stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Bacterial Infections D001424 21 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Brain Edema D001929 20 associated lipids
Breast Neoplasms D001943 24 associated lipids
Bronchitis D001991 6 associated lipids
Burns D002056 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Zhang X et al. Effect of Chemicals on Morphology and Luminescence of CdSe Quantum Dots. 2015 J Nanosci Nanotechnol pmid:26353513
Bhattacharya S et al. Increasing the stearate content in seed oil of Brassica juncea by heterologous expression of MlFatB affects lipid content and germination frequency of transgenic seeds. 2015 Plant Physiol. Biochem. pmid:26351151
Seethamraju S et al. Reactive interlayer based ultra-low moisture permeable membranes for organic photovoltaic encapsulation. 2015 Phys Chem Chem Phys pmid:26278515
Yang W et al. Facile Synthesis of Gd-Cu-In-S/ZnS Bimodal Quantum Dots with Optimized Properties for Tumor Targeted Fluorescence/MR In Vivo Imaging. 2015 ACS Appl Mater Interfaces pmid:26257133
Zhong T et al. Effects of ultrasound treatment on lipid self-association and properties of methylcellulose/stearic acid blending films. 2015 Carbohydr Polym pmid:26256202
He H et al. VB12-coated Gel-Core-SLN containing insulin: Another way to improve oral absorption. 2015 Int J Pharm pmid:26253378
Xu W et al. Bilayers at High pH in the Fatty Acid Soap Systems and the Applications for the Formation of Foams and Emulsions. 2015 J Phys Chem B pmid:26237503
Hoffmann M et al. Investigation into process-induced de-aggregation of cohesive micronised API particles. 2015 Int J Pharm pmid:26235919
Gong X et al. Dependence of tablet brittleness on tensile strength and porosity. 2015 Int J Pharm pmid:26226338
Liu G et al. Cell membrane-inspired polymeric micelles as carriers for drug delivery. 2015 Biomater Sci pmid:26222292
Qu L et al. Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders. 2015 Eur J Pharm Sci pmid:26215464
Hong J et al. Effects of genetic variants for the swine FABP3, HMGA1, MC4R, IGF2, and FABP4 genes on fatty acid composition. 2015 Meat Sci. pmid:26172243
Park JH et al. Development of DH-I-180-3 loaded lipid nanoparticle for photodynamic therapy. 2015 Int J Pharm pmid:26149935
de Paiva EJ et al. Influence of two different alcohols in the esterification of fatty acids over layered zinc stearate/palmitate. 2015 Bioresour. Technol. pmid:26143001
Ricci M et al. Growth and Dissolution of Calcite in the Presence of Adsorbed Stearic Acid. 2015 Langmuir pmid:26087312
Santos IC et al. Paired-ion electrospray ionization--triple quadrupole tandem mass spectrometry for quantification of anionic surfactants in waters. 2015 Talanta pmid:26078166
Rizzuti B et al. Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation. 2015 Arch. Biochem. Biophys. pmid:26048999
Cárdenas V et al. Strategy for design NIR calibration sets based on process spectrum and model space: An innovative approach for process analytical technology. 2015 J Pharm Biomed Anal pmid:26001330
Kerth CR et al. Consumer sensory evaluation, fatty acid composition, and shelf-life of ground beef with subcutaneous fat trimmings from different carcass locations. 2015 Meat Sci. pmid:25688688
Tai Z et al. Biodegradable stearylated peptide with internal disulfide bonds for efficient delivery of siRNA in vitro and in vivo. 2015 Biomacromolecules pmid:25686200
Thakkar A et al. Evaluation of ibuprofen loaded solid lipid nanoparticles and its combination regimens for pancreatic cancer chemoprevention. 2015 Int. J. Oncol. pmid:25652350
Sagiri SS et al. Stearic acid based oleogels: a study on the molecular, thermal and mechanical properties. 2015 Mater Sci Eng C Mater Biol Appl pmid:25579972
Rana S et al. A spatio-temporal cardiomyocyte targeted vector system for efficient delivery of therapeutic payloads to regress cardiac hypertrophy abating bystander effect. 2015 J Control Release pmid:25575863
Wei X et al. Structure and properties of moisture-resistant konjac glucomannan films coated with shellac/stearic acid coating. 2015 Carbohydr Polym pmid:25542116
