| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ciovacco WA et al. | The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. | 2009 | Bone | pmid:18848655 |
| Ye ZC et al. | Pharmacological "cross-inhibition" of connexin hemichannels and swelling activated anion channels. | 2009 | Glia | pmid:18837047 |
| Kalaiarasi P et al. | Hypolipidemic activity of 18beta-glycyrrhetinic acid on streptozotocin-induced diabetic rats. | 2009 | Eur. J. Pharmacol. | pmid:19361497 |
| Li WC et al. | Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of young Xenopus tadpoles. | 2009 | J. Physiol. (Lond.) | pmid:19221124 |
| Sato T et al. | Effect of gap junction blocker beta-glycyrrhetinic acid on taste disk cells in frog. | 2009 | Cell. Mol. Neurobiol. | pmid:19145483 |
| Miguel-Hidalgo J et al. | Infusion of gliotoxins or a gap junction blocker in the prelimbic cortex increases alcohol preference in Wistar rats. | 2009 | J. Psychopharmacol. (Oxford) | pmid:18562436 |
| Kaneda M et al. | Direct formation of proteo-liposomes by in vitro synthesis and cellular cytosolic delivery with connexin-expressing liposomes. | 2009 | Biomaterials | pmid:19423159 |
| Classen-Houben D et al. | Selective inhibition of 11beta-hydroxysteroid dehydrogenase 1 by 18alpha-glycyrrhetinic acid but not 18beta-glycyrrhetinic acid. | 2009 | J. Steroid Biochem. Mol. Biol. | pmid:19429429 |
| Iqbal Choudhary M et al. | Microbial transformation of 18beta-glycyrrhetinic acid by Cunninghamella elegans and Fusarium lini, and lipoxygenase inhibitory activity of transformed products. | 2009 | Nat. Prod. Res. | pmid:19384727 |
| Kalaiarasi P and Pugalendi KV | Antihyperglycemic effect of 18 beta-glycyrrhetinic acid, aglycone of glycyrrhizin, on streptozotocin-diabetic rats. | 2009 | Eur. J. Pharmacol. | pmid:19374864 |
| Kim DE et al. | Glycyrrhizin prevents 7-ketocholesterol toxicity against differentiated PC12 cells by suppressing mitochondrial membrane permeability change. | 2009 | Neurochem. Res. | pmid:19224363 |
| Dey A et al. | Role of connexin 43 in the maintenance of spontaneous activity in the guinea pig prostate gland. | 2010 | Br. J. Pharmacol. | pmid:20735413 |
| Song D et al. | Connexin 43 hemichannel regulates H9c2 cell proliferation by modulating intracellular ATP and [Ca2+]. | 2010 | Acta Biochim. Biophys. Sin. (Shanghai) | pmid:20705586 |
| Sasaki H et al. | 18β-glycyrrhetinic acid inhibits periodontitis via glucocorticoid-independent nuclear factor-κB inactivation in interleukin-10-deficient mice. | 2010 | J. Periodont. Res. | pmid:20682015 |
| Li WC et al. | Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors. | 2010 | J. Neurosci. | pmid:21148000 |
| Geddawy A et al. | Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery. | 2010 | J. Pharmacol. Sci. | pmid:20838025 |
| Kao TC et al. | Glycyrrhizic acid and 18beta-glycyrrhetinic acid inhibit inflammation via PI3K/Akt/GSK3beta signaling and glucocorticoid receptor activation. | 2010 | J. Agric. Food Chem. | pmid:20681651 |
| Verwey LJ and Edwards TM | Gap junctions and memory: an investigation using a single trial discrimination avoidance task for the neonate chick. | 2010 | Neurobiol Learn Mem | pmid:19796702 |
| Xiao Y et al. | 18Beta-glycyrrhetinic acid ameliorates acute Propionibacterium acnes-induced liver injury through inhibition of macrophage inflammatory protein-1alpha. | 2010 | J. Biol. Chem. | pmid:19897483 |
| Plotnikov EY et al. | Cytoplasm and organelle transfer between mesenchymal multipotent stromal cells and renal tubular cells in co-culture. | 2010 | Exp. Cell Res. | pmid:20599955 |
| Lee CS et al. | 18β-Glycyrrhetinic acid potentiates apoptotic effect of trichostatin A on human epithelial ovarian carcinoma cell lines. | 2010 | Eur. J. Pharmacol. | pmid:20868669 |
| Kapeta S et al. | Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts. | 2010 | J. Biol. Chem. | pmid:20068043 |
| Li XD et al. | Panax notoginseng saponins potentiate osteogenesis of bone marrow stromal cells by modulating gap junction intercellular communication activities. | 2010 | Cell. Physiol. Biochem. | pmid:21220939 |
| Kawakami Z et al. | Glycyrrhizin and its metabolite 18 beta-glycyrrhetinic acid in glycyrrhiza, a constituent herb of yokukansan, ameliorate thiamine deficiency-induced dysfunction of glutamate transport in cultured rat cortical astrocytes. | 2010 | Eur. J. Pharmacol. | pmid:19818347 |
| Lin KW et al. | 18β-Glycyrrhetinic acid derivatives induced mitochondrial-mediated apoptosis through reactive oxygen species-mediated p53 activation in NTUB1 cells. | 2011 | Bioorg. Med. Chem. | pmid:21696969 |
| Shetty AV et al. | 18α-glycyrrhetinic acid targets prostate cancer cells by down-regulating inflammation-related genes. | 2011 | Int. J. Oncol. | pmid:21637916 |
| Cavone L et al. | 18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis. | 2011 | Ocul. Immunol. Inflamm. | pmid:21426233 |
