| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Boutonneuse Fever | D001907 | 5 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchitis | D001991 | 6 associated lipids |
| Burns | D002056 | 34 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rosenthal MD and Whitehurst MC | Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. | 1983 | Biochim. Biophys. Acta | pmid:6615875 |
| Chen H et al. | Effect of cholesterol on miscibility and phase behavior in binary mixtures with synthetic ceramide 2 and octadecanoic acid. Infrared studies. | 2001 | Biochim. Biophys. Acta | pmid:11406112 |
| Bieri VG and Wallach DF | Variations of lipid-protein interactions in erythrocyte ghosts as a function of temperature and pH in physiological and non-physiological ranges. A study using a paramagnetic quenching of protein fluorescence by nitroxide lipid analogues. | 1975 | Biochim. Biophys. Acta | pmid:241415 |
| Zoeller RA and Wood R | The importance of the stearoyl-CoA desaturase system in octadecenoate metabolism in the Morris hepatoma 7288C. | 1985 | Biochim. Biophys. Acta | pmid:2860925 |
| STEIN O and STEIN Y | METABOLISM OF FATTY ACIDS IN THE ISOLATED PERFUSED RAT HEART. | 1963 | Biochim. Biophys. Acta | pmid:14085937 |
| Morrow MR et al. | Glycosphingolipid acyl chain order profiles: substituent effects. | 1995 | Biochim. Biophys. Acta | pmid:7756331 |
| Swendsen CL et al. | Human neutrophils incorporate arachidonic acid and saturated fatty acids into separate molecular species of phospholipids. | 1987 | Biochim. Biophys. Acta | pmid:3105590 |
| Riordan JR et al. | Plasma membrane lipids of human diploid fibroblasts from normal individuals and patients with cystic fibrosis. | 1979 | Biochim. Biophys. Acta | pmid:476136 |
| Eliasz AW et al. | Phospholipid phase transitions. Effects of n-alcohols, n-monocarboxylic acids, phenylalkyl alcohols and quaternary ammonium compounds. | 1976 | Biochim. Biophys. Acta | pmid:971432 |
| Kogure K et al. | Effect of dicetylphosphate or stearic acid on spontaneous transfer of protein from influenza virus-infected cells to dimyristoylphosphatidylcholine liposomes. | 1997 | Biochim. Biophys. Acta | pmid:9370255 |
| Woldseth B et al. | Incorporation of stearic acid (18:0) and palmitic acid (16:0) in phospholipid molecular species studied in isolated rat liver cells. | 1993 | Biochim. Biophys. Acta | pmid:8481391 |
| Watanabe S and Sato T | Effects of free fatty acids on the binding of bovine and human serum albumin with steroid hormones. | 1996 | Biochim. Biophys. Acta | pmid:8620023 |
| Sparks JD et al. | Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells. | 1997 | Biochim. Biophys. Acta | pmid:9233686 |
| Streichman S et al. | Unique profile for erythrocyte membrane acetylcholinesterase in hereditary spherocytosis. | 1983 | Biochim. Biophys. Acta | pmid:6849970 |
| Beaumelle BD and Vial HJ | Modification of the fatty acid composition of individual phospholipids and neutral lipids after infection of the simian erythrocyte by Plasmodium knowlesi. | 1986 | Biochim. Biophys. Acta | pmid:3719005 |
| ELOVSON J | METABOLISM OF SOME MONOHYDROXYSTEARIC ACIDS IN THE INTACT RAT. | 1964 | Biochim. Biophys. Acta | pmid:14194233 |
| Arukuusk P et al. | New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids. | 2013 | Biochim. Biophys. Acta | pmid:23357356 |
| DAVIDOFF FF | THE METABOLISM OF 9(10)-HYDROXYSTEARIC ACID BY THE CELLULAR SLIME MOLD, DICTYOSTELIUM DISCOIDEUM. | 1964 | Biochim. Biophys. Acta | pmid:14220732 |
| Holub BJ | The relative deacylation of different molecular species of endogenous phosphatidylethanolamine in rat liver microsomes by phospholipase activity. | 1982 | Biochim. Biophys. Acta | pmid:7093298 |
| MENZEL DB and OLCOTT HS | POSITIONAL DISTRIBUTION OF FATTY ACIDS IN FISH AND OTHER ANIMAL LECITHINS. | 1964 | Biochim. Biophys. Acta | pmid:14181289 |
| DAY AJ et al. | THE INCORPORATION OF 14-C-LABELLED ACETATE INTO LONG CHAIN FATTY ACIDS BY MACROPHAGES IN VITRO. | 1964 | Biochim. Biophys. Acta | pmid:14181291 |
| GELLHORN A and BENJAMIN W | THE INTRACELLULAR LOCALIZATION OF AN ENZYMATIC DEFECT OF LIPID METABOLISM IN DIABETIC RATS. | 1964 | Biochim. Biophys. Acta | pmid:14181293 |
| IKAWA M | OCCURRENCE AND IDENTIFICATION OF CIS-VACCENIC ACID IN LEUCONOSTOC MESENTEROIDES. | 1964 | Biochim. Biophys. Acta | pmid:14181302 |
| Slomiany BL et al. | Mucus glycoprotein of human saliva: differences in the associated and covalently bound lipids with caries. | 1986 | Biochim. Biophys. Acta | pmid:3518803 |