Zeng Q et al. Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses. 2015 J Control Release pmid:25540903
Piantoni P et al. Milk production responses to dietary stearic acid vary by production level in dairy cattle. 2015 J. Dairy Sci. pmid:25529423
Vercruysse J et al. Use of a continuous twin screw granulation and drying system during formulation development and process optimization. 2015 Eur J Pharm Biopharm pmid:25528462
Schrank S et al. The effect of the drying temperature on the properties of wet-extruded calcium stearate pellets: pellet microstructure, drug distribution, solid state and drug dissolution. 2015 Int J Pharm pmid:25526671
Foraita S et al. Impact of the oxygen defects and the hydrogen concentration on the surface of tetragonal and monoclinic ZrO2 on the reduction rates of stearic acid on Ni/ZrO2. 2015 Chemistry pmid:25504844
Yan S et al. Autoxidated linolenic acid inhibits aflatoxin biosynthesis in Aspergillus flavus via oxylipin species. 2015 Fungal Genet. Biol. pmid:25498164
Yang Y et al. Ligand-directed stearic acid grafted chitosan micelles to increase therapeutic efficacy in hepatic cancer. 2015 Mol. Pharm. pmid:25495890
Yi HX et al. Effect of anionic PEGylated polypeptide on gene transfection mediated by glycolipid conjugate micelles. 2015 Mol. Pharm. pmid:25490413
Leonardi A et al. Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit. 2015 Int J Pharm pmid:25448580
Bootello MA et al. Effect of solvents on the fractionation of high oleic-high stearic sunflower oil. 2015 Food Chem pmid:25442612
Cantor SL et al. Development and optimization of taste-masked orally disintegrating tablets (ODTs) of clindamycin hydrochloride. 2015 Drug Dev Ind Pharm pmid:25000481
Qu L et al. Investigation of the potential for direct compaction of a fine ibuprofen powder dry-coated with magnesium stearate. 2015 Drug Dev Ind Pharm pmid:24738790
Momoh MA et al. Influence of magnesium stearate on the physicochemical and pharmacodynamic characteristics of insulin-loaded Eudragit entrapped mucoadhesive microspheres. 2015 Drug Deliv pmid:24670092
Doignon F et al. Requirement of Phosphoinositides Containing Stearic Acid To Control Cell Polarity. 2015 Mol. Cell. Biol. pmid:26711260
Miyazaki Y et al. Dry Powder Coating using Planetary Centrifugal Mixer. 2015 J Pharm Pharm Sci pmid:26517137
Imran M and Nadeem M Triacylglycerol composition, physico-chemical characteristics and oxidative stability of interesterified canola oil and fully hydrogenated cottonseed oil blends. 2015 Lipids Health Dis pmid:26510410
Conde-Sieira M et al. Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids. 2015 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:26468264
Rehman M et al. Solid and liquid lipid-based binary solid lipid nanoparticles of diacerein: in vitro evaluation of sustained release, simultaneous loading of gold nanoparticles, and potential thermoresponsive behavior. 2015 Int J Nanomedicine pmid:25897224
Harding SV et al. Desaturation index versus isotopically measured de novo lipogenesis as an indicator of acute systemic lipogenesis. 2015 BMC Res Notes pmid:25879456
Silva-Neta IC et al. Expression of genes related to tolerance to low temperature for maize seed germination. 2015 Genet. Mol. Res. pmid:25867416
Jung SW et al. Mechanism of antibacterial activity of liposomal linolenic acid against Helicobacter pylori. 2015 PLoS ONE pmid:25793403
Othman AR et al. Elucidation of in-vitro anti-inflammatory bioactive compounds isolated from Jatropha curcas L. plant root. 2015 BMC Complement Altern Med pmid:25652309
Aardema H et al. Free fatty acid levels in fluid of dominant follicles at the preferred insemination time in dairy cows are not affected by early postpartum fatty acid stress. 2015 J. Dairy Sci. pmid:25648816
Ma W et al. Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study. 2015 Am. J. Clin. Nutr. pmid:25527759
Veselỳ M et al. Photocatalytic and Antimicrobial Activity of Printed Hybrid Titania/Silica Layers. 2015 J Nanosci Nanotechnol pmid:26716211
Dong X et al. [Analysis of meibum by gas chromatography-mass spectrometry]. 2015 Zhonghua Yan Ke Za Zhi pmid:26693651