stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Morkhade DM et al. PEGylated rosin derivatives: novel microencapsulating materials for sustained drug delivery. 2007 AAPS PharmSciTech pmid:17622122
Navaneethan CV et al. Application of powder rheometer to determine powder flow properties and lubrication efficiency of pharmaceutical particulate systems. 2005 AAPS PharmSciTech pmid:16353997
Gupta A et al. Difference in the lubrication efficiency of bovine and vegetable-derived magnesium stearate during tabletting. 2009 AAPS PharmSciTech pmid:19390976
Mir VG et al. Application of crustacean chitin as a co-diluent in direct compression of tablets. 2010 AAPS PharmSciTech pmid:20238188
Cunha TA et al. Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. 2013 AAPS PharmSciTech pmid:23897034
Räsänen E et al. A new method to predict flowability using a microscale fluid bed. 2003 AAPS PharmSciTech pmid:15198548
Khan FN and Dehghan MH Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. 2011 AAPS PharmSciTech pmid:21879394
Spaniol B et al. Compressional behavior of a mixture of granules containing high load of Phyllanthus niruri spray-dried extract and granules of adjuvants: comparison between eccentric and rotary tablet machines. 2009 AAPS PharmSciTech pmid:19662537
Thotakura N et al. Chitosan-Stearic Acid Based Polymeric Micelles for the Effective Delivery of Tamoxifen: Cytotoxic and Pharmacokinetic Evaluation. 2017 AAPS PharmSciTech pmid:27287243
Schrank S et al. Ibuprofen-loaded calcium stearate pellets: drying-induced variations in dosage form properties. 2012 AAPS PharmSciTech pmid:22552931