stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Bacterial Infections D001424 21 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Brain Edema D001929 20 associated lipids
Breast Neoplasms D001943 24 associated lipids
Bronchitis D001991 6 associated lipids
Burns D002056 34 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Balducci AG et al. Layered lipid microcapsules for mesalazine delayed-release in children. 2011 Int J Pharm pmid:22001795
Kumar RV and Sinha VR Tailoring of drug delivery of 5-fluorouracil to the colon via a mixed film coated unit system. 2011 Acta Pharm pmid:21945913
Wang S et al. Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. 2011 PLoS Pathog. pmid:21731492
Paczkowski S and Schütz S Post-mortem volatiles of vertebrate tissue. 2011 Appl. Microbiol. Biotechnol. pmid:21720824
Haghjou N et al. Sustained release intraocular drug delivery devices for treatment of uveitis. 2011 J Ophthalmic Vis Res pmid:22454753
Hisazumi J et al. Quantification of pharmaceutical polymorphs and prediction of dissolution rate using theophylline tablet by terahertz spectroscopy. 2011 Chem. Pharm. Bull. pmid:21467671
Guntupalli R et al. Phage Langmuir monolayers and Langmuir-Blodgett films. 2011 Colloids Surf B Biointerfaces pmid:20843668
Ash MM et al. Phytosterol stearate esters elicit similar responses on plasma lipids and cholesterol absorption but different responses on fecal neutral sterol excretion and hepatic free cholesterol in male Syrian hamsters. 2011 Nutr Res pmid:21840470
Saeed M et al. Assessment of diffuse transmission and reflection modes in near-infrared quantification, part 2: DIFFuse reflection information depth. 2011 J Pharm Sci pmid:20862671
Uchino T et al. Effects of coating materials and size of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane. 2011 J Toxicol Sci pmid:21297346
Shin S et al. Time-oriented experimental design method to optimize hydrophilic matrix formulations with gelation kinetics and drug release profiles. 2011 Int J Pharm pmid:21251963
Jishnu V et al. Formulation and evaluation of cephalexin extended release matrix tablets using 3 factorial design. 2011 J Young Pharm pmid:22224031
Wang K et al. Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. 2011 Int J Nanomedicine pmid:22238509
Du YZ et al. Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles. 2011 Int J Nanomedicine pmid:21845046
Oosterveer MH et al. Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. 2011 Nutr Metab (Lond) pmid:22201701
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Wu DJ et al. Metabonomics-based omics study and atherosclerosis. 2011 J Clin Bioinforma pmid:22040517
Walash MI et al. Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids. 2011 Chem Cent J pmid:21996025
El-Enany NM et al. Spectrofluorimetric determination of sertraline in dosage forms and human plasma through derivatization with 9-fluorenylmethyl chloroformate. 2011 Chem Cent J pmid:21978386
Tachibana H Green tea polyphenol sensing. 2011 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:21422740
Zenita O and Basavaiah K Utility of N-bromosuccinimide for the titrimetric and spectrophotometric determination of famotidine in pharmaceutical formulations. 2011 Int J Anal Chem pmid:21760785
Almer G et al. Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. 2011 Int J Nanomedicine pmid:21753879
Brown JD et al. VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. 2011 PLoS ONE pmid:21750705
Fernandez C et al. Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. 2011 PLoS ONE pmid:21738729
Singhal A et al. Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability. 2011 Pharmacognosy Res pmid:21731393
Amaya KR et al. Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry. 2011 J. Neurochem. pmid:21496023
Duangjit S et al. Characterization and In Vitro Skin Permeation of Meloxicam-Loaded Liposomes versus Transfersomes. 2011 J Drug Deliv pmid:21490750
Kumaravelrajan R et al. Development and evaluation of controlled porosity osmotic pump for nifedipine and metoprolol combination. 2011 Lipids Health Dis pmid:21477386
Kordyukova LV et al. Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. 2011 Biochim. Biophys. Acta pmid:21420932
Gande S and Rao Y Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers. 2011 Daru pmid:22615658
Varshosaz J et al. Development of novel budesonide pellets based on CODES(TM) technology: In vitro/in vivo evaluation in induced colitis in rats. 2011 Daru pmid:22615647
Dey S et al. Formulation and optimization of sustained release Stavudine microspheres using response surface methodology. 2011 ISRN Pharm pmid:22389855
