stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Zackler J et al. A mass screening program for the detection of gonorrhea. 1972 Am. J. Obstet. Gynecol. pmid:4623083
Wahle KW and Garton GA Desaturation of stearate by sheep tissue microsomal preparations. 1972 Biochem. J. pmid:4643297
Conte U et al. The effect of magnesium stearate and polytetrafluoroethylene as lubricants in direct compression of acetylsalicylic acid. 1972 Farmaco Prat pmid:5049531
Price CJ and Rowe CE Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. 1972 Biochem. J. pmid:5075269
Patil GS et al. Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. 1972 J. Lipid Res. pmid:5075503
Kannangara CG and Stumpf PK Fat Metabolism in Higher Plants: XLVII. The Effect of Nitrite and Other Anions on the Formation of Unsaturated Fatty Acids by Isolated Chloroplasts. 1972 Plant Physiol. pmid:16657990
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. 1972 Yakugaku Zasshi pmid:4675495
Butcher AE and Jones TM Some physical characteristics of magnesium stearate. 1972 J. Pharm. Pharmacol. pmid:4144914
McLeay AC and Beveridge J Clinical trial of erythromycin stearate suspension. 1971 Med. J. Aust. pmid:4929585
Schmidt P et al. [Acute inhalation toxicity of cadmium stearate]. 1971 Z Gesamte Hyg pmid:5123074
Caille MP et al. [Acute forms of lead poisoning by lead stearate]. 1971 Arch Mal Prof pmid:5123552
Bell SM A comparison of absorption after oral administration of erythromycin estolate and erythromycin stearate. 1971 Med. J. Aust. pmid:5134726
Givan CV and Stumpf PK Fat Metabolism in Higher Plants: XLV. Some Factors Regulating Fatty Acid Synthesis by Isolated Spinach Chloroplasts. 1971 Plant Physiol. pmid:16657651
Smith DD Clinical trial of erythromycin stearate suspension. 1971 Med. J. Aust. pmid:5577264
Carlisle HN and Saslaw S Therapy of staphylococcal infections in monkeys. VI. Comparison of clindamycin, erythromycin, and methicillin. 1971 Appl Microbiol pmid:4994902
Nossel HL et al. Inhibition of collagen-induced platelet aggregation by normal plasma. 1971 J. Clin. Invest. pmid:4107268
SHABANOVA IA MYOCARDIAL FATTY ACIDS IN NORMAL RABBITS AND RABBITS WITH EXPERIMENTAL MYOCARDITIS. 1965 Mar-Apr Fed Proc Transl Suppl pmid:14304768
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WINTER CA and FLATAKER L NOCICEPTIVE THRESHOLDS AS AFFECTED BY PARENTERAL ADMINISTRATION OF IRRITANTS AND OF VARIOUS ANTINOCICEPTIVE DRUGS. 1965 J. Pharmacol. Exp. Ther. pmid:14334273
DICOSTANZO G and CLEMENT J ["IN VIVO" INCORPORATION OF TRITIATED OLEIC, STEARIC AND PALMITIC ACIDS INTO LIPIDS OF RAT INTESTINAL LUMEN AND MUCOSA. IMPORTANCE OF SUPPLY OF ENDOGENOUS FATTY ACIDS]. 1965 Bull. Soc. Chim. Biol. pmid:14334811
SRIDHARA S and BHAT JV FURTHER INVESTIGATIONS OF THE INCORPORATION OF (1-14C)ACETATE INTO THE LIPIDS OF THE SILKWORM BOMBYX MORI L. 1965 Biochem. J. pmid:14340061
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KANFER J OBSERVATIONS ON CEREBROSIDE METABOLISM IN VIVO. 1965 J. Biol. Chem. pmid:14275111
KEITEL HG and CHU E PREMATURE INFANT FEEDING. I. THE CLINICAL USEFULNESS OF CALORIC CONCENTRATION OF FORMULAS, OF EARLY VERSUS LATE FEEDINGS AND OF LOW STEARIC ACID CONTENT FORMULAS. 1965 Pediatr. Clin. North Am. pmid:14276882
KORN ED et al. SYNTHESIS OF UNSATURATED FATTY ACIDS IN THE SLIME MOLD PHYSARUM POLYCEPHALUM AND THE ZOOFLAGELLATES LEISHMANIA TARENTOLAE, TRYPANOSOMA LEWISI, AND CRITHIDIA SP.: A COMPARATIVE STUDY. 1965 J. Lipid Res. pmid:14280472
BACHUR NR et al. FATTY ACID AMIDES OF ETHANOLAMINE IN MAMMALIAN TISSUES. 1965 J. Biol. Chem. pmid:14284696
HANSEN HJ et al. THE EFFECT OF WHOLE-BODY X-IRRADIATION ON THE SYNTHESIS OF INDIVIDUAL FATTY ACIDS IN LIVER SLICES FROM NORMAL AND FASTED RATS. 1965 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:14309652
LAMBREMONT EN BIOSYNTHESIS OF FATTY ACIDS IN ASEPTICALLY REARED INSECTS. 1965 Comp. Biochem. Physiol. pmid:14314981
ANSTALL HB and TRUJILLO JM DETERMINATION OF FREE FATTY ACIDS IN PLASMA BY A COLORIMETRIC PROCEDURE: AN APPRAISAL OF THE METHOD AND COMPARISON WITH OTHER TECHNICS. 1965 Clin. Chem. pmid:14319230
SHAFRIR E et al. PARTITION OF FATTY ACIDS OF 20-24 CARBON ATOMS BETWEEN SERUM ALBUMIN AND LIPOPROTEINS. 1965 Biochim. Biophys. Acta pmid:14320230
GOERANSSON G THE METABOLISM OF FATTY ACIDS IN THE RAT. IV. STEARIC ACID. 1965 Acta Physiol. Scand. pmid:14321752
BRZIN B COMPARATIVE STUDIES ON ANAEROBIC CORYNEBACTERIA AND ACTINOMYCETES. 1965 Acta Pathol Microbiol Scand pmid:14322324
NORKIN SA et al. EFFECT OF ALBUMIN AND FATTY ACIDS ON CELLULAR GROWTH IN VITRO. 1965 Arch Pathol pmid:14322948
VADEHRA DV and HARMON LG ACTION OF LIPASES OF STAPHYLOCOCCUS AUREUS ON MILK FAT. 1965 Appl Microbiol pmid:14325270
ELOVSON J CHAIN-SHORTENING OF STEARIC ACID IN THE INTACT RAT. 1965 Biochim. Biophys. Acta pmid:14290835
BOYD EN et al. IRRELATION OF KETO STEARIC ACIDS TO FATTY ACID METABOLISM IN THE RUMINANT MAMMARY GLAND. 1965 J. Dairy Sci. pmid:14292229
MCCARTHY RD et al. THE CONVERSION OF STEARIC ACID TO OLEIC IN FRESHLY SECRETED MILK. 1965 Biochim. Biophys. Acta pmid:14292868
SCHROEPFER GJ ENZYMATIC STEREOSPECIFICITY IN THE CONVERSION OF OLEIC ACID TO 10-HYDROXYSTERARIC ACID. 1965 J. Am. Chem. Soc. pmid:14293763
SNYDER F and WRIGHT R EFFECT OF LOCALIZED IRRADIATION ON THE METABOLISM OF BONE-MARROW LIPIDS. 1965 Radiat. Res. pmid:14295131
Keys A et al. Serum cholesterol response to changes in the diet: IV. Particular saturated fatty acids in the diet. 1965 Metab. Clin. Exp. pmid:25286466