stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kashefi K et al. | Geoglobus ahangari gen. nov., sp. nov., a novel hyperthermophilic archaeon capable of oxidizing organic acids and growing autotrophically on hydrogen with Fe(III) serving as the sole electron acceptor. | 2002 | Int. J. Syst. Evol. Microbiol. | pmid:12054231 |
Aveldano MI and Bazán NG | Rapid production of diacylglycerols enriched in arachidonate and stearate during early brain ischemia. | 1975 | J. Neurochem. | pmid:1206411 |
Williams RO et al. | Investigation of excipient type and level on drug release from controlled release tablets containing HPMC. | 2002 | Pharm Dev Technol | pmid:12066573 |
Liu Q et al. | High-oleic and high-stearic cottonseed oils: nutritionally improved cooking oils developed using gene silencing. | 2002 | J Am Coll Nutr | pmid:12071306 |
Schmidt LE and Dalhoff K | Food-drug interactions. | 2002 | Drugs | pmid:12093316 |
Liang X et al. | Mass spectrometric analysis of GAP-43/neuromodulin reveals the presence of a variety of fatty acylated species. | 2002 | J. Biol. Chem. | pmid:12105219 |
Anwar F et al. | Analytical characterization of Salicornia bigelovii seed oil cultivated in Pakistan. | 2002 | J. Agric. Food Chem. | pmid:12105947 |
Sebti I et al. | Edible bioactive fatty acid-cellulosic derivative composites used in food-packaging applications. | 2002 | J. Agric. Food Chem. | pmid:12105960 |
Østdal H et al. | Reaction between protein radicals and other biomolecules. | 2002 | Free Radic. Biol. Med. | pmid:12106816 |
Cao X et al. | Langmuir and Langmuir-Blodgett films of a novel tryptophan peptide lipid. | 2002 | Chem. Commun. (Camb.) | pmid:12122989 |