stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Atherosclerosis D050197 85 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperlipidemias D006949 73 associated lipids
Coronary Disease D003327 70 associated lipids
Melanoma D008545 69 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Neuroblastoma D009447 66 associated lipids
Reperfusion Injury D015427 65 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Occupational Diseases D009784 42 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Adenoma D000236 40 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Acne Vulgaris D000152 35 associated lipids
Burns D002056 34 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Hypothyroidism D007037 32 associated lipids
Dermatitis D003872 30 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Insulinoma D007340 28 associated lipids
Breast Neoplasms D001943 24 associated lipids
Cattle Diseases D002418 24 associated lipids
Birth Weight D001724 23 associated lipids
Bacterial Infections D001424 21 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Brain Edema D001929 20 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Ischemia D007511 18 associated lipids
Lymphoma D008223 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Olfaction Disorders D000857 17 associated lipids
Tremor D014202 15 associated lipids
Rosacea D012393 13 associated lipids
Urticaria D014581 13 associated lipids
Otitis Media D010033 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Amnesia D000647 12 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Urethritis D014526 9 associated lipids
Leprosy D007918 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Liver Neoplasms D008113 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Gonorrhea D006069 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Bronchitis D001991 6 associated lipids
Whooping Cough D014917 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Foreign Bodies D005547 5 associated lipids
Syphilis, Latent D013592 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Chancroid D002602 4 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Yaws D015001 4 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Infertility D007246 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Horio T et al. Measurement of flowability of lubricated powders by the vibrating tube method. 2013 Drug Dev Ind Pharm pmid:22781029
Intorre F et al. Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. 2013 Int J Food Sci Nutr pmid:22849318
Wan Q et al. Self-assembled magnetic theranostic nanoparticles for highly sensitive MRI of minicircle DNA delivery. 2013 Nanoscale pmid:23224057
Dhasaiyan P et al. Influence of the sophorolipid molecular geometry on their self-assembled structures. 2013 Chem Asian J pmid:23208802
Baek JS and Cho CW 2-Hydroxypropyl-β-cyclodextrin-modified SLN of paclitaxel for overcoming p-glycoprotein function in multidrug-resistant breast cancer cells. 2013 J. Pharm. Pharmacol. pmid:23215690
Hu P et al. Genotoxicity evaluation of stearic acid grafted chitosan oligosaccharide nanomicelles. 2013 Mutat. Res. pmid:23274307
Salazar J et al. Application of the combinative particle size reduction technology H 42 to produce fast dissolving glibenclamide tablets. 2013 Eur J Pharm Sci pmid:23587645
Fernandes CP et al. Triterpene esters and biological activities from edible fruits of Manilkara subsericea (Mart.) Dubard, Sapotaceae. 2013 Biomed Res Int pmid:23509702
You J et al. Specific tumor delivery of paclitaxel using glycolipid-like polymer micelles containing gold nanospheres. 2013 Biomaterials pmid:23510855
Osorio JG and Muzzio FJ Effects of powder flow properties on capsule filling weight uniformity. 2013 Drug Dev Ind Pharm pmid:23902366
Vadakkan MV et al. Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage. 2013 Int J Nanomedicine pmid:23990716
Asumadu-Mensah A et al. Solid lipid dispersions: potential delivery system for functional ingredients in foods. 2013 J. Food Sci. pmid:23865449
Hagen RM et al. Conjugated linoleate reduces prostate cancer viability whereas the effects of oleate and stearate are cell line-dependent. 2013 Anticancer Res. pmid:24123008
Guo H et al. Self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates for delivery of doxorubicin. 2013 Int J Pharm pmid:24140544
Cvetković Z et al. Distribution of plasma fatty acids is associated with response to chemotherapy in non-Hodgkin's lymphoma patients. 2013 Med. Oncol. pmid:24085546
