stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
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What genes are associated with stearic acid?
Related references are published most in these journals:
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hundrieser KE et al. | Distribution of trans-octadecenoic acid in the major glycerolipids of human milk. | 1983 | J. Pediatr. Gastroenterol. Nutr. | pmid:6644446 |
| Hikal AH | Dissolution of meprobamate from various tablet formulations. | 1983 | Pharmazie | pmid:6669616 |
| Kohn MC and Garfinkel D | Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation. | 1983 | Ann Biomed Eng | pmid:6592996 |
| Duncan MO et al. | Treatment of chancroid with erythromycin. A clinical and microbiological appraisal. | 1983 | Br J Vener Dis | pmid:6603249 |
| Upreti GC et al. | Membrane lipids of hepatic tissue. I. Neutral lipids from subcellular fractions of liver and hepatoma 7288CTC. | 1983 | J. Natl. Cancer Inst. | pmid:6572743 |
| Erman A et al. | Phospholipase A2 inhibitors. Differential inhibition of fatty acid acylation into kidney lipids by mepacrine and p-bromophenacyl bromide. | 1983 | Biochem. Pharmacol. | pmid:6870935 |
| Flood MT et al. | Vitamin A utilization in human retinal pigment epithelial cells in vitro. | 1983 | Invest. Ophthalmol. Vis. Sci. | pmid:6885309 |
| Chien JL and Hogan EL | Novel pentahexosyl ganglioside of the globo series purified from chicken muscle. | 1983 | J. Biol. Chem. | pmid:6885798 |
| Edwards EK and Edwards EK | Allergic reaction to triethanolamine stearate in a sunscreen. | 1983 | Cutis | pmid:6831931 |
| Chapkin RS et al. | Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis. | 1983 | J. Lab. Clin. Med. | pmid:6833842 |
| Hillmar I et al. | Influence of fatty acids on microsomal diacylglycerol acyltransferase activity in primary cultures of hepatocytes. | 1983 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6840704 |
| Warrell DA et al. | Pathophysiology and immunology of the Jarisch-Herxheimer-like reaction in louse-borne relapsing fever: comparison of tetracycline and slow-release penicillin. | 1983 | J. Infect. Dis. | pmid:6842024 |
| Zeisel SH et al. | Formation of methylamines from ingested choline and lecithin. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6842395 |
| Foot M et al. | Some properties, including the substrate in vivo, of the delta 9-desaturase in Micrococcus cryophilus. | 1983 | Biochem. J. | pmid:6847622 |
| Quinn PA et al. | Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. | 1983 | Am. J. Obstet. Gynecol. | pmid:6849358 |
| Streichman S et al. | Unique profile for erythrocyte membrane acetylcholinesterase in hereditary spherocytosis. | 1983 | Biochim. Biophys. Acta | pmid:6849970 |
| Sobel JD et al. | Legionella bozemanii. Still another cause of pneumonia. | 1983 | JAMA | pmid:6854903 |
| Stults BM et al. | Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease. | 1983 | South. Med. J. | pmid:6857302 |
| Slomiany A et al. | Isolation of fatty acids covalently bound to the gastric mucus glycoprotein of normal and cystic fibrosis patients. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6860340 |
| Slomiany A et al. | Covalently linked fatty acids in gastric mucus glycoprotein of cystic fibrosis patients. | 1983 | J. Biol. Chem. | pmid:6863300 |
| Khan KA et al. | The effect of mixing time of magnesium stearate on the tableting properties of dried microcrystalline cellulose. | 1983 | Pharm Acta Helv | pmid:6867042 |
| Swendsen CL et al. | 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine: a novel source of arachidonic acid in neutrophils stimulated by the calcium ionophore A23187. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6407484 |
| Inman WH and Rawson NS | Erythromycin estolate and jaundice. | 1983 | Br Med J (Clin Res Ed) | pmid:6407653 |
| Carli F and Colombo I | Influence of porosity on the contact angle of non-wet solids. | 1983 | J. Pharm. Pharmacol. | pmid:6135790 |
| Gabriel SM and Simpkins JW | Effects of a sustained-release naloxone pellet on luteinizing hormone secretion in female rats. | 1983 | Neuroendocrinology | pmid:6139759 |