Prajapati ST et al. Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. 2011 ISRN Pharm pmid:22389845
Kulinowski P et al. Magnetic resonance imaging and image analysis for assessment of HPMC matrix tablets structural evolution in USP Apparatus 4. 2011 Pharm. Res. pmid:21181545
Mantzaris MD et al. Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells. 2011 FEBS J. pmid:21182590
González-Mira E et al. Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen. 2011 J Pharm Sci pmid:20575052
Wang GG et al. Self-assembled biomimetic superhydrophobic CaCO3 coating inspired from fouling mineralization in geothermal water. 2011 Langmuir pmid:21919516
Basu BJ and Manasa J Effect of deposition parameters on the wettability and microstructure of superhydrophobic films with hierarchical micro-nano structures. 2011 J Colloid Interface Sci pmid:21864844
Liu X et al. Synthesis of high quality and stability CdS quantum dots with overlapped nucleation-growth process in large scale. 2011 J Colloid Interface Sci pmid:21040929
Tamilvanan S et al. In vitro and in vivo evaluation of hydrophilic and hydrophobic polymers-based nicorandil-loaded peroral tablet compared with its once-daily commercial sustained-release tablet. 2011 Drug Dev Ind Pharm pmid:20923389
Aardema H et al. Oleic acid prevents detrimental effects of saturated fatty acids on bovine oocyte developmental competence. 2011 Biol. Reprod. pmid:21311036
Pingali K et al. Mixing order of glidant and lubricant--influence on powder and tablet properties. 2011 Int J Pharm pmid:21356286
Zaki Rizkalla CM et al. In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery. 2011 AAPS PharmSciTech pmid:21800216
Gremos S et al. Direct enzymatic acylation of cellulose pretreated in BMIMCl ionic liquid. 2011 Bioresour. Technol. pmid:20888759
Yu DG et al. Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles. 2011 Chem. Commun. (Camb.) pmid:21107459
Das SC et al. Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate. 2011 Eur J Pharm Sci pmid:21621612
Laverroux S et al. Isomerization of vaccenic acid to cis and trans C18:1 isomers during biohydrogenation by rumen microbes. 2011 Lipids pmid:21706384
Someshwar K et al. Formulation and evaluation of effervescent floating tablets of tizanidine hydrochloride. 2011 Acta Pharm pmid:21684848
Sekharan TR et al. Formulation and Evaluation of Hydroxypropyl Methylcellulose-based Controlled Release Matrix Tablets for Theophylline. 2011 Indian J Pharm Sci pmid:22707833
Pani NR et al. Compatibility studies of nateglinide with excipients in immediate release tablets. 2011 Acta Pharm pmid:21684850
Nagarsekar KS et al. Antioxidant and antilipid peroxidation potential of supercritical fluid extract and ethanol extract of leaves of vitex negundo linn. 2011 Indian J Pharm Sci pmid:22707827
Masareddy R et al. Development of Orodispersible Tizanidine HCl Tablets Using Spray Dried Coprocessed Exipient Bases. 2011 Indian J Pharm Sci pmid:22707822
Lan DM et al. A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. 2011 Int J Mol Sci pmid:21747717
Chaturvedi K et al. Floating matrix dosage form for propranolol hydrochloride based on gas formation technique: development and in vitro evaluation. 2010 Oct-Dec Sci Pharm pmid:21179326
Terekhova EA et al. [Stearic acid methyl ether: a new extracellular metabolite of the obligate methylotrophic bacterium Methylophilus quaylei]. 2010 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:20391761
Kristó K et al. Effect of lubricant on spreading of coating liquid on surface of tablets containing pancreatin. 2010 Jul-Aug Pharm Dev Technol pmid:19772392
Badawy SI et al. Effect of spray-dried mannitol on the performance of microcrystalline cellulose-based wet granulated tablet formulation. 2010 Jul-Aug Pharm Dev Technol pmid:20088677
Kaur G et al. Chitosan-carboxymethyl tamarind kernel powder interpolymer complexation: investigations for colon drug delivery. 2010 Jan-Mar Sci Pharm pmid:21179370
Stanisz B et al. Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. 2010 Jan-Feb Acta Pol Pharm pmid:20210086
Aburahma MH et al. Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid. 2010 Apr-Jun Sci Pharm pmid:21179352
Singh B et al. Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride. 2010 Apr-Jun Sci Pharm pmid:21179349
Salem HF Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats. 2010 Int J Nanomedicine pmid:21187946
Akpa MM et al. Inhibition of insulin and T3-induced fatty acid synthase by hexanoate. 2010 Lipids pmid:20811782
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
Lin YK et al. Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery. 2010 Int J Nanomedicine pmid:20309398
