stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Lee BJ et al. | Preparation and characterization of melatonin-loaded stearyl alcohol microspheres. | 1998 Nov-Dec | J Microencapsul | pmid:9818955 |
Müller K et al. | Cell-mediated oxidation of LDL: comparison of different cell types of the atherosclerotic lesion. | 1998 | Free Radic. Res. | pmid:9802552 |
Sekulic SS et al. | Automated system for the on-line monitoring of powder blending processes using near-infrared spectroscopy. Part II. Qualitative approaches to blend evaluation. | 1998 | J Pharm Biomed Anal | pmid:9800649 |
Nicolosi RJ et al. | Effects of specific fatty acids (8:0, 14:0, cis-18:1, trans-18:1) on plasma lipoproteins, early atherogenic potential, and LDL oxidative properties in the hamster. | 1998 | J. Lipid Res. | pmid:9788243 |
White RG and Feist DD | Stearic acid oxidation in the Alaskan red-backed vole: effects of cold and norepinephrine. | 1998 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:9787830 |
Matsuda Y et al. | Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression. | 1976 | J Pharm Sci | pmid:978434 |
Graham KC et al. | Simple thin-layer chromatographic identification method for erythromycin stearate. | 1976 | J. Chromatogr. | pmid:977688 |
Merlo AO et al. | Ribozymes targeted to stearoyl-ACP delta9 desaturase mRNA produce heritable increases of stearic acid in transgenic maize leaves. | 1998 | Plant Cell | pmid:9761789 |
Matorras R et al. | Fatty acid composition of fertilization-failed human oocytes. | 1998 | Hum. Reprod. | pmid:9756301 |
Sentex E et al. | Is the cytoprotective effect of trimetazidine associated with lipid metabolism? | 1998 | Am. J. Cardiol. | pmid:9737482 |