Pan S et al. Particle formation by supercritical fluid extraction and expansion process. 2013 ScientificWorldJournal pmid:24223031
Li P et al. Effect of non-esterified fatty acids on fatty acid metabolism-related genes in calf hepatocytes cultured in vitro. 2013 Cell. Physiol. Biochem. pmid:24335176
Wahl PR et al. Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion. 2013 Int J Pharm pmid:23911343
Tammaro A et al. Magnesium stearate: an underestimated allergen. 2012 Oct-Dec J. Biol. Regul. Homeost. Agents pmid:23241129
Hentzschel CM et al. Comparison of traditional and novel tableting excipients: physical and compaction properties. 2012 Nov-Dec Pharm Dev Technol pmid:21740091
Khan FN and Dehghan MH Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. 2012 Jan-Mar Sci Pharm pmid:22396916
Pujeri SS et al. Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. 2012 Jan-Mar Sci Pharm pmid:22396908
Aling J and Podczeck F The filling of powdered herbs into two-piece hard capsules using hydrogenated cotton seed oil as lubricant. 2012 Eur J Pharm Sci pmid:22960627
Kottala N et al. Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets. 2012 AAPS PharmSciTech pmid:22965660
Som I et al. Status of surfactants as penetration enhancers in transdermal drug delivery. 2012 J Pharm Bioallied Sci pmid:22368393
Al-Ghamdi AF et al. Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. 2012 Chem Cent J pmid:22353684
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Walash MI et al. Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. 2012 Chem Cent J pmid:22333299
Ghanam RH et al. Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. 2012 Front Microbiol pmid:22363329
Rozema E et al. Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. 2012 Evid Based Complement Alternat Med pmid:22675394
Patel K et al. Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design. 2012 AAPS PharmSciTech pmid:22167415
Jubie S et al. Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. 2012 Eur J Med Chem pmid:22770606
Krogager TP et al. Identification of a potential biomarker panel for the intake of the common dietary trans fat elaidic acid (trans∆9-C18:1). 2012 J Proteomics pmid:22483997
Pawar AA et al. Influence of precursor solvent properties on matrix crystallinity and drug release rates from nanoparticle aerosol lipid matrices. 2012 Int J Pharm pmid:22469694
Zhu S et al. Lysosomal delivery of a lipophilic gemcitabine prodrug using novel acid-sensitive micelles improved its antitumor activity. 2012 Bioconjug. Chem. pmid:22471294
Wajid NA and Halpern BP Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. 2012 Chem. Senses pmid:22459162
Sellami M et al. Enzymatic transesterification of palm stearin and olein blends to produce zero-trans margarine fat. 2012 BMC Biotechnol. pmid:22889174
Li Y et al. New bactericidal surgical suture coating. 2012 Langmuir pmid:22877364
Das SC and Stewart PJ Characterising surface energy of pharmaceutical powders by inverse gas chromatography at finite dilution. 2012 J. Pharm. Pharmacol. pmid:22881445
Yavuz B et al. An overview on dry eye treatment: approaches for cyclosporin a delivery. 2012 ScientificWorldJournal pmid:22619624
Dziewulska A et al. Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle. 2012 Mol. Membr. Biol. pmid:22881371
Zhang WY et al. Chronic unpredictable mild stress affects myocardial metabolic profiling of SD rats. 2012 J Pharm Biomed Anal pmid:22658902
Tuli RA et al. Studies on the effect of the size of polycaprolactone microspheres for the dispersion of salbutamol sulfate from dry powder inhaler formulations. 2012 Pharm. Res. pmid:22584947
Itoh Y and Hasegawa T Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. 2012 J Phys Chem A pmid:22551093
Dobrzyn P et al. Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation. 2012 Mitochondrion pmid:21664496
Guo C et al. In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. 2012 J Nanosci Nanotechnol pmid:22523972
Bevilacqua A et al. Selection of Yeasts as Starter Cultures for Table Olives: A Step-by-Step Procedure. 2012 Front Microbiol pmid:22666220
Shah KU and Khan GM Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. 2012 ScientificWorldJournal pmid:22649325
Polizzotti BD et al. Intrapericardial delivery of gelfoam enables the targeted delivery of Periostin peptide after myocardial infarction by inducing fibrin clot formation. 2012 PLoS ONE pmid:22590609
Song IS et al. Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. 2012 PLoS ONE pmid:22590580