| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Burns | D002056 | 34 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Harvey DJ | Picolinyl esters for the structural determination of fatty acids by GC/MS. | 1998 | Mol. Biotechnol. | pmid:9951705 |
| Avdulov NA et al. | Lipid binding to sterol carrier protein-2 is inhibited by ethanol. | 1999 | Biochim. Biophys. Acta | pmid:9931423 |
| Jang Y et al. | Low-calorie structured lipid synthesis by lipase-catalyzed transesterification. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9928107 |
| Weber J et al. | [Can zinc stearate cause lung fibrosis? (Case report)]. | 1976 | Beitr Silikoseforsch Pneumokoniose | pmid:990095 |
| Porra RJ and Stumpf PK | Lipid biosynthesis in developing and germinating soybean cotyledons. The formation of palmitate and stearate by chopped tissue and supernatant preparations. | 1976 | Arch. Biochem. Biophys. | pmid:987755 |
| Diani F et al. | [Fatty acid composition of the cervical mucus obtained during ovulation and at the term of pregnancy]. | 1998 | Minerva Ginecol | pmid:9866950 |
| Malykh EV et al. | Effect of hydrophobization of basic pancreatic proteinase inhibitor on the inhibition of bovine trypsin and human leukocyte elastase. | 1998 | Biochemistry Mosc. | pmid:9864442 |
| Adachi H et al. | Effect of long-chain acyl-CoA on the omega-oxidation of monocarboxylic acid. | 1976 | Hokkaido Igaku Zasshi | pmid:985795 |
| Lu G et al. | Reactive oxygen species are critical in the oleic acid-mediated mitogenic signaling pathway in vascular smooth muscle cells. | 1998 | Hypertension | pmid:9856964 |
| Engelbrecht AM et al. | Comparison of the fatty acid compositions in intraepithelial and infiltrating lesions of the cervix: part II, free fatty acid profiles. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9849651 |
| Lee BJ et al. | Preparation and characterization of melatonin-loaded stearyl alcohol microspheres. | 1998 Nov-Dec | J Microencapsul | pmid:9818955 |
| Müller K et al. | Cell-mediated oxidation of LDL: comparison of different cell types of the atherosclerotic lesion. | 1998 | Free Radic. Res. | pmid:9802552 |
| Sekulic SS et al. | Automated system for the on-line monitoring of powder blending processes using near-infrared spectroscopy. Part II. Qualitative approaches to blend evaluation. | 1998 | J Pharm Biomed Anal | pmid:9800649 |
| Nicolosi RJ et al. | Effects of specific fatty acids (8:0, 14:0, cis-18:1, trans-18:1) on plasma lipoproteins, early atherogenic potential, and LDL oxidative properties in the hamster. | 1998 | J. Lipid Res. | pmid:9788243 |
| White RG and Feist DD | Stearic acid oxidation in the Alaskan red-backed vole: effects of cold and norepinephrine. | 1998 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:9787830 |
| Matsuda Y et al. | Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression. | 1976 | J Pharm Sci | pmid:978434 |
| Graham KC et al. | Simple thin-layer chromatographic identification method for erythromycin stearate. | 1976 | J. Chromatogr. | pmid:977688 |
| Merlo AO et al. | Ribozymes targeted to stearoyl-ACP delta9 desaturase mRNA produce heritable increases of stearic acid in transgenic maize leaves. | 1998 | Plant Cell | pmid:9761789 |
| Matorras R et al. | Fatty acid composition of fertilization-failed human oocytes. | 1998 | Hum. Reprod. | pmid:9756301 |
| Sentex E et al. | Is the cytoprotective effect of trimetazidine associated with lipid metabolism? | 1998 | Am. J. Cardiol. | pmid:9737482 |