stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Ocloo FCK et al. | Effects of stearic acid and gamma irradiation, alone and in combination, on pasting properties of high amylose maize starch. | 2016 | Food Chem | pmid:26212935 |
Jójárt I et al. | Study of the compressibility of chewing gum and its applicability as an oral drug delivery system. | 2016 | Pharm Dev Technol | pmid:25673279 |
Patadia R et al. | Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets. | 2016 | Pharm Dev Technol | pmid:25566928 |
Souza AF et al. | Waste Soybean Oil and Corn Steep Liquor as Economic Substrates for Bioemulsifier and Biodiesel Production by Candida lipolytica UCP 0998. | 2016 | Int J Mol Sci | pmid:27669227 |
Teh SS et al. | Incorporation of Palmitic Acid or Stearic Acid into Soybean Oils Using Enzymatic Interesterification. | 2016 | J Oleo Sci | pmid:27477075 |
Sun Y et al. | Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study. | 2016 | J. Lipid Res. | pmid:27371261 |
Du H et al. | Modification of the fatty acid composition in Arabidopsis and maize seeds using a stearoyl-acyl carrier protein desaturase-1 (ZmSAD1) gene. | 2016 | BMC Plant Biol. | pmid:27297560 |
Sorigué D et al. | Microalgae Synthesize Hydrocarbons from Long-Chain Fatty Acids via a Light-Dependent Pathway. | 2016 | Plant Physiol. | pmid:27288359 |
Jeyanathan J et al. | Biohydrogenation of 22:6n-3 by Butyrivibrio proteoclasticus P18. | 2016 | BMC Microbiol. | pmid:27283157 |
Hashemi Goradel N et al. | Improvement of Liver Cell Therapy in Rats by Dietary Stearic Acid. | 2016 | Iran. Biomed. J. | pmid:27090202 |
Ma Y et al. | Silymarin-Loaded Nanoparticles Based on Stearic Acid-Modified Bletilla striata Polysaccharide for Hepatic Targeting. | 2016 | Molecules | pmid:26938513 |
Šrámek J et al. | p38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells. | 2016 | Int J Mol Sci | pmid:26861294 |
Cerf ME and Herrera E | High Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat. | 2016 | Nutrients | pmid:26742067 |
Fretts AM et al. | Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length. | 2016 | J. Nutr. | pmid:26701797 |
Sergeant S et al. | Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. | 2016 | Br. J. Nutr. | pmid:26615716 |
Garba L et al. | Heterologous Expression of PA8FAD9 and Functional Characterization of a Δ9-Fatty Acid Desaturase from a Cold-Tolerant Pseudomonas sp. A8. | 2016 | Mol. Biotechnol. | pmid:27629791 |
Mazel V et al. | Reevaluation of the diametral compression test for tablets using the flattened disc geometry. | 2016 | Int J Pharm | pmid:27702696 |
Nie H et al. | Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in Solid-State Formulations. | 2016 | Mol. Pharm. | pmid:27542728 |
Passerini N et al. | Development of microparticles for oral administration of the non-conventional radical scavenger IAC and testing in an inflammatory rat model. | 2016 | Int J Pharm | pmid:27530293 |
Karthik S et al. | Quillaja saponin: A prospective emulsifier for the preparation of solid lipid nanoparticles. | 2016 | Colloids Surf B Biointerfaces | pmid:27521748 |
Ghate VM et al. | Nanostructured lipid carriers for the topical delivery of tretinoin. | 2016 | Eur J Pharm Biopharm | pmid:27519827 |
Ohiri RC and Bassey EE | Gas Chromatography-Mass Spectrometry Analysis of Constituent Oil from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), from Nigeria. | 2016 | Int J Med Mushrooms | pmid:27481303 |
Monteyne T et al. | Stearic acid and high molecular weight PEO as matrix for the highly water soluble metoprolol tartrate in continuous twin-screw melt granulation. | 2016 | Int J Pharm | pmid:27452420 |
Ariyasu A et al. | Delay effect of magnesium stearate on tablet dissolution in acidic medium. | 2016 | Int J Pharm | pmid:27444551 |
Schulze C et al. | A one-stage cultivation process for lipid- and carbohydrate-rich biomass of Scenedesmus obtusiusculus based on artificial and natural water sources. | 2016 | Bioresour. Technol. | pmid:27394996 |
MužÃková J and KubÃÄková A | A study of compressibility and compactibility of directly compressible tableting materials containing tramadol hydrochloride. | 2016 | Acta Pharm | pmid:27383891 |
