18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

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All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Zhang H et al. Structural basis for 18-β-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor. 2015 Acta Pharmacol. Sin. pmid:26279158
De Blasio BF et al. Global, synchronous oscillations in cytosolic calcium and adherence in bradykinin-stimulated Madin-Darby canine kidney cells. 2004 Acta Physiol. Scand. pmid:15030375
Guo Y et al. Inhibition of gap junction communication in alveolar epithelial cells by 18alpha-glycyrrhetinic acid. 1999 Am. J. Physiol. pmid:10362727
Ruiz-Meana M et al. Persistence of gap junction communication during myocardial ischemia. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11356611
Rodríguez-Sinovas A et al. Protective effect of gap junction uncouplers given during hypoxia against reoxygenation injury in isolated rat hearts. 2006 Am. J. Physiol. Heart Circ. Physiol. pmid:16183732
Lagaud G et al. Inhibitors of gap junctions attenuate myogenic tone in cerebral arteries. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:12427590
Luksha L et al. Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites. 2008 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:18032472
Ikeda Y et al. Role of gap junctions in spontaneous activity of the rat bladder. 2007 Am. J. Physiol. Renal Physiol. pmid:17581924
Niger C et al. ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts. 2012 Am. J. Physiol., Cell Physiol. pmid:22277757
Shahidullah M et al. TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. 2012 Am. J. Physiol., Cell Physiol. pmid:22492652
Veratti E et al. 18beta-glycyrrhetinic acid and glabridin prevent oxidative DNA fragmentation in UVB-irradiated human keratinocyte cultures. 2011 Anticancer Res. pmid:21737643
Gupta P et al. Antileishmanial effect of 18β-glycyrrhetinic acid is mediated by Toll-like receptor-dependent canonical and noncanonical p38 activation. 2015 Antimicrob. Agents Chemother. pmid:25691644
Long DR et al. 18β-Glycyrrhetinic acid inhibits methicillin-resistant Staphylococcus aureus survival and attenuates virulence gene expression. 2013 Antimicrob. Agents Chemother. pmid:23114775
Papaevgeniou N et al. 18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures. 2016 Antioxid. Redox Signal. pmid:26886723
Seul KH et al. Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis. 2004 Biochem. Biophys. Res. Commun. pmid:15194487
Fujino H and Regan JW Prostaglandin F2alpha amplifies tumor necrosis factor-alpha promoter activity by the FPB prostanoid receptor. 2004 Biochem. Biophys. Res. Commun. pmid:15094384
Ransjö M et al. Expression of connexin 43 mRNA in microisolated murine osteoclasts and regulation of bone resorption in vitro by gap junction inhibitors. 2003 Biochem. Biophys. Res. Commun. pmid:12684060
Griffith TM and Taylor HJ Cyclic AMP mediates EDHF-type relaxations of rabbit jugular vein. 1999 Biochem. Biophys. Res. Commun. pmid:10486252
Matoba T et al. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries. 2002 Biochem. Biophys. Res. Commun. pmid:11798159
Moon MH et al. 18β-Glycyrrhetinic acid inhibits adipogenic differentiation and stimulates lipolysis. 2012 Biochem. Biophys. Res. Commun. pmid:22465130