18alpha-glycyrrhetinic acid

18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.

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Introduction

To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18alpha-glycyrrhetinic acid?

18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

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PubChem Associated disorders and diseases

What pathways are associated with 18alpha-glycyrrhetinic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What functions are associated with 18alpha-glycyrrhetinic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 18alpha-glycyrrhetinic acid?

There are no associated biomedical information in the current reference collection.

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All references with 18alpha-glycyrrhetinic acid

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Authors Title Published Journal PubMed Link
Feng Yeh C et al. Water extract of licorice had anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. 2013 J Ethnopharmacol pmid:23643542
Kao TC et al. Glycyrrhizic acid and 18β-glycyrrhetinic acid recover glucocorticoid resistance via PI3K-induced AP1, CRE and NFAT activation. 2013 Phytomedicine pmid:23218403
Kato R et al. Gap-junction-mediated communication in human periodontal ligament cells. 2013 J. Dent. Res. pmid:23677649
Nishida S and Satoh H Role of gap junction involved with endothelium-derived hyperpolarizing factor for the quercetin-induced vasodilatation in rat mesenteric artery. 2013 Life Sci. pmid:23435092
Kim ME et al. 18β-Glycyrrhetinic acid from licorice root impairs dendritic cells maturation and Th1 immune responses. 2013 Immunopharmacol Immunotoxicol pmid:23438306
Figueroa XF et al. Diffusion of nitric oxide across cell membranes of the vascular wall requires specific connexin-based channels. 2013 Neuropharmacology pmid:23499665
Zong L et al. 18α-glycyrrhetinic acid extracted from Glycyrrhiza radix inhibits proliferation and promotes apoptosis of the hepatic stellate cell line. 2013 J Dig Dis pmid:23362936
Lallemand B et al. Synthesis and plasma pharmacokinetics in CD-1 mice of a 18β-glycyrrhetinic acid derivative displaying anti-cancer activity. 2013 J. Pharm. Pharmacol. pmid:23356849
Hardy ME et al. 18β-glycyrrhetinic acid inhibits rotavirus replication in culture. 2012 Virol. J. pmid:22616823
Tabuchi M et al. The blood-brain barrier permeability of 18β-glycyrrhetinic acid, a major metabolite of glycyrrhizin in Glycyrrhiza root, a constituent of the traditional Japanese medicine yokukansan. 2012 Cell. Mol. Neurobiol. pmid:22488528
Zhao K et al. Inhibition of gap junction channel attenuates the migration of breast cancer cells. 2012 Mol. Biol. Rep. pmid:21674188
Zhou X et al. Antimycobacterial and synergistic effects of 18β-glycyrrhetinic acid or glycyrrhetinic acid-30-piperazine in combination with isoniazid, rifampicin or streptomycin against Mycobacterium bovis. 2012 Phytother Res pmid:21656601
Puchner A et al. Effects of 18β-Glycyrrhetinic acid in hTNFtg mice - a model of rheumatoid arthritis. 2012 Wien. Klin. Wochenschr. pmid:22210441
Zong L et al. 18α-glycyrrhetinic acid down-regulates expression of type I and III collagen via TGF-Β1/Smad signaling pathway in human and rat hepatic stellate cells. 2012 Int J Med Sci pmid:22811611
Moon MH et al. 18β-Glycyrrhetinic acid inhibits adipogenic differentiation and stimulates lipolysis. 2012 Biochem. Biophys. Res. Commun. pmid:22465130
Hong X et al. Gap junctions propagate opposite effects in normal and tumor testicular cells in response to cisplatin. 2012 Cancer Lett. pmid:22115964
Cirillo N et al. Characterization of a novel oral glucocorticoid system and its possible role in disease. 2012 J. Dent. Res. pmid:22067259
Hendricks JM et al. 18β-glycyrrhetinic acid delivered orally induces isolated lymphoid follicle maturation at the intestinal mucosa and attenuates rotavirus shedding. 2012 PLoS ONE pmid:23152913
Sharma G et al. 18β-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells. 2012 J. Cell. Physiol. pmid:21732363
Alderman SL and Vijayan MM 11β-Hydroxysteroid dehydrogenase type 2 in zebrafish brain: a functional role in hypothalamus-pituitary-interrenal axis regulation. 2012 J. Endocrinol. pmid:23042946