stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Breast Neoplasms D001943 24 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Wang ZJ et al. Stearic acid protects primary cultured cortical neurons against oxidative stress. 2007 Acta Pharmacol. Sin. pmid:17302992
Zhang XX et al. Effects of breast cancer resistance protein inhibitors and pharmaceutical excipients on decreasing gastrointestinal toxicity of camptothecin analogs. 2008 Acta Pharmacol. Sin. pmid:18954535
Tierno MA and Brenner RR [Biochemistry of the developmental cycle of Triatoma infestans (Vinchuca). 2. Biosynthesis of fatty acids]. 1979 Acta Physiol Lat Am pmid:400672
Catalá A Stearic acid desaturation in rat liver microsomes: stimulation by fatty acid binding protein. 1986 Acta Physiol Pharmacol Latinoam pmid:2876583
Zanetti R and Catalá A Lipid binding properties of fatty acid binding protein isolated from mouse liver. 1988 Acta Physiol Pharmacol Latinoam pmid:3201993
BLOMSTRAND R et al. On the intestinal absorption of 2, 2-dimethylstearic acid fed as free acid or as glyceride. 1956 Acta Physiol. Scand. pmid:13339456
GOERANSSON G THE METABOLISM OF FATTY ACIDS IN THE RAT. IV. STEARIC ACID. 1965 Acta Physiol. Scand. pmid:14321752
Muzíková J and Sináglová P Comparison of properties of tablets and energy profile of compaction of two spray-dried lactoses. 2013 Jan-Feb Acta Pol Pharm pmid:23610968
Hussain T et al. Effect of two hydrophobic polymers on the release of gliclazide from their matrix tablets. 2013 Jul-Aug Acta Pol Pharm pmid:23923399
Muzíková J et al. A study of micronized poloxamers as lubricants in direct compression of tablets. 2013 Nov-Dec Acta Pol Pharm pmid:24383332