stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Noker PE et al. Metabolism of 14C-labelled sucrose esters of stearic acid in rats. 1997 Food Chem. Toxicol. pmid:9225017
Dhillon HS et al. Time course of changes in lactate and free fatty acids after experimental brain injury and relationship to morphologic damage. 1997 Exp. Neurol. pmid:9225757
Yamamoto A and Kawashima Y Perfluorodecanoic acid enhances the formation of oleic acid in rat liver. 1997 Biochem. J. pmid:9230124
Khomutov GB et al. Interaction of copper ions with stearic acid Langmuir monolayers and formation of cluster structures in monolayers and Langmuir-Blodgett films. 1997 Membr Cell Biol pmid:9231365
Sparks JD et al. Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells. 1997 Biochim. Biophys. Acta pmid:9233686
Alvarez-Ortega R et al. Characterization of polar and nonpolar seed lipid classes from highly saturated fatty acid sunflower mutants. 1997 Lipids pmid:9270974
Wagner K et al. Influence of duodenal infusion of nicotinic acid on the milk fat composition of dairy cows. 1997 Arch Tierernahr pmid:9272222
Moers A and Schrezenmeir J Palmitic acid but not stearic acid inhibits NO-production in endothelial cells. 1997 Exp. Clin. Endocrinol. Diabetes pmid:9288552
West RR and Stafford DA Occupational exposures and haematological abnormalities among ordnance factory workers: a case control study. 1997 Leuk. Res. pmid:9301689
Bondarenko LB et al. Fatty acids hydroxamic derivatives as inhibitors of 5-lipoxygenase. 1997 Adv. Exp. Med. Biol. pmid:9321992