stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Weight Gain D015430 101 associated lipids
Insulin Resistance D007333 99 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Atherosclerosis D050197 85 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Alzheimer Disease D000544 76 associated lipids
Hyperlipidemias D006949 73 associated lipids
Coronary Disease D003327 70 associated lipids
Melanoma D008545 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Muselík J et al. Influence of process parameters on content uniformity of a low dose active pharmaceutical ingredient in a tablet formulation according to GMP. 2014 Acta Pharm pmid:25296681
Rico JE et al. Compared with stearic acid, palmitic acid increased the yield of milk fat and improved feed efficiency across production level of cows. 2014 J. Dairy Sci. pmid:24342689
Liau CP et al. Preparation and characterization of polyhydroxybutyrate/polycaprolactone nanocomposites. 2014 ScientificWorldJournal pmid:24600329
Woo JO et al. Development of a controlled release of salicylic acid loaded stearic acid-oleic acid nanoparticles in cream for topical delivery. 2014 ScientificWorldJournal pmid:24578624
Dou J et al. Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration. 2014 Colloids Surf B Biointerfaces pmid:24157590
Meulenaar J et al. Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling. 2014 J Pharm Sci pmid:24311366
Muzíková J et al. A study of micronized poloxamers as lubricants in direct compression of tablets. 2013 Nov-Dec Acta Pol Pharm pmid:24383332
Aljaberi A et al. Understanding and optimizing the dual excipient functionality of sodium lauryl sulfate in tablet formulation of poorly water soluble drug: wetting and lubrication. 2013 Mar-Apr Pharm Dev Technol pmid:23009028
Kushner J Utilizing quantitative certificate of analysis data to assess the amount of excipient lot-to-lot variability sampled during drug product development. 2013 Mar-Apr Pharm Dev Technol pmid:21877870
Hussain T et al. Effect of two hydrophobic polymers on the release of gliclazide from their matrix tablets. 2013 Jul-Aug Acta Pol Pharm pmid:23923399
Muzíková J and Sináglová P Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses. 2013 Jan-Feb Acta Pol Pharm pmid:23610968
Dawes J et al. Application of external lubrication during the roller compaction of adhesive pharmaceutical formulations. 2013 Pharm Dev Technol pmid:22813432
Stanisz B et al. Effect of pharmaceutical excipients on the stability of angiotensin-converting enzyme inhibitors in their solid dosage formulations. 2013 Drug Dev Ind Pharm pmid:22348774
Mazel V et al. The surface layer of pharmaceutical compacts: the role of the punch surface and its impact on the mechanical properties of the compacts. 2013 Int J Pharm pmid:22902389
Intorre F et al. Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. 2013 Int J Food Sci Nutr pmid:22849318
Franc A et al. [Content uniformity of warfarin-containing mixtures and tablets]. 2013 Ceska Slov Farm pmid:24047147
Li L et al. Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. 2013 Int J Pharm pmid:23624081
Mužíková J and Sináglová P A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose. 2013 Ceska Slov Farm pmid:23961814
Neutsch L et al. UPEC biomimickry at the urothelial barrier: lectin-functionalized PLGA microparticles for improved intravesical chemotherapy. 2013 Int J Pharm pmid:23628404
Emken E Human studies using isotope labeled fatty acids: answered and unanswered questions. 2013 J Oleo Sci pmid:23648399
Dangarembizi R et al. Aloe ferox seed: a potential source of oil for cosmetic and pharmaceutical use. 2013 Nat Prod Commun pmid:23678824
Maia M et al. A novel, direct, reagent-free method for the detection of beeswax adulteration by single-reflection attenuated total reflectance mid-infrared spectroscopy. 2013 Talanta pmid:23598195
Li CC et al. [In situ rat intestine absorption of paclitaxel-loaded solid lipid nanoparticles modified with cell-penetrating peptides]. 2013 Yao Xue Xue Bao pmid:23600154
Salehi M et al. Debinding mechanisms in thermoplastic processing of a Ba(0.5)Sr(0.5)Co(0.8)Fe(0.2)O(3-δ)- stearic acid-polystyrene mixture. 2013 ChemSusChem pmid:23281298