| BURTON RM and GIBBONS JM | LIPID COMPOSITION OF A RAT-BRAIN SYNAPTIC-VESICLE FRACTION. | 1964 | Biochim. Biophys. Acta | pmid:14181307 |
| Morgan H et al. | Proton transport at the monolayer-water interface. | 1991 | Biochim. Biophys. Acta | pmid:1848448 |
| Streichman S et al. | EPR study of the hydrophobic interaction of spectrin with fatty acids. | 1991 | Biochim. Biophys. Acta | pmid:1648396 |
| Møller JK et al. | Effect of nitrosylmyoglobin and saturated fatty acid anions on metmyoglobin-catalyzed oxidation of aqueous methyl linoleate emulsions. | 2002 | Biochim. Biophys. Acta | pmid:11985897 |
| Chien JL and Hogan EL | Characterization of two gangliosides of the paragloboside series from chicken skeletal muscle. | 1980 | Biochim. Biophys. Acta | pmid:7236652 |
| Holub BJ | The suitability of different acyl acceptors as substrates for the acyl-Coa : 2-acyl-sn-glycero-3-phosphorylcholine acyltransferase in rat liver microsomes. | 1981 | Biochim. Biophys. Acta | pmid:7248321 |
| PASCAUD M | [THE PHOSPHOLIPIDS OF THE HEPATIC CELL. FUNCTIONAL INTERPRETATION OF THEIR RENEWAL. I. NATURE. SPECIFICITY OF THEIR CONSTITUTIVE FATTY ACIDS]. | 1964 | Biochim. Biophys. Acta | pmid:14250490 |
| DOBIASOVA M et al. | FATTY ACID COMPOSITION IN DEVELOPING RATS. FATTY ACID COMPOSITION OF TRIGLYCERIDES AND PHOSPHOLIPIDS IN SOME ORGANS OF THE RAT DURING POSTNATAL DEVELOPMENT. | 1964 | Biochim. Biophys. Acta | pmid:14250492 |
| WILLEBRANDS AF | UTILIZATION OF INDIVIDUAL NON-ESTERIFIED FATTY ACIDS BY THE ISOLATED PERFUSED RAT HEART. | 1964 | Biochim. Biophys. Acta | pmid:14250498 |
| Yoshida S et al. | Effect of phospholipase A2 and free fatty acids on lipid-protein interactions in long- and very-long-chain fatty acyl-CoA elongation enzyme systems of brain microsomes. | 1989 | Biochim. Biophys. Acta | pmid:2502180 |
| Baker RR and Chang HY | A comparison of lysophosphatidylcholine acyltransferase activities in neuronal nuclei and microsomes isolated from immature rabbit cerebral cortex. | 1981 | Biochim. Biophys. Acta | pmid:7306562 |
| Wang Y et al. | Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. | 2017 | Biochim. Biophys. Acta | pmid:28526351 |
| George M and Chepenik KP | Phospholipase A activities in embryonic palate mesenchyme cells in vitro. | 1985 | Biochim. Biophys. Acta | pmid:3927980 |
| SHAFRIR E et al. | PARTITION OF FATTY ACIDS OF 20-24 CARBON ATOMS BETWEEN SERUM ALBUMIN AND LIPOPROTEINS. | 1965 | Biochim. Biophys. Acta | pmid:14320230 |
| ELOVSON J | CHAIN-SHORTENING OF STEARIC ACID IN THE INTACT RAT. | 1965 | Biochim. Biophys. Acta | pmid:14290835 |
| MCCARTHY RD et al. | THE CONVERSION OF STEARIC ACID TO OLEIC IN FRESHLY SECRETED MILK. | 1965 | Biochim. Biophys. Acta | pmid:14292868 |
| Malmberg P et al. | Localization of lipids in the aortic wall with imaging TOF-SIMS. | 2007 | Biochim. Biophys. Acta | pmid:17240191 |
| Haeffner EW and Friedel R | Induction of an endothermic transition in the Arrhenius plot of fatty acid uptake by lipid-depleted ascites tumor cells. | 1989 | Biochim. Biophys. Acta | pmid:2775760 |
| Ellingson JS and Seenaiah B | The selective use of stearoyl-polyunsaturated molecular species of phosphatidylcholine and phosphatidylethanolamine for the synthesis of phosphatidylserine. | 1994 | Biochim. Biophys. Acta | pmid:8011673 |
| Lagrost L | Differential effects of cis and trans fatty acid isomers, oleic and elaidic acids, on the cholesteryl ester transfer protein activity. | 1992 | Biochim. Biophys. Acta | pmid:1543738 |
| Mortimer BC et al. | The effect of added monoacylglycerols on the removal from plasma of chylomicron-like emulsions injected intravenously in rats. | 1989 | Biochim. Biophys. Acta | pmid:2713386 |
| Golovina EA and Tikhonov AN | The structural differences between the embryos of viable and nonviable wheat seeds as studied with the EPR spectroscopy of lipid-soluble spin labels. | 1994 | Biochim. Biophys. Acta | pmid:8142440 |
| Yoshida S and Takeshita M | Arachidoyl- and arachidonoyl-CoA elongation mechanism in swine cerebral microsomes. | 1984 | Biochim. Biophys. Acta | pmid:6466693 |
| Miller RW and De La Roche IA | Properties of spin labelled membranes of Fusarium oxysporum f. sp. lycopersici. | 1976 | Biochim. Biophys. Acta | pmid:182261 |
| Ruf HH and Gratzl M | Binding of nitroxide stearate spin labels to bovine serum albumin. | 1976 | Biochim. Biophys. Acta | pmid:184832 |
| Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |