stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Jójárt I et al. | Study of the compressibility of chewing gum and its applicability as an oral drug delivery system. | 2016 | Pharm Dev Technol | pmid:25673279 |
Patadia R et al. | Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets. | 2016 | Pharm Dev Technol | pmid:25566928 |
Souza AF et al. | Waste Soybean Oil and Corn Steep Liquor as Economic Substrates for Bioemulsifier and Biodiesel Production by Candida lipolytica UCP 0998. | 2016 | Int J Mol Sci | pmid:27669227 |
Teh SS et al. | Incorporation of Palmitic Acid or Stearic Acid into Soybean Oils Using Enzymatic Interesterification. | 2016 | J Oleo Sci | pmid:27477075 |
Sun Y et al. | Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study. | 2016 | J. Lipid Res. | pmid:27371261 |
Du H et al. | Modification of the fatty acid composition in Arabidopsis and maize seeds using a stearoyl-acyl carrier protein desaturase-1 (ZmSAD1) gene. | 2016 | BMC Plant Biol. | pmid:27297560 |
Sorigué D et al. | Microalgae Synthesize Hydrocarbons from Long-Chain Fatty Acids via a Light-Dependent Pathway. | 2016 | Plant Physiol. | pmid:27288359 |
Jeyanathan J et al. | Biohydrogenation of 22:6n-3 by Butyrivibrio proteoclasticus P18. | 2016 | BMC Microbiol. | pmid:27283157 |
Mazel V et al. | Reevaluation of the diametral compression test for tablets using the flattened disc geometry. | 2016 | Int J Pharm | pmid:27702696 |
Nie H et al. | Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in Solid-State Formulations. | 2016 | Mol. Pharm. | pmid:27542728 |
Hu Y et al. | Sequential delivery of therapeutic agents using a rationally designed disulfide-linked glycolipid-like nanocarrier. | 2016 | Oncotarget | pmid:27825127 |
Billès E et al. | Cellulose oligomers production and separation for the synthesis of new fully bio-based amphiphilic compounds. | 2016 | Carbohydr Polym | pmid:27577903 |
Krasnou I et al. | Permeability of water and oleic acid in composite films of phase separated polypropylene and cellulose stearate blends. | 2016 | Carbohydr Polym | pmid:27516292 |
Liu L et al. | Decreasing high postprandial stearic acid in impaired fasting glucose by dietary regulation. | 2016 | Eur J Clin Nutr | pmid:26733041 |
Thilakarathna SH et al. | Investigations of in vitro bioaccessibility from interesterified stearic and oleic acid-rich blends. | 2016 | Food Funct | pmid:26961726 |
Ma F et al. | Improvement of β-TCP/PLLA biodegradable material by surface modification with stearic acid. | 2016 | Mater Sci Eng C Mater Biol Appl | pmid:26952440 |
Zhang C et al. | Design and evaluation of an innovative floating and bioadhesive multiparticulate drug delivery system based on hollow structure. | 2016 | Int J Pharm | pmid:26943975 |
Zhang Y et al. | CO2/pH-Controllable Viscoelastic Nanostructured Fluid Based on Stearic Acid Soap and Bola-Type Quaternary Ammonium Salt. | 2016 | Langmuir | pmid:26907546 |
Wang S et al. | Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. | 2016 | Biochem. Biophys. Res. Commun. | pmid:26879142 |
Lohan SB et al. | Investigation of cutaneous penetration properties of stearic acid loaded to dendritic core-multi-shell (CMS) nanocarriers. | 2016 | Int J Pharm | pmid:26853315 |