| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| pmid:9608395 | ||||
| Luo L et al. | Polyoxyethylene 40 stearate modulates multidrug resistance and enhances antitumor activity of vinblastine sulfate. | 2007 | AAPS J | pmid:18170979 |
| Kuppuswamy R et al. | Estimation of capping incidence by indentation fracture tests. | 2001 | AAPS PharmSci | pmid:11741256 |
| Otsuka M et al. | Comparative evaluation of tableting compression behaviors by methods of internal and external lubricant addition: inhibition of enzymatic activity of trypsin preparation by using external lubricant addition during the tableting compression process. | 2001 | AAPS PharmSci | pmid:11741271 |
| Shah RB et al. | Comparative evaluation of flow for pharmaceutical powders and granules. | 2008 | AAPS PharmSciTech | pmid:18446489 |
| Darole PS et al. | Formulation and evaluation of microemulsion based delivery system for amphotericin B. | 2008 | AAPS PharmSciTech | pmid:18446472 |
| Gupta A et al. | Difference in the lubrication efficiency of bovine and vegetable-derived magnesium stearate during tabletting. | 2009 | AAPS PharmSciTech | pmid:19390976 |
| Zhou QT et al. | Effect of surface coating with magnesium stearate via mechanical dry powder coating approach on the aerosol performance of micronized drug powders from dry powder inhalers. | 2013 | AAPS PharmSciTech | pmid:23196863 |
| Mir VG et al. | Application of crustacean chitin as a co-diluent in direct compression of tablets. | 2010 | AAPS PharmSciTech | pmid:20238188 |
| Lakio S et al. | Challenges in detecting magnesium stearate distribution in tablets. | 2013 | AAPS PharmSciTech | pmid:23378252 |
| Räsänen E et al. | A new method to predict flowability using a microscale fluid bed. | 2003 | AAPS PharmSciTech | pmid:15198548 |
| Li S et al. | Preparation, characterization, pharmacokinetics and tissue distribution of solid lipid nanoparticles loaded with tetrandrine. | 2011 | AAPS PharmSciTech | pmid:21811889 |
| Waters LJ et al. | Controlled microwave processing applied to the pharmaceutical formulation of ibuprofen. | 2011 | AAPS PharmSciTech | pmid:21842309 |
| Khan FN and Dehghan MH | Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. | 2011 | AAPS PharmSciTech | pmid:21879394 |
| Fernández EG et al. | Rapid development and optimization of tablet manufacturing using statistical tools. | 2008 | AAPS PharmSciTech | pmid:18459048 |
| Chang CK et al. | Roller compaction, granulation and capsule product dissolution of drug formulations containing a lactose or mannitol filler, starch, and talc. | 2008 | AAPS PharmSciTech | pmid:18459052 |
| Kumar R and Sinha VR | Lipid Nanocarrier: an Efficient Approach Towards Ocular Delivery of Hydrophilic Drug (Valacyclovir). | 2017 | AAPS PharmSciTech | pmid:27368921 |
| Spaniol B et al. | Compressional behavior of a mixture of granules containing high load of Phyllanthus niruri spray-dried extract and granules of adjuvants: comparison between eccentric and rotary tablet machines. | 2009 | AAPS PharmSciTech | pmid:19662537 |
| Ahmed TA et al. | Miconazole nitrate oral disintegrating tablets: in vivo performance and stability study. | 2012 | AAPS PharmSciTech | pmid:22585373 |