stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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KORN ED | BIOSYNTHESIS OF UNSATURATED FATTY ACIDS IN ACANTHAMOEBA SP. | 1964 | J. Biol. Chem. | pmid:14169137 |
SAMBASIVARAO K and MCCLUER RH | LIPID COMPONENTS OF GANGLIOSIDES. | 1964 | J. Lipid Res. | pmid:14173314 |
ENG LF et al. | SEPARATION AND ISOLATION OF METHYL ESTERS AND DIMETHYLACETALS FORMED FROM BRAIN LIPIDS. | 1964 | J. Lipid Res. | pmid:14173320 |
PASCAUD M | [THE PHOSPHOLIPIDS OF THE HEPATIC CELL. FUNCTIONAL INTERPRETATION OF THEIR RENEWAL. I. NATURE. SPECIFICITY OF THEIR CONSTITUTIVE FATTY ACIDS]. | 1964 | Biochim. Biophys. Acta | pmid:14250490 |
DOBIASOVA M et al. | FATTY ACID COMPOSITION IN DEVELOPING RATS. FATTY ACID COMPOSITION OF TRIGLYCERIDES AND PHOSPHOLIPIDS IN SOME ORGANS OF THE RAT DURING POSTNATAL DEVELOPMENT. | 1964 | Biochim. Biophys. Acta | pmid:14250492 |
WILLEBRANDS AF | UTILIZATION OF INDIVIDUAL NON-ESTERIFIED FATTY ACIDS BY THE ISOLATED PERFUSED RAT HEART. | 1964 | Biochim. Biophys. Acta | pmid:14250498 |
FARSTAD M | DETERMINATION OF FATTY ACIDS IN CEREBROSPINAL FLUID. II. QUALITATIVE AND QUANTITATIVE STUDIES BY A COMBINATION OF ALKALI TITRATION AND GAS CHROMATOGRAPHY. | 1964 | Scand. J. Clin. Lab. Invest. | pmid:14161847 |
MISRA UK and TURNER DA | FATTY ACID COMPOSITION OF PHOSPHATIDYL ETHANOLAMINE SERINE FROM DOG BILE. | 1964 | Can. J. Biochem. | pmid:14164275 |
LYMAN RL et al. | EFFECT OF ESTRADIOL AND TESTOSTERONE ON THE FATTY ACIDS OF PLASMA CHOLESTERYL ESTERS AND PHOSPHOLIPIDS IN THE CASTRATED RAT. | 1964 | Can. J. Biochem. | pmid:14164283 |
KUKSIS A | GAS CHROMATOGRAPHIC FRACTIONATION OF NATURAL STERYL ESTER MIXTURES. | 1964 | Can. J. Biochem. | pmid:14164287 |