18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

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All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Hung CF et al. 18ß-glycyrrhetinic acid derivative promotes proliferation, migration and aquaporin-3 expression in human dermal fibroblasts. 2017 PLoS ONE pmid:28813533
Suswillo RF et al. Strain uses gap junctions to reverse stimulation of osteoblast proliferation by osteocytes. 2017 Cell Biochem. Funct. pmid:28083967
Zhu Y et al. Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. 2016 Cell Metab. pmid:27626200
Queiroga CS et al. Paracrine effect of carbon monoxide - astrocytes promote neuroprotection through purinergic signaling in mice. 2016 J. Cell. Sci. pmid:27383770
Huang YC et al. 18α-Glycyrrhetinic Acid Induces Apoptosis of HL-60 Human Leukemia Cells through Caspases- and Mitochondria-Dependent Signaling Pathways. 2016 Molecules pmid:27376261
Ikarashi Y and Mizoguchi K Neuropharmacological efficacy of the traditional Japanese Kampo medicine yokukansan and its active ingredients. 2016 Pharmacol. Ther. pmid:27373856
Yu J et al. Endometrial Stromal Decidualization Responds Reversibly to Hormone Stimulation and Withdrawal. 2016 Endocrinology pmid:27035651
Cao D et al. The Protective Effects of 18β-Glycyrrhetinic Acid on Helicobacter pylori-Infected Gastric Mucosa in Mongolian Gerbils. 2016 Biomed Res Int pmid:27006947
Li SN et al. Effect of Connexin43 on Mechanical Tension-stimulated Osteogenic Transcription Factors of Human Periodontal Ligament Fibroblasts. 2016 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:26956851
Papaevgeniou N et al. 18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures. 2016 Antioxid. Redox Signal. pmid:26886723
Yamada A et al. Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation. 2016 J. Biol. Chem. pmid:26565022
Takeuchi R et al. Possible pharmacotherapy for nifedipine-induced gingival overgrowth: 18α-glycyrrhetinic acid inhibits human gingival fibroblast growth. 2016 Br. J. Pharmacol. pmid:26676684
Zhou J et al. 18β-glycyrrhetinic acid suppresses experimental autoimmune encephalomyelitis through inhibition of microglia activation and promotion of remyelination. 2015 Sci Rep pmid:26329786
Zhang H et al. Structural basis for 18-β-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor. 2015 Acta Pharmacol. Sin. pmid:26279158
Kitagawa H et al. Pharmacokinetics of Active Components of Yokukansan, a Traditional Japanese Herbal Medicine after a Single Oral Administration to Healthy Japanese Volunteers: A Cross-Over, Randomized Study. 2015 PLoS ONE pmid:26151135
Qu Y et al. Effects of 18α-glycyrrhizin on TGF-β1/Smad signaling pathway in rats with carbon tetrachloride-induced liver fibrosis. 2015 Int J Clin Exp Pathol pmid:25973013
Gupta P et al. Antileishmanial effect of 18β-glycyrrhetinic acid is mediated by Toll-like receptor-dependent canonical and noncanonical p38 activation. 2015 Antimicrob. Agents Chemother. pmid:25691644
Hendricks JM et al. Differential induction of isolated lymphoid follicles in the gut by 18β-glycyrrhetinic acid. 2014 PLoS ONE pmid:24992099
Zhang W et al. [Inhibitory effect of 18β-glycyrrhetinic acid on KCl- and PE-induced constriction of rat renal interlobar artery in vitro]. 2014 Sheng Li Xue Bao pmid:24777410
Mizoguchi K et al. Specific binding and characteristics of 18β-glycyrrhetinic acid in rat brain. 2014 PLoS ONE pmid:24752617