stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Florin-Christensen J et al. Phosphatidylcholine formation is the predominant lipid biosynthetic event in the hemoparasite Babesia bovis. 2000 Mol. Biochem. Parasitol. pmid:10743618
Plötz BM et al. Characterization of a novel lipid A containing D-galacturonic acid that replaces phosphate residues. The structure of the lipid a of the lipopolysaccharide from the hyperthermophilic bacterium Aquifex pyrophilus. 2000 J. Biol. Chem. pmid:10753930
Ahrabi SF et al. Influence of neutron activation factors on matrix tablets for site specific delivery to the colon. 2000 Eur J Pharm Sci pmid:10767600
Swaminathan V and Kildsig DO The effect of particle morphology on the physical stability of pharmaceutical powder mixtures: the effect of surface roughness of the carrier on the stability of ordered mixtures. 2000 Drug Dev Ind Pharm pmid:10769777
Schmider W et al. Transport of heptafluorostearate across model membranes. Membrane transport of long-chain fatty acid anions I. 2000 J. Lipid Res. pmid:10787438
Wissing S et al. An investigation into the use of stepwise isothermal high sensitivity DSC as a means of detecting drug-excipient incompatibility. 2000 Int J Pharm pmid:10802407
Min Y et al. Pregnancy reduces arachidonic and docosahexaenoic in plasma triacylglycerols of Korean women. 2000 Int J Vitam Nutr Res pmid:10804459
Pignatello R et al. In vitro release kinetics of Tolmetin from tabletted Eudragit microparticles. 2000 May-Jun J Microencapsul pmid:10819424
Tsuda K et al. Role of insulin in the regulation of membrane fluidity of erythrocytes in essential hypertension: an electron paramagnetic resonance investigation. 2000 Am. J. Hypertens. pmid:10821339
Aguilella VM et al. Double layer potential and degree of dissociation in charged lipid monolayers. 2000 Chem. Phys. Lipids pmid:10823470