18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

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All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Kuzma-Kuzniarska M et al. Functional assessment of gap junctions in monolayer and three-dimensional cultures of human tendon cells using fluorescence recovery after photobleaching. 2014 J Biomed Opt pmid:24390370
Jayasooriya RG et al. 18β-Glycyrrhetinic acid suppresses TNF-α induced matrix metalloproteinase-9 and vascular endothelial growth factor by suppressing the Akt-dependent NF-κB pathway. 2014 Toxicol In Vitro pmid:24613819
Kim YJ et al. Prevention of cisplatin-induced ototoxicity by the inhibition of gap junctional intercellular communication in auditory cells. 2014 Cell. Mol. Life Sci. pmid:24623558
Li X et al. Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp. 2014 Toxicol. Appl. Pharmacol. pmid:24380838
Mizoguchi K et al. Specific binding and characteristics of 18β-glycyrrhetinic acid in rat brain. 2014 PLoS ONE pmid:24752617
Huang RY et al. 18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer. 2014 PLoS ONE pmid:24695790
Jay M et al. Effects of nitric oxide on neuromuscular properties of developing zebrafish embryos. 2014 PLoS ONE pmid:24489806
Wong PS et al. Sex differences in endothelial function in porcine coronary arteries: a role for H2O2 and gap junctions? 2014 Br. J. Pharmacol. pmid:24467384
Yadav DK et al. Design, synthesis and in vitro evaluation of 18β-glycyrrhetinic acid derivatives for anticancer activity against human breast cancer cell line MCF-7. 2014 Curr. Med. Chem. pmid:24180274
Wang D et al. 18beta-glycyrrhetinic acid induces apoptosis in pituitary adenoma cells via ROS/MAPKs-mediated pathway. 2014 J. Neurooncol. pmid:24162829
Feng Yeh C et al. Water extract of licorice had anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. 2013 J Ethnopharmacol pmid:23643542
Kao TC et al. Glycyrrhizic acid and 18β-glycyrrhetinic acid recover glucocorticoid resistance via PI3K-induced AP1, CRE and NFAT activation. 2013 Phytomedicine pmid:23218403
Kato R et al. Gap-junction-mediated communication in human periodontal ligament cells. 2013 J. Dent. Res. pmid:23677649
Nishida S and Satoh H Role of gap junction involved with endothelium-derived hyperpolarizing factor for the quercetin-induced vasodilatation in rat mesenteric artery. 2013 Life Sci. pmid:23435092
Kim ME et al. 18β-Glycyrrhetinic acid from licorice root impairs dendritic cells maturation and Th1 immune responses. 2013 Immunopharmacol Immunotoxicol pmid:23438306
Figueroa XF et al. Diffusion of nitric oxide across cell membranes of the vascular wall requires specific connexin-based channels. 2013 Neuropharmacology pmid:23499665
Zong L et al. 18α-glycyrrhetinic acid extracted from Glycyrrhiza radix inhibits proliferation and promotes apoptosis of the hepatic stellate cell line. 2013 J Dig Dis pmid:23362936
Lallemand B et al. Synthesis and plasma pharmacokinetics in CD-1 mice of a 18β-glycyrrhetinic acid derivative displaying anti-cancer activity. 2013 J. Pharm. Pharmacol. pmid:23356849
Fu XX et al. 18β-Glycyrrhetinic acid potently inhibits Kv1.3 potassium channels and T cell activation in human Jurkat T cells. 2013 J Ethnopharmacol pmid:23707333
Kalani K et al. In silico and in vivo anti-malarial studies of 18β glycyrrhetinic acid from Glycyrrhiza glabra. 2013 PLoS ONE pmid:24086367