He M et al. Controllable stearic acid crystal induced high hydrophobicity on cellulose film surface. 2013 ACS Appl Mater Interfaces pmid:23289586
Wan Q et al. Self-assembled magnetic theranostic nanoparticles for highly sensitive MRI of minicircle DNA delivery. 2013 Nanoscale pmid:23224057
Zhou X et al. The effect of saturated fatty acids on methanogenesis and cell viability of Methanobrevibacter ruminantium. 2013 Archaea pmid:23710130
Silberstein T et al. Saturated fatty acid composition of human milk in Israel: a comparison between Jewish and Bedouin women. 2013 Isr. Med. Assoc. J. pmid:23781748
Azordegan N et al. Carcinogenesis alters fatty acid profile in breast tissue. 2013 Mol. Cell. Biochem. pmid:23180247
Delbecq F et al. N-stearoyl amino acid derivatives: potent biomimetic hydro/organogelators as templates for preparation of gold nanoparticles. 2013 J Colloid Interface Sci pmid:23089597
Chen JJ et al. New pterosin sesquiterpenes and antitubercular constituents from Pteris ensiformis. 2013 Chem. Biodivers. pmid:24130033
Avalle P et al. Interrogating erosion-based drug liberation phenomena from hydrophilic matrices using near infrared (NIR) spectroscopy. 2013 Eur J Pharm Sci pmid:23059372
Desai SS et al. Methods for reduction of cohesive forces between carrier and drug in DPI formulation. 2013 Drug Dev Ind Pharm pmid:23050727
Vijayaraghavan M et al. Suitability of polymer materials for production of pulmonary microparticles using a PGSS supercritical fluid technique: preparation of microparticles using PEG, fatty acids and physical or chemicals blends of PEG and fatty acids. 2013 Int J Pharm pmid:23178217
Sharma P et al. Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. 2013 Arch. Biochem. Biophys. pmid:23149273
Jaumot J et al. Blending process modeling and control by multivariate curve resolution. 2013 Talanta pmid:24209372
Uchimoto T et al. Determination of useful ranges of mixing conditions for glycerin Fatty Acid ester by multiple regression analysis. 2013 Chem. Pharm. Bull. pmid:24189302
Tsuchiya A et al. Stearic acid serves as a potent inhibitor of protein tyrosine phosphatase 1B. 2013 Cell. Physiol. Biochem. pmid:24296476
Camacho-Chab JC et al. Emulsifying activity and stability of a non-toxic bioemulsifier synthesized by Microbacterium sp. MC3B-10. 2013 Int J Mol Sci pmid:24065097
Šašiċ S et al. Raman chemical mapping of magnesium stearate delivered by a punch-face lubrication system on the surface of placebo and active tablets. 2013 Appl Spectrosc pmid:24067639
Mérian J et al. Synthetic lipid nanoparticles targeting steroid organs. 2013 J. Nucl. Med. pmid:24071507
Liu Z et al. Changes in the electron paramagnetic resonance spectra of albumin-associated spin-labeled stearic acid as a diagnostic parameter of colorectal cancer. 2013 World J Surg Oncol pmid:24025321
Osorio JG and Muzzio FJ Effects of powder flow properties on capsule filling weight uniformity. 2013 Drug Dev Ind Pharm pmid:23902366
Vadakkan MV et al. Dry powder cationic lipopolymeric nanomicelle inhalation for targeted delivery of antitubercular drug to alveolar macrophage. 2013 Int J Nanomedicine pmid:23990716
Asumadu-Mensah A et al. Solid lipid dispersions: potential delivery system for functional ingredients in foods. 2013 J. Food Sci. pmid:23865449
Høstmark AT et al. Increased serum triglycerides and reduced HDL cholesterol in male rats after intake of ammonium chloride for 3 weeks. 2013 Lipids Health Dis pmid:23800210
Pethrick RA and Song M Dielectric studies of amylose, amylopectin and amylose-stearic acid complexes. 2013 Carbohydr Polym pmid:23399185
Yuan B et al. Laboratory-scale column study for remediation of TCE-contaminated aquifers using three-section controlled-release potassium permanganate barriers. 2013 J Environ Sci (China) pmid:24218827
Pan S et al. Particle formation by supercritical fluid extraction and expansion process. 2013 ScientificWorldJournal pmid:24223031
Subbaramaiah K et al. Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice. 2013 Cancer Prev Res (Phila) pmid:23880231