stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ragnarsson G and Sjögren J | Force-displacement measurements in tableting. | 1985 | J. Pharm. Pharmacol. | pmid:2858558 |
| Esezobo S | The effect of some excipients on the physical properties of a paracetamol tablet formulation. | 1985 | J. Pharm. Pharmacol. | pmid:2858567 |
| Zoeller RA and Wood R | The importance of the stearoyl-CoA desaturase system in octadecenoate metabolism in the Morris hepatoma 7288C. | 1985 | Biochim. Biophys. Acta | pmid:2860925 |
| Bangudu AB and Pilpel N | Effects of composition, moisture and stearic acid on the plasto-elasticity and tableting of paracetamol-microcrystalline cellulose mixtures. | 1985 | J. Pharm. Pharmacol. | pmid:2862234 |
| Onoda T et al. | Antitumor activity of D-mannosamine in vitro: cytotoxic effect produced by mannosamine in combination with free fatty acids on human leukemia T-cell lines. | 1985 | Jpn. J. Clin. Oncol. | pmid:3877190 |
| Shanson DC et al. | Erythromycin stearate, 1.5 g, for the oral prophylaxis of streptococcal bacteraemia in patients undergoing dental extraction: efficacy and tolerance. | 1985 | J. Antimicrob. Chemother. | pmid:3882657 |
| Politi LE et al. | Dexamethasone effect on free fatty acid and diacylglycerol accumulation during experimentally induced vasogenic brain edema. | 1985 | Neurochem Pathol | pmid:3831846 |
| Johansson ME | Investigations of the mixing time dependence of the lubricating properties of granular and powdered magnesium stearate. | 1985 | Acta Pharm. Suec. | pmid:3832785 |
| Goto S et al. | [Effect of magnesium stearate in preparation of eudragit RS-microcapsules containing drugs]. | 1985 | Yakugaku Zasshi | pmid:3835255 |
| Roblot L et al. | Effect of lubricant level and applied compressional pressure on surface friction of tablets. | 1985 | J Pharm Sci | pmid:4020661 |
| Fujii M et al. | Fatty acid compositions of triacylglycerols and phospholipids in hen liver lipid before and after sexual maturity. | 1985 | Poult. Sci. | pmid:4022907 |
| Carranco E et al. | Carbamazepine toxicity induced by concurrent erythromycin therapy. | 1985 | Arch. Neurol. | pmid:3977647 |
| Ruwart MJ et al. | 16,16-Dimethyl PGE2 and fatty acids protect hepatocytes against CCl4-induced damage. | 1985 | In Vitro Cell. Dev. Biol. | pmid:4030626 |
| Sklan D et al. | Digestion and absorption of lipids and bile acids in sheep fed stearic acid, oleic acid, or tristearin. | 1985 | J. Dairy Sci. | pmid:4031186 |
| Bridges CD et al. | Vitamin A and interstitial retinol-binding protein in an eye with recessive retinitis pigmentosa. | 1985 | Invest. Ophthalmol. Vis. Sci. | pmid:4039711 |
| Beckurts TE et al. | Kinetics of different 123I- and 14C-labelled fatty acids in normal and diabetic rat myocardium in vivo. | 1985 | Nucl Med Commun | pmid:4047532 |
| Plachy J et al. | In vitro biopharmaceutical test for wetting rate. | 1985 | Acta Pharm Hung | pmid:4050448 |
| Griffiths G et al. | The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. | 1985 | Biochem. J. | pmid:4052051 |
| Stubbs C et al. | Determination of erythromycin in serum and urine by high-performance liquid chromatography with ultraviolet detection. | 1985 | J Pharm Sci | pmid:4078714 |
| Baker RR and Loh ZD | The subcellular distribution of free fatty acids released during post-decapitative ischemia in rat cerebral cortex. | 1985 | Can. J. Biochem. Cell Biol. | pmid:4084856 |
| Crutchley DJ | Hydroxyeicosatetraenoic acids and other unsaturated fatty acids inhibit endotoxin-induced thromboplastin activity in human monocytes. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2865954 |
| Johansson ME | Influence of the granulation technique and starting material properties on the lubricating effect of granular magnesium stearate. | 1985 | J. Pharm. Pharmacol. | pmid:2867134 |
| Staniforth JN | Relationship between particle packing and the physical stability of powder mixes. | 1985 | J. Pharm. Pharmacol. | pmid:2867136 |
| Schreiner A and Digranes A | Absorption of erythromycin stearate and enteric-coated erythromycin base after a single oral dose immediately before breakfast. | 1984 Sep-Oct | Infection | pmid:6511088 |
