden DJ and Routtenberg A | cis-Fatty acids, which activate protein kinase C, attenuate Na+ and Ca2+ currents in mouse neuroblastoma cells. | 1989 | J. Physiol. (Lond.) | pmid:2559978 |
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| Sharma BK and Erdman RA | In vitro degradation of choline from selected feedstuffs and choline supplements. | 1989 | J. Dairy Sci. | pmid:2600236 |
| Punnonen K and Jansén CT | UVB irradiation and distribution of arachidonic acid (20:4) and stearic acid (18:0) in human keratinocytes. | 1989 | Photodermatol | pmid:2473452 |
| Pahuja SL and Hochberg RB | A comparison of the fatty acid esters of estradiol and corticosterone synthesized by tissues of the rat. | 1989 | J. Biol. Chem. | pmid:2492532 |
| Shires SE et al. | Effects of linoleic acid and mitogenic stimulation on the fatty acid composition of human lymphocytes. | 1989 | Biochim. Biophys. Acta | pmid:2493807 |
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| Broderick PA | Characterizing stearate probes in vitro for the electrochemical detection of dopamine and serotonin. | 1989 | Brain Res. | pmid:2776030 |
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| Männistö PT et al. | Efficacy of erythromycin acistrate (2'-acetyl erythromycin stearate) and erythromycin stearate in experimental infections in mice. | 1989 | J. Pharmacol. Exp. Ther. | pmid:2778707 |
| Paris A and Rao D | Biosynthesis of estradiol-17 beta fatty acyl esters by microsomes derived from bovine liver and adrenals. | 1989 | J. Steroid Biochem. | pmid:2779237 |
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| Bentejac M et al. | Utilization of high-density lipoprotein sphingomyelin by the developing and mature brain in the rat. | 1989 | J. Neurochem. | pmid:2709013 |
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| Brodersen R et al. | Serum albumin binding of palmitate and stearate. Multiple binding theory for insoluble ligands. | 1989 | Eur. J. Biochem. | pmid:2731550 |
| Beck JC et al. | Growth of epithelium from a preneoplastic mammary outgrowth in response to mammary adipose tissue. | 1989 | In Vitro Cell. Dev. Biol. | pmid:2732196 |
| Yamreudeewong W et al. | Effect of antacid coadministration on the bioavailability of erythromycin stearate. | 1989 | Clin Pharm | pmid:2743731 |
| Skrede S et al. | The effects of alkylthioacetic acids (3-thia fatty acids) on fatty acid metabolism in isolated hepatocytes. | 1989 | Biochim. Biophys. Acta | pmid:2804058 |