| Jacques NA | Membrane perturbation by cerulenin modulates glucosyltransferase secretion and acetate uptake by Streptococcus salivarius. | 1983 | J. Gen. Microbiol. | pmid:6229601 |
| Agrawal HC et al. | In vivo incorporation of [3H]palmitic acid into PO protein, the major intrinsic protein of rat sciatic nerve myelin. | 1983 | J. Biol. Chem. | pmid:6189827 |
| Hashisaki P et al. | Erythromycin failure in the treatment of syphilis in a pregnant woman. | 1983 Jan-Mar | Sex Transm Dis | pmid:6601848 |
| Robson HG et al. | Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis. | 1983 Jul-Sep | Sex Transm Dis | pmid:6648747 |
| Rosén C et al. | Acute otitis media in older children and adults treated with phenoxymethyl penicillin or erythromycin stearate. Bacteriological and immunological aspects. | 1983 Sep-Oct | Acta Otolaryngol. | pmid:6416018 |
| Abdulrazik M et al. | Formulation for slow release of oral radiation-protection drugs. | 1984 | Int J Nucl Med Biol | pmid:6610665 |
| Foudin L et al. | Ethanol consumption and serum lipid profiles in Sinclair(S-1) miniature swine. | 1984 | Life Sci. | pmid:6700380 |
| Kemp P et al. | The hydrogenation of some cis- and trans-octadecenoic acids to stearic acid by a rumen Fusocillus sp. | 1984 | Br. J. Nutr. | pmid:6743636 |
| Greenberg DS et al. | Fatty acid composition of lizard tissue lipids and the effects of estradiol on serum free fatty acids. | 1984 | Comp. Biochem. Physiol., B | pmid:6744817 |
| MacDonald RC et al. | Inhibition of sendai virus-induced hemolysis by long chain fatty acids. | 1984 | Virology | pmid:6324464 |
| Goldberg I et al. | Gangrene of the upper extremity following intra-arterial injection of drugs. A case report and review of the literature. | 1984 | Clin. Orthop. Relat. Res. | pmid:6380862 |
| Buttke TM and Cuchens MA | Inhibition of lymphocyte proliferation by free fatty acids. II. Toxicity of stearic acid towards phytohaemagglutinin-activated T cells. | 1984 | Immunology | pmid:6333387 |
| Walstad RA and Hellum KB | Penetration of erythromycin in respiratory tract infections. | 1984 | Acta Otolaryngol Suppl | pmid:6333775 |
| Shanson DC et al. | The pharmacokinetics and tolerance of oral erythromycin stearate compared with erythromycin ethylsuccinate: implications for preventing endocarditis. | 1984 | J. Antimicrob. Chemother. | pmid:6334070 |
| Tjandramaga TB et al. | Relative bioavailability of enteric coated pellets, stearate and ethylsuccinate formulations of erythromycin. | 1984 | Pharmacology | pmid:6334320 |
| Ohki K et al. | Effect of alpha-tocopherol on lipid peroxidation and acyl chain mobility of liver microsomes from vitamin E-difficient rat. | 1984 | J. Nutr. Sci. Vitaminol. | pmid:6092586 |
| Lem NW and Stumpf PK | In Vitro Fatty Acid Synthesis and Complex Lipid Metabolism in the Cyanobacterium, Anabaena Variabilis: II. Acyl Transfer and Complex Lipid Formation. | 1984 | Plant Physiol. | pmid:16663690 |
| Zoeller RA and Wood R | Effects of cyclopropene fatty acids on the lipid composition of the Morris hepatoma 7288C. | 1984 | Lipids | pmid:6431218 |
| Sivarajan M et al. | Regulation of intracellular arachidonate in normal and stressed endothelial cells. | 1984 | Biochim. Biophys. Acta | pmid:6433983 |
| Rosén C et al. | Acute otitis media in older children and adults treated with penicillin or erythromycin. | 1984 | Acta Otolaryngol Suppl | pmid:6437133 |
| Dixon JF and Hokin LE | Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase. | 1984 | J. Biol. Chem. | pmid:6438097 |
| Forsberg NE et al. | Roles of acetate and its interactions with glucose and lactate in cow mammary tissue. | 1984 | J. Dairy Sci. | pmid:6438200 |
| Desudchit P et al. | Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men. | 1984 | Southeast Asian J. Trop. Med. Public Health | pmid:6441265 |
| Bridges CD et al. | Visual cycle in the mammalian eye. Retinoid-binding proteins and the distribution of 11-cis retinoids. | 1984 | Vision Res. | pmid:6543481 |
| Fenyvest E et al. | Cyclodextrin polymer, a new tablet disintegrating agent. | 1984 | Pharmazie | pmid:6494226 |