stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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CONIGLIO JG and CATE DL | The distribution and biosynthesis of palmitic and stearic acids in liver, intestine, and carcass of intact normal and fasted rats. | 1958 | J. Biol. Chem. | pmid:13549425 |
DAWSON RM | The labelling of ram semen in vivo with radioactive phosphate and [carboxy-14C] stearic acid. | 1958 | Biochem. J. | pmid:13522653 |
FABER JS | A note on the assay of zinc stearate. | 1957 | J Am Pharm Assoc Am Pharm Assoc | pmid:13491438 |
BRZEZINSKI A et al. | Prolonged effect of riboflavin: aluminum monostearate suspensions in man. | 1957 | J Am Pharm Assoc Am Pharm Assoc | pmid:13438726 |
KARVINEN E et al. | Effect of palmitic and stearic acid on cholesterol absorption in man. | 1957 | J Appl Physiol | pmid:13462909 |
GLASCOCK RF and REINIUS LR | Studies on the origin of milk fat. 1. The location of tritium in stearic acid produced by the catalytic addition of tritium to elaidic acid. | 1956 | Biochem. J. | pmid:13315207 |
TOVE SB et al. | Turnover of palmitic, stearic, and unsaturated fatty acids in rat liver. | 1956 | J. Biol. Chem. | pmid:13278335 |
MEAD JF et al. | Metabolism of the essential fatty acids. II. The metabolism of stearate, oleate, and linoleate by fat-deficient and normal mice. | 1956 | J. Biol. Chem. | pmid:13278347 |
BLOMSTRAND R et al. | On the intestinal absorption of 2, 2-dimethylstearic acid fed as free acid or as glyceride. | 1956 | Acta Physiol. Scand. | pmid:13339456 |
KERN W et al. | [Suggestions for the composition of the general section on ointments and salve bases and emulsifiers in the German Pharmacopeia (DAB 6, Annex). II]. | 1956 | Hautarzt | pmid:13345190 |
Buensod M and Favarger P | [Observations on the digestibility of palmitic and stearic acids and their glyceric esters in rats]. | 1956 | Helv Physiol Pharmacol Acta | pmid:13405350 |
COOKE NJ et al. | The branched-chain fatty acids of mutton fat. 3. The isolation of 16-methylheptadecanoic acid (isostearic acid). | 1956 | Biochem. J. | pmid:13363830 |
JAMES AT and MARTIN AJ | Gas-liquid chromatography: the separation and identification of the methyl esters of saturated and unsaturated acids from formic acid to n-octadecanoic acid. | 1956 | Biochem. J. | pmid:13315260 |
HUME JC and FACIO G | An analysis of the results of the treatment of yaws with a single injection of procaine penicillin with 2% aluminium monostearate. | 1956 | Bull. World Health Organ. | pmid:13404472 |
MUNZEL K and AMMANN R | [Contributions on the character of water-soluble fatty ointments. X. Quasiviscosity determination of stearate ointments]. | 1955 | Pharm Acta Helv | pmid:13289260 |
SULMAN FG | A note on the resorption and excretion of riboflavine from aluminium monostearate suspensions in the rat. | 1955 | J. Pharm. Pharmacol. | pmid:14392601 |
POLYOXYETHYLENE stearates in food. | 1955 | Nutr. Rev. | pmid:14394517 | |
DAMMANN F | [Antiphlogistic percutaneous therapy with choline stearate (chomelan)]. | 1955 | Medizinische | pmid:14355526 |
GEYER RP et al. | Aerobic C14O2 formation from carboxyl-labeled stearic and palmitic acids in the presence of ascorbic acid. | 1955 | Arch. Biochem. Biophys. | pmid:14377605 |
MUNZEL K and AMMANN R | [On washable fat-in-water ointments. IV. Stearate ointments]. | 1954 | Pharm Acta Helv | pmid:13166515 |