Hu Y et al. | Sequential delivery of therapeutic agents using a rationally designed disulfide-linked glycolipid-like nanocarrier. | 2016 | Oncotarget | pmid:27825127 |
Billès E et al. | Cellulose oligomers production and separation for the synthesis of new fully bio-based amphiphilic compounds. | 2016 | Carbohydr Polym | pmid:27577903 |
Krasnou I et al. | Permeability of water and oleic acid in composite films of phase separated polypropylene and cellulose stearate blends. | 2016 | Carbohydr Polym | pmid:27516292 |
Liu L et al. | Decreasing high postprandial stearic acid in impaired fasting glucose by dietary regulation. | 2016 | Eur J Clin Nutr | pmid:26733041 |
Thilakarathna SH et al. | Investigations of in vitro bioaccessibility from interesterified stearic and oleic acid-rich blends. | 2016 | Food Funct | pmid:26961726 |
Ma F et al. | Improvement of β-TCP/PLLA biodegradable material by surface modification with stearic acid. | 2016 | Mater Sci Eng C Mater Biol Appl | pmid:26952440 |
Zhang C et al. | Design and evaluation of an innovative floating and bioadhesive multiparticulate drug delivery system based on hollow structure. | 2016 | Int J Pharm | pmid:26943975 |
Zhang Y et al. | CO2/pH-Controllable Viscoelastic Nanostructured Fluid Based on Stearic Acid Soap and Bola-Type Quaternary Ammonium Salt. | 2016 | Langmuir | pmid:26907546 |
Wang S et al. | Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. | 2016 | Biochem. Biophys. Res. Commun. | pmid:26879142 |
Lohan SB et al. | Investigation of cutaneous penetration properties of stearic acid loaded to dendritic core-multi-shell (CMS) nanocarriers. | 2016 | Int J Pharm | pmid:26853315 |
Stahlberg S et al. | Probing the Role of Ceramide Headgroup Polarity in Short-Chain Model Skin Barrier Lipid Mixtures by ²H Solid-State NMR Spectroscopy. | 2016 | Langmuir | pmid:26828109 |
Lavergne SN et al. | Potential cutaneous hypersensitivity reaction to an inactive ingredient of thyroid hormone supplements in a dog. | 2016 | Vet. Dermatol. | pmid:26748887 |
Baig MS et al. | Application of Box-Behnken design for preparation of levofloxacin-loaded stearic acid solid lipid nanoparticles for ocular delivery: Optimization, in vitro release, ocular tolerance, and antibacterial activity. | 2016 | Int. J. Biol. Macromol. | pmid:26740466 |
Adler C et al. | Molecularly designed lipid microdomains for solid dispersions using a polymer/inorganic carrier matrix produced by hot-melt extrusion. | 2016 | Int J Pharm | pmid:26721729 |
Wood MH et al. | Comparative Adsorption of Saturated and Unsaturated Fatty Acids at the Iron Oxide/Oil Interface. | 2016 | Langmuir | pmid:26707597 |
Bothun GD et al. | Cooperative effects of fatty acids and n-butanol on lipid membrane phase behavior. | 2016 | Colloids Surf B Biointerfaces | pmid:26700234 |
Cárdenas V et al. | Strategy for design NIR calibration sets based on process spectrum and model space: An innovative approach for process analytical technology. | 2015 | J Pharm Biomed Anal | pmid:26001330 |
de Sousa FF et al. | Low-temperature phase transformation studies in the stearic acid: C form. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25909902 |
Bootello MA et al. | Effect of solvents on the fractionation of high oleic-high stearic sunflower oil. | 2015 | Food Chem | pmid:25442612 |
Mohanty B et al. | Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery. | 2015 | Pharm Dev Technol | pmid:24490828 |
Imran M and Nadeem M | Triacylglycerol composition, physico-chemical characteristics and oxidative stability of interesterified canola oil and fully hydrogenated cottonseed oil blends. | 2015 | Lipids Health Dis | pmid:26510410 |
Conde-Sieira M et al. | Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids. | 2015 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:26468264 |
Iwao Y | [Efficient Pharmaceutical Formulation Designs and Their Development Using Mathematical and Statistical Analysis]. | 2015 | Yakugaku Zasshi | pmid:26423868 |
Dong X et al. | [Analysis of meibum by gas chromatography-mass spectrometry]. | 2015 | Zhonghua Yan Ke Za Zhi | pmid:26693651 |