Seerapu S and Srinivasan BP Development and Validation of RP-HPLC Method for the Estimation of Ivabradine Hydrochloride in Tablets. 2010 Indian J Pharm Sci pmid:21695008
Kharia AA et al. Design and optimization of floating drug delivery system of acyclovir. 2010 Indian J Pharm Sci pmid:21694992
Harvey KA et al. Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. 2010 Clin Nutr pmid:19926177
Zhou Q et al. Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating. 2010 J Pharm Sci pmid:19795479
Uchimoto T et al. Lubrication properties of potential alternative lubricants, glycerin fatty acid esters, to magnesium stearate. 2010 Int J Pharm pmid:19913080
Muro M et al. A conformation and orientation model of the carboxylic group of fatty acids dependent on chain length in a Langmuir monolayer film studied by polarization-modulation infrared reflection absorption spectroscopy. 2010 J Phys Chem B pmid:20718412
Akazawa Y et al. Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis. 2010 J. Hepatol. pmid:20206402
Song HJ et al. Effect of probiotic Lactobacillus (Lacidofil® cap) for the prevention of antibiotic-associated diarrhea: a prospective, randomized, double-blind, multicenter study. 2010 J. Korean Med. Sci. pmid:21165295
Chen JL et al. Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry. 2010 World J. Gastroenterol. pmid:21155010
Kajiro H et al. Flexible two-dimensional square-grid coordination polymers: structures and functions. 2010 Int J Mol Sci pmid:21152303
Karande AD et al. Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend. 2010 Int J Pharm pmid:20472048
Akihisa T et al. Triterpene alcohol and fatty acid composition of shea nuts from seven African countries. 2010 J Oleo Sci pmid:20513968
Tripathi B and Platel K Finger millet (Eleucine coracana) flour as a vehicle for fortification with zinc. 2010 J Trace Elem Med Biol pmid:20122580
Huang WH et al. Development of liposomal salbutamol sulfate dry powder inhaler formulation. 2010 Biol. Pharm. Bull. pmid:20190418
Jeong SH and Park K Simple preparation of coated resin complexes and their incorporation into fast-disintegrating tablets. 2010 Arch. Pharm. Res. pmid:20191352
Cho KH et al. Monoacylglycerol (MAG)-oleic acid has stronger antioxidant, anti-atherosclerotic, and protein glycation inhibitory activities than MAG-palmitic acid. 2010 J Med Food pmid:20136442
Noguchi Y et al. Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice. 2010 PLoS ONE pmid:20706589
Maher AC et al. Women have higher protein content of beta-oxidation enzymes in skeletal muscle than men. 2010 PLoS ONE pmid:20700461
Wang Q et al. One-Step Synthesis of Monodisperse In-Doped ZnO Nanocrystals. 2010 Nanoscale Res Lett pmid:20672040
Pöllänen E et al. Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle. 2010 Age (Dordr) pmid:20640546
Dasu K et al. Hydrolysis of fluorotelomer compounds leading to fluorotelomer alcohol production during solvent extractions of soils. 2010 Chemosphere pmid:20801485
Moore F et al. Improving the hardness of dry granulated tablets containing sodium lauryl sulfate. 2010 Int J Pharm pmid:20801204
Chen X et al. Plasma metabolomics reveals biomarkers of the atherosclerosis. 2010 J Sep Sci pmid:20730840
Shidhaye SS et al. Buccal drug delivery of pravastatin sodium. 2010 AAPS PharmSciTech pmid:20300898
Ion G et al. Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring. 2010 BMC Cancer pmid:20205934
Mas S et al. Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes. 2010 Diabetes pmid:20200316
Kurian GA et al. Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. 2010 Chin Med pmid:20180993
Taneri F et al. In vitro and in vivo evaluation of oral tablet formulations prepared with ketoconazole and hydroxypropyl-beta-cyclodextrin. 2010 Drug Deliv pmid:20148713
Wang J et al. Lubrication in tablet formulations. 2010 Eur J Pharm Biopharm pmid:20096779
Dong J et al. Cation-controlled crystal growth of silver stearate: cryo-TEM investigation of lithium vs sodium stearate. 2010 Langmuir pmid:20017506
Fu X et al. A rapid and universal bacteria-counting approach using CdSe/ZnS/SiO2 composite nanoparticles as fluorescence probe. 2010 Anal Bioanal Chem pmid:20016878
Kushner J and Moore F Scale-up model describing the impact of lubrication on tablet tensile strength. 2010 Int J Pharm pmid:20667504
Imae R et al. Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. 2010 Mol. Biol. Cell pmid:20668164
Su C et al. A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC. 2010 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:20732836
Yeop Han C et al. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. 2010 Diabetes pmid:19934003