| Sun W et al. | Design, synthesis, and sustained-release property of 1,3-cyclic propanyl phosphate ester of 18β-glycyrrhetinic acid. | 2011 | Chem Biol Drug Des | pmid:21244638 |
| Piao H et al. | Effects of connexin-mimetic peptides on perfusion pressure in response to phenylephrine in isolated, perfused rat kidneys. | 2011 | Clin. Exp. Nephrol. | pmid:21153751 |
| Kim SJ et al. | Therapeutic effects of connexin inhibitors on detrusor overactivity induced by bladder outlet obstruction in rats. | 2011 | Urology | pmid:21820587 |
| Wang CY et al. | Glycyrrhizic acid and 18β-glycyrrhetinic acid modulate lipopolysaccharide-induced inflammatory response by suppression of NF-κB through PI3K p110δ and p110γ inhibitions. | 2011 | J. Agric. Food Chem. | pmid:21644799 |
| Ma KT et al. | [18β-glycyrrhetinic acid inhibits outward current of vascular smooth muscle cells of arterioles]. | 2011 | Sheng Li Xue Bao | pmid:22193450 |
| Ukil A et al. | Curative effect of 18β-glycyrrhetinic acid in experimental visceral leishmaniasis depends on phosphatase-dependent modulation of cellular MAP kinases. | 2011 | PLoS ONE | pmid:22194991 |
| Veratti E et al. | 18beta-glycyrrhetinic acid and glabridin prevent oxidative DNA fragmentation in UVB-irradiated human keratinocyte cultures. | 2011 | Anticancer Res. | pmid:21737643 |
| Yu J et al. | Disruption of gap junctions reduces biomarkers of decidualization and angiogenesis and increases inflammatory mediators in human endometrial stromal cell cultures. | 2011 | Mol. Cell. Endocrinol. | pmid:21767601 |
| Autsavapromporn N et al. | Intercellular communication amplifies stressful effects in high-charge, high-energy (HZE) particle-irradiated human cells. | 2011 | J. Radiat. Res. | pmid:21905305 |
| Lee J et al. | Gap junctions contribute to astrocytic resistance against zinc toxicity. | 2011 | Brain Res. Bull. | pmid:21884763 |
| Hardy ME et al. | 18β-glycyrrhetinic acid inhibits rotavirus replication in culture. | 2012 | Virol. J. | pmid:22616823 |
| Zhao K et al. | Inhibition of gap junction channel attenuates the migration of breast cancer cells. | 2012 | Mol. Biol. Rep. | pmid:21674188 |
| Zhou X et al. | Antimycobacterial and synergistic effects of 18β-glycyrrhetinic acid or glycyrrhetinic acid-30-piperazine in combination with isoniazid, rifampicin or streptomycin against Mycobacterium bovis. | 2012 | Phytother Res | pmid:21656601 |
| Niger C et al. | ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:22277757 |
| Suh HN et al. | Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA-mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex. | 2012 | Stem Cells Dev. | pmid:22150760 |
| Boengler K et al. | Mitochondrial connexin 43 impacts on respiratory complex I activity and mitochondrial oxygen consumption. | 2012 | J. Cell. Mol. Med. | pmid:22212640 |
| Zong L et al. | 18α-glycyrrhetinic acid down-regulates expression of type I and III collagen via TGF-Β1/Smad signaling pathway in human and rat hepatic stellate cells. | 2012 | Int J Med Sci | pmid:22811611 |
| Fujiwara H et al. | Endothelium-derived relaxing factor-mediated vasodilation in mouse mesenteric vascular beds. | 2012 | J. Pharmacol. Sci. | pmid:22450195 |
| Shahidullah M et al. | TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. | 2012 | Am. J. Physiol., Cell Physiol. | pmid:22492652 |
| Yang JC et al. | 18β-glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway. | 2012 | Mol. Cell. Biochem. | pmid:22865487 |
| Liu Y et al. | Synthesis and biological evaluation of novel spin labeled 18β-glycyrrhetinic acid derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23122524 |
| Alderman SL and Vijayan MM | 11β-Hydroxysteroid dehydrogenase type 2 in zebrafish brain: a functional role in hypothalamus-pituitary-interrenal axis regulation. | 2012 | J. Endocrinol. | pmid:23042946 |
| Du YM et al. | 18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels. | 2012 | Acta Pharmacol. Sin. | pmid:22609834 |
18alpha-glycyrrhetinic acid
18alpha-glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. 18alpha-glycyrrhetinic acid is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as inhibitors, salivary gland development and branching morphogenesis.
Cross Reference
Introduction
To understand associated biological information of 18alpha-glycyrrhetinic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 18alpha-glycyrrhetinic acid?
18alpha-glycyrrhetinic acid is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 18alpha-glycyrrhetinic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 18alpha-glycyrrhetinic acid?
There are no associated biomedical information in the current reference collection.
What functions are associated with 18alpha-glycyrrhetinic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 18alpha-glycyrrhetinic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with 18alpha-glycyrrhetinic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with 18alpha-glycyrrhetinic acid?
There are no associated biomedical information in the current reference collection.