stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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SHORE PA and ALPERS HS | PLATELET DAMAGE INDUCED IN PLASMA BY CERTAIN FATTY ACIDS. | 1963 | Nature | pmid:14098491 |
YOUNG RJ and GARRETT RL | EFFECT OF OLEIC AND LINOLEIC ACIDS ON THE ABSORPTION OF SATURATED FATTY ACIDS IN THE CHICK. | 1963 | J. Nutr. | pmid:14100991 |
GOUERE P | [BIOCHEMICAL ASPECT AND DIETETIC ROLE OF GRAPE SEED OIL]. | 1963 | Aliment Vie | pmid:14135213 |
LAMBIOTTE M | [USE OF RADIOACTIVE CHOLESTEROL IN THE STUDY OF THE INFLUENCE OF DIETARY LIPIDS ON CHOLESTEROL METABOLISM]. | 1963 | Ann Nutr Aliment | pmid:14048747 |
SHIFRINE M and MARR AG | THE REQUIREMENT OF FATTY ACIDS BY PITYROSPORUM OVALE. | 1963 | J. Gen. Microbiol. | pmid:14053273 |
SOLOFF LA and WIEDEMAN MP | BIOMICROSCOPIC OBSERVATIONS ON VASOCONSTRICTIVE AND THROMBOGENIC EFFECTS PRODUCED BY LONG-CHAIN SATURATED FATTY ACIDS WITHIN THE VASCULATURE OF THE WING OF AN UNANAESTHETIZED BAT. | 1963 | Nature | pmid:14058613 |
ROUS S and FAVARGER P | [ROLE OF DEGRADATION IN THE MAINTENANCE OF THE COMPOSITION OF RESERVE FATTY ACIDS]. | 1963 | Helv Physiol Pharmacol Acta | pmid:14058926 |
GOMPERTZ SM and SAMMONS HG | THE ORIGIN OF FAECAL LIPIDS. THE COMPOSITION OF FAECAL FATSIN HUMAN SUBJECTS. | 1963 | Clin. Chim. Acta | pmid:14063975 |
DEMPSKI RE et al. | Permeability of excised human keratin to lipid-soluble substances. II. | 1963 | J Pharm Sci | pmid:14026933 |
HALL PF et al. | Synthesis of fatty acids by testicular tissue in vitro. | 1963 | Can J Biochem Physiol | pmid:13952129 |
HUEPER WC and PAYNE WW | Polyoxyethylene(8)stearate. Carcinogenic studies. | 1963 | Arch. Environ. Health | pmid:13955486 |
KORN ED | FATTY ACIDS OF ACANTHAMOEBA SP. | 1963 | J. Biol. Chem. | pmid:14109190 |
RAZIN S and ROTTEM S | FATTY ACID REQUIREMENTS OF MYCOPLASMA LAIDLAWII. | 1963 | J. Gen. Microbiol. | pmid:14114935 |
HJORTH N and TROLLE-LASSEN C | SKIN REACTIONS TO OINTMENT BASES. | 1963 | Trans St Johns Hosp Dermatol Soc | pmid:14116129 |
CALI G et al. | [GAS CHROMATOGRAPHY RESEARCH ON THE FATTY ACIDS OF HUMAN ADIPOSE TISSUE]. | 1963 | Ric Sci 2 Ser Pt 2 Rend B | pmid:14123061 |
TROUT DL and ESTES EH | Factors affecting liver uptake of serum free stearic acid-1-C14. | 1962 | Am. J. Physiol. | pmid:13994303 |
WALLEN LL et al. | The microbiological production of 10-hydroxystearic acid from oleic acid. | 1962 | Arch. Biochem. Biophys. | pmid:13998583 |
CREASEY WA | Observations on the activation of stearic acid by rat-liver preparations. | 1962 | Biochim. Biophys. Acta | pmid:14023748 |
BARGONI N and SISINI A | [Inhibition and reactivation of the hydrolases of digestion]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13966663 |
NIELSEN K and SCHMIDT H | [Should the standard treatment of gonorrhea be changed? Effects of the treatment of gonorrhea in 1960 in ambulant and hospitalized patients]. | 1962 | Manedsskr Prakt Laegegern | pmid:13938514 |