| Blackett PR et al. | Hyperlipidemia in acute lymphoblastic leukemia. | 1984 Mar-Apr | Ann. Clin. Lab. Sci. | pmid:6585175 |
| Hanna GM | Nuclear magnetic resonance spectroscopic determination of dicyclomine hydrochloride in tablet, capsule, and injection dosage forms. | 1984 Mar-Apr | J Assoc Off Anal Chem | pmid:6725188 |
| Holub BJ and Celi B | Evaluation of the fatty acid selectivity of a phosphatidylinositol-specific cytosolic phospholipase C from pig and human platelets. | 1984 Feb-Mar | Can. J. Biochem. Cell Biol. | pmid:6518412 |
| Ras GJ et al. | Chemoprophylaxis with erythromycin stearate or amoxycillin in patients with chronic bronchitis--effects on cellular and humoral immune functions. | 1984 Dec 22-29 | S. Afr. Med. J. | pmid:6515508 |
| Abdulrazik M et al. | Formulation for slow release of oral radiation-protection drugs. | 1984 | Int J Nucl Med Biol | pmid:6610665 |
| Kemp P et al. | The hydrogenation of some cis- and trans-octadecenoic acids to stearic acid by a rumen Fusocillus sp. | 1984 | Br. J. Nutr. | pmid:6743636 |
| Greenberg DS et al. | Fatty acid composition of lizard tissue lipids and the effects of estradiol on serum free fatty acids. | 1984 | Comp. Biochem. Physiol., B | pmid:6744817 |
| MacDonald RC et al. | Inhibition of sendai virus-induced hemolysis by long chain fatty acids. | 1984 | Virology | pmid:6324464 |
| Goldberg I et al. | Gangrene of the upper extremity following intra-arterial injection of drugs. A case report and review of the literature. | 1984 | Clin. Orthop. Relat. Res. | pmid:6380862 |
| Buttke TM and Cuchens MA | Inhibition of lymphocyte proliferation by free fatty acids. II. Toxicity of stearic acid towards phytohaemagglutinin-activated T cells. | 1984 | Immunology | pmid:6333387 |
| Walstad RA and Hellum KB | Penetration of erythromycin in respiratory tract infections. | 1984 | Acta Otolaryngol Suppl | pmid:6333775 |
| Shanson DC et al. | The pharmacokinetics and tolerance of oral erythromycin stearate compared with erythromycin ethylsuccinate: implications for preventing endocarditis. | 1984 | J. Antimicrob. Chemother. | pmid:6334070 |
| Tjandramaga TB et al. | Relative bioavailability of enteric coated pellets, stearate and ethylsuccinate formulations of erythromycin. | 1984 | Pharmacology | pmid:6334320 |
| Ohki K et al. | Effect of alpha-tocopherol on lipid peroxidation and acyl chain mobility of liver microsomes from vitamin E-difficient rat. | 1984 | J. Nutr. Sci. Vitaminol. | pmid:6092586 |
| Lem NW and Stumpf PK | In Vitro Fatty Acid Synthesis and Complex Lipid Metabolism in the Cyanobacterium, Anabaena Variabilis: II. Acyl Transfer and Complex Lipid Formation. | 1984 | Plant Physiol. | pmid:16663690 |
| Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |
| Zoeller RA and Wood R | Effects of cyclopropene fatty acids on the lipid composition of the Morris hepatoma 7288C. | 1984 | Lipids | pmid:6431218 |
| Sivarajan M et al. | Regulation of intracellular arachidonate in normal and stressed endothelial cells. | 1984 | Biochim. Biophys. Acta | pmid:6433983 |
| Rosén C et al. | Acute otitis media in older children and adults treated with penicillin or erythromycin. | 1984 | Acta Otolaryngol Suppl | pmid:6437133 |
| Dixon JF and Hokin LE | Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase. | 1984 | J. Biol. Chem. | pmid:6438097 |
| Forsberg NE et al. | Roles of acetate and its interactions with glucose and lactate in cow mammary tissue. | 1984 | J. Dairy Sci. | pmid:6438200 |
| Desudchit P et al. | Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men. | 1984 | Southeast Asian J. Trop. Med. Public Health | pmid:6441265 |
| Hunter JM and Sommerville RG | Erythromycin stearate in treating chlamydial infection of the cervix. | 1984 | Br J Vener Dis | pmid:6518350 |
| Farkas T | Adaptation of fatty acid composition to temperature--a study on carp (Cyprinus carpio L.) liver slices. | 1984 | Comp. Biochem. Physiol., B | pmid:6518757 |
| Magill A and Becker AR | Spectrophotometric method for quantitation of peroxides in sorbitan monooleate and monostearate. | 1984 | J Pharm Sci | pmid:6520780 |
| Ueda A et al. | Experimental study on the pathological changes in lung tissue caused by zinc stearate dust. | 1984 | Ind Health | pmid:6526700 |