| MeSH term | MeSH ID | Detail |
|---|---|---|
| Obesity, Abdominal | D056128 | 3 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Yaws | D015001 | 4 associated lipids |
| Whooping Cough | D014917 | 6 associated lipids |
| Vitamin E Deficiency | D014811 | 29 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shazly GA | Ciprofloxacin Controlled-Solid Lipid Nanoparticles: Characterization, In Vitro Release, and Antibacterial Activity Assessment. | 2017 | Biomed Res Int | pmid:28194408 |
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| Yamamoto K et al. | Effect of Magnesium Stearate Mono- and Dihydrate Dispersibilities on Physical Properties of Tablets. | 2017 | Chem. Pharm. Bull. | pmid:29093289 |
| Heim CB and Gillman JD | Genotyping-by-Sequencing-Based Investigation of the Genetic Architecture Responsible for a ∼Sevenfold Increase in Soybean Seed Stearic Acid. | 2017 | G3 (Bethesda) | pmid:27866151 |
| Anbalagan P et al. | Influence of the Punch Head Design on the Physical Quality of Tablets Produced in a Rotary Press. | 2017 | J Pharm Sci | pmid:27842972 |
| Delaney SP et al. | Characterization of Synthesized and Commercial Forms of Magnesium Stearate Using Differential Scanning Calorimetry, Thermogravimetric Analysis, Powder X-Ray Diffraction, and Solid-State NMR Spectroscopy. | 2017 | J Pharm Sci | pmid:27836109 |
| Dudhipala N and Veerabrahma K | Improved anti-hyperlipidemic activity of Rosuvastatin Calcium via lipid nanoparticles: Pharmacokinetic and pharmacodynamic evaluation. | 2017 | Eur J Pharm Biopharm | pmid:27810472 |
| Song S et al. | Identification of pork flavour precursors from enzyme-treated lard using Maillard model system assessed by GC-MS and partial least squares regression. | 2017 | Meat Sci. | pmid:27792915 |
| Shilpi D et al. | Improved Stability and Enhanced Oral Bioavailability of Atorvastatin Loaded Stearic Acid Modified Gelatin Nanoparticles. | 2017 | Pharm. Res. | pmid:28466393 |
| Lakhssassi N et al. | Stearoyl-Acyl Carrier Protein Desaturase Mutations Uncover an Impact of Stearic Acid in Leaf and Nodule Structure. | 2017 | Plant Physiol. | pmid:28461402 |
| Noor NM et al. | Preparation and characterization of dutasteride-loaded nanostructured lipid carriers coated with stearic acid-chitosan oligomer for topical delivery. | 2017 | Eur J Pharm Biopharm | pmid:28412472 |
| Sapra M et al. | Engineering of layered, lipid-encapsulated drug nanoparticles through spray-drying. | 2017 | Colloids Surf B Biointerfaces | pmid:28340484 |
| Lee W et al. | Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis. | 2017 | Sci Rep | pmid:28250431 |
| Crowley ME et al. | Near-infrared monitoring of roller compacted ribbon density: Investigating sources of variation contributing to noisy spectral data. | 2017 | Eur J Pharm Sci | pmid:28216342 |
| Lau M et al. | Investigation into the Manufacture and Properties of Inhalable High-Dose Dry Powders Produced by Comilling API and Lactose with Magnesium Stearate. | 2017 | AAPS PharmSciTech | pmid:28070849 |
| Zhou Y et al. | An oxygen slow-releasing material and its application in water remediation as oxygen supplier. | 2017 | Environ Technol | pmid:28041538 |
| Ocloo FCK et al. | Effects of stearic acid and gamma irradiation, alone and in combination, on pasting properties of high amylose maize starch. | 2016 | Food Chem | pmid:26212935 |
| Patadia R et al. | Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets. | 2016 | Pharm Dev Technol | pmid:25566928 |
| Teh SS et al. | Incorporation of Palmitic Acid or Stearic Acid into Soybean Oils Using Enzymatic Interesterification. | 2016 | J Oleo Sci | pmid:27477075 |
| Sun Y et al. | Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study. | 2016 | J. Lipid Res. | pmid:27371261 |
| Du H et al. | Modification of the fatty acid composition in Arabidopsis and maize seeds using a stearoyl-acyl carrier protein desaturase-1 (ZmSAD1) gene. | 2016 | BMC Plant Biol. | pmid:27297560 |
| Sorigué D et al. | Microalgae Synthesize Hydrocarbons from Long-Chain Fatty Acids via a Light-Dependent Pathway. | 2016 | Plant Physiol. | pmid:27288359 |
| Jeyanathan J et al. | Biohydrogenation of 22:6n-3 by Butyrivibrio proteoclasticus P18. | 2016 | BMC Microbiol. | pmid:27283157 |
| Hashemi Goradel N et al. | Improvement of Liver Cell Therapy in Rats by Dietary Stearic Acid. | 2016 | Iran. Biomed. J. | pmid:27090202 |
| Ma Y et al. | Silymarin-Loaded Nanoparticles Based on Stearic Acid-Modified Bletilla striata Polysaccharide for Hepatic Targeting. | 2016 | Molecules | pmid:26938513 |
| Šrámek J et al. | p38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells. | 2016 | Int J Mol Sci | pmid:26861294 |
| Cerf ME and Herrera E | High Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat. | 2016 | Nutrients | pmid:26742067 |
| Fretts AM et al. | Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length. | 2016 | J. Nutr. | pmid:26701797 |
| Mazel V et al. | Reevaluation of the diametral compression test for tablets using the flattened disc geometry. | 2016 | Int J Pharm | pmid:27702696 |
| Nie H et al. | Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in Solid-State Formulations. | 2016 | Mol. Pharm. | pmid:27542728 |
| Passerini N et al. | Development of microparticles for oral administration of the non-conventional radical scavenger IAC and testing in an inflammatory rat model. | 2016 | Int J Pharm | pmid:27530293 |
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| Ghate VM et al. | Nanostructured lipid carriers for the topical delivery of tretinoin. | 2016 | Eur J Pharm Biopharm | pmid:27519827 |
| Ohiri RC and Bassey EE | Gas Chromatography-Mass Spectrometry Analysis of Constituent Oil from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), from Nigeria. | 2016 | Int J Med Mushrooms | pmid:27481303 |
| Monteyne T et al. | Stearic acid and high molecular weight PEO as matrix for the highly water soluble metoprolol tartrate in continuous twin-screw melt granulation. | 2016 | Int J Pharm | pmid:27452420 |
| Ariyasu A et al. | Delay effect of magnesium stearate on tablet dissolution in acidic medium. | 2016 | Int J Pharm | pmid:27444551 |
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| Zhang Y et al. | CO2/pH-Controllable Viscoelastic Nanostructured Fluid Based on Stearic Acid Soap and Bola-Type Quaternary Ammonium Salt. | 2016 | Langmuir | pmid:26907546 |
| Wang S et al. | Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. | 2016 | Biochem. Biophys. Res. Commun. | pmid:26879142 |
| Lohan SB et al. | Investigation of cutaneous penetration properties of stearic acid loaded to dendritic core-multi-shell (CMS) nanocarriers. | 2016 | Int J Pharm | pmid:26853315 |
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