18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Kao TC et al. Glycyrrhizic acid and 18β-glycyrrhetinic acid recover glucocorticoid resistance via PI3K-induced AP1, CRE and NFAT activation. 2013 Phytomedicine pmid:23218403
Kuang P et al. 18β-glycyrrhetinic acid inhibits hepatocellular carcinoma development by reversing hepatic stellate cell-mediated immunosuppression in mice. 2013 Int. J. Cancer pmid:22991231
Chen H et al. Metabolism of ginger component [6]-shogaol in liver microsomes from mouse, rat, dog, monkey, and human. 2013 Mol Nutr Food Res pmid:23322474
Long DR et al. 18β-Glycyrrhetinic acid inhibits methicillin-resistant Staphylococcus aureus survival and attenuates virulence gene expression. 2013 Antimicrob. Agents Chemother. pmid:23114775
Kizub IV et al. Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization. 2013 Cardiovasc. Res. pmid:23708740
Nomura R et al. Bee venom phospholipase A2-induced phasic contractions in mouse rectum: independent roles of eicosanoid and gap junction proteins and their loss in experimental colitis. 2013 Eur. J. Pharmacol. pmid:24012929
Lee KW and Ho WS 18β-glycyrrhetinic acid induces UDP-glucuronosyltransferase in rats. 2013 Protein Pept. Lett. pmid:24261979
Kalani K et al. In silico and in vivo anti-malarial studies of 18β glycyrrhetinic acid from Glycyrrhiza glabra. 2013 PLoS ONE pmid:24086367
Matsumoto T et al. The anti-ulcer agent, irsogladine, increases insulin secretion by MIN6 cells. 2012 Eur. J. Pharmacol. pmid:22542662
Niger C et al. ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts. 2012 Am. J. Physiol., Cell Physiol. pmid:22277757
Suh HN et al. Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA-mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex. 2012 Stem Cells Dev. pmid:22150760
Boengler K et al. Mitochondrial connexin 43 impacts on respiratory complex I activity and mitochondrial oxygen consumption. 2012 J. Cell. Mol. Med. pmid:22212640
Goerke SM et al. Human endothelial progenitor cells induce extracellular signal-regulated kinase-dependent differentiation of mesenchymal stem cells into smooth muscle cells upon cocultivation. 2012 Tissue Eng Part A pmid:22731749
Fujiwara H et al. Endothelium-derived relaxing factor-mediated vasodilation in mouse mesenteric vascular beds. 2012 J. Pharmacol. Sci. pmid:22450195
Shahidullah M et al. TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. 2012 Am. J. Physiol., Cell Physiol. pmid:22492652
Li L et al. Myoendothelial coupling is unidirectional in guinea pig spiral modiolar arteries. 2012 Microvasc. Res. pmid:22580342
Yang JC et al. 18β-glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway. 2012 Mol. Cell. Biochem. pmid:22865487
Li S et al. A novel transdermal fomulation of 18β-glycyrrhetic acid with lysine for improving bioavailability and efficacy. 2012 Skin Pharmacol Physiol pmid:22832704
Liu Y et al. Synthesis and biological evaluation of novel spin labeled 18β-glycyrrhetinic acid derivatives. 2012 Bioorg. Med. Chem. Lett. pmid:23122524
Du YM et al. 18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels. 2012 Acta Pharmacol. Sin. pmid:22609834