stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
KIVITS M [Frambesia therapy with oil procaine-penicillin with aluminium stearate]. 1951 Ann Soc Belg Med Trop (1920) pmid:14838448
WEITZEL G and WOJAHN J [Biochemistry of branched carboxylic acids. VII. Preparation of racemic monomethyl-stearic acids]. 1951 Hoppe-Seyler's Z. Physiol. Chem. pmid:14860764
WEINMAN EO et al. Conversion of first and sixth carbons of stearic acid to carbon dioxide by rats. 1951 J. Biol. Chem. pmid:14861197
BERNHARD K and GLOOR U [Some other fatty acids with vitamin F effect]. 1953 Helv Physiol Pharmacol Acta pmid:13128629
MUNZEL K and AMMANN R [On the washable fat-in-water ointments. I. Description and characteristics of fat-in-water ointments]. 1953 Pharm Acta Helv pmid:13133659
DOXIADIS SA Procaine penicillin with aluminium monostearate; infrequent injections for children. 1953 Lancet pmid:13085786
VALADE P and COSTE E [Toxicity of the organic lead salts; experimental study]. 1953 Arch Mal Prof pmid:13149301
BUTCHER EO Penetration of radioactive stearic acid into the skin of the rat. 1953 J. Invest. Dermatol. pmid:13096866
SKOU JC Local anaesthetics. V. The action of local anaesthetics on monomolecular layers of stearic acid. 1954 Acta Pharmacol Toxicol (Copenh) pmid:14398295
CSIPKE Z [Advanced training in prescription filling]. 1954 Gyogyszeresz